Navigation Links
Study finds shifting disease burden following universal Hib vaccination
Date:11/10/2011

[EMBARGOED FOR NOV. 11, 2011] Vaccination against Haemophilus influenzae type b, or Hib, once the most common cause of bacterial meningitis in children, has dramatically reduced the incidence of Hib disease in young children over the past 20 years, according to a study published in Clinical Infectious Diseases and available online (http://www.oxfordjournals.com/our_journals/cid/prpaper1.pdf). However, other strains of the bacteria continue to cause substantial disease among the nation's youngest and oldest age groups.

"The Hib vaccine was successful in reducing disease among children 5 years and younger, and now the epidemiology has changed," said lead author Jessica MacNeil, MPH, of the Centers for Disease Control and Prevention, who, with colleagues, analyzed data for the current epidemiology and past trends in the invasive disease over the past two decades following the introduction of the Hib vaccine in the mid-1980s. Most H. influenzae disease in the United States is now caused by other, non-type b strains of the bacteria.

The study authors warn that the highest rates of disease from non-b type strains are in the oldest and youngest age groups, those 65 and older and infants less than a year old. Among children younger than 5 years old, young infants are the most likely to be diagnosed with the disease. Many of these cases occur during the first month of life, and among those, premature and low-birthweight babies are the most vulnerable.

The number of adults 65 and older who become ill due to H. influenzae is also high compared to the rest of the population, according to the study authors. Among those in this group who become sick, nearly 25 percent of the cases are fatal. Risk factors for this age group are harder to interpret, the authors note, as clinical outcomes may be due to underlying medical conditions.

American Indian and Alaska Native children continue to have a disproportionately large burden of both Hib and non-b type disease compared to others, the study found, but the reasons behind this are not fully understood. "Why these groups continue to be at a higher risk than other populations should be the focus of future studies," MacNeil said. Understanding risk factors for H. influenzae disease in this population, such as household crowding, poverty, and poor air quality, could potentially help prevent transmission.

The study authors found that no substantial serotype replacement has been observed among young children in the U.S., which suggests the current Hib vaccine has been effective in preventing H. influenzae illness in this age group. However, the authors note, the burden of disease seen in older adults is an opportunity that could be addressed in the future with an H. influenzae vaccine for adults.


'/>"/>

Contact: John Heys
jheys@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... ... March 22, 2017 , ... An intensive search of the ... HIV, reports Leslie Norins, MD, PhD. He says investigating this possibility, is ... Zika virus and in new infections with HIV. , His findings appear ...
(Date:3/22/2017)... ... March 22, 2017 , ... Last year, 43 million gallons of surplus ... Agriculture report. While excess dairy can be caused by several factors, one pharmaceutical ... the inability to properly digest lactose, a sugar found in milk and milk products. ...
(Date:3/22/2017)... ... ... The Vanderbeck Agency, a Long Island firm providing insurance, financial planning, and ... combined charity effort with the Great Neck Breast Cancer Coalition to provide for patients ... Breast Cancer Coalition has worked to support breast cancer patients in the Long Island ...
(Date:3/22/2017)... ... March 22, 2017 , ... The Zabbia Insurance Agency, ... families and business owners in the greater Nassau County area, is embarking on ... , Every 3 minutes, someone in America is diagnosed with blood cancer. Every ...
(Date:3/22/2017)... D.C. (PRWEB) , ... March 22, 2017 , ... ... budget debt ceiling and prevent a default on the federal debt — including the ... ceiling is a growing concern, ” said TSCL in a letter to House and ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... , March 22, 2017 A new ... Disinfector™ is the proven ultraviolet-C (UV-C) disinfection solution ... infections (HAIs). Published in the ... Infection Control , the peer-reviewed study of UV-C ... of Vancouver General Hospital and Rochester General Hospital. ...
(Date:3/22/2017)... IRVINE, Calif. , March 22, 2017 /PRNewswire/ ... Free Injection System has received an Innovative Technology ... member-driven health care company in the country. The ... J-Tip by hospital representatives with expertise in this ... councils.  Vizient reserves Innovative Technology contracts for technologies ...
(Date:3/22/2017)... 2017 FinancialBuzz.com News Commentary ... industry is strongly contributing to job creation. A recent ... reporting for the cannabis industry, projects that by 2020, ... quarter million jobs for American workers. The legal cannabis ... and is projected to grow at a compound annual ...
Breaking Medicine Technology: