Navigation Links
Study finds reformulated ER Oxycodone abuse rates are significantly lower than original ER Oxycodone
Date:11/14/2012

  • Aims of this study were to assess 1) whether the rates of abuse of extended-release (ER) oxycodone (OxyContin) decline following introduction of reformulated ER oxycodone (ORF), and 2) whether ORF is less likely to be abused through non-oral routes of administration that require tampering
  • Researchers obtained data from 140,496 individuals assessed for substance abuse treatment at 357 treatment centers
  • Findings were consistent with the goals for a tamper resistant formulation, however further research is needed to determine the persistence and generalizability of these initial findings

This is the first epidemiological study to examine the public health impact of a tamper resistant extended-release oxycodone (ORF). ER oxycodone was reformulated with physicochemical barriers to crushing and dissolving intended to reduce abuse through non-oral routes of administration. Manufacturer shipments of original ER oxycodone stopped on August 5, 2010, and ORF shipments started August 9, 2010. During the first 20 months following ORF introduction, it was abused significantly less than the original ER oxycodone when measured by 8 outcome measures, particularly through non-oral routes of administration that require tampering (such as injection, snorting, smoking).

More information on this study can be found in the article, "Abuse rates and routes of administration of reformulated extended-release oxycodone: initial findings from a sentinel surveillance sample of individuals assessed for substance abuse treatment" published in the November 2012 issue of the Journal of Pain.

A sentinel surveillance sample of 140,496 individuals assessed for substance abuse treatment at 357 treatment assessment centers across the country between June 1, 2009 and March 31, 2012 was examined for abuse through oral and non-oral specific routes of administration for ER oxycodone before and after ORF was introduced. Significant reducti
'/>"/>

Contact: Elsbeth McSorley
emcsorley@inflexxion.com
617-614-0369
Inflexxion, Inc.
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Month of Birth Might Help Determine MS Risk, Study Suggests
2. Study Reveals Gender Gap in Spotting Depression
3. Patients More Likely to Survive In-Hospital Cardiac Arrest Today: Study
4. Bright Light at Night Could Up Depression Risk, Mouse Study Suggests
5. Kids Generosity May Depend on Whos Watching: Study
6. Schizophrenia Patients Who Take Antipsychotics Live Longer, Study Says
7. Worlds largest respiratory genetics study launches on World COPD Day
8. Synthetic Skin Heals Itself With a Touch, Study Shows
9. Migraine Sufferers Show More Brain Changes Than Others: Study
10. Kids Headaches Rarely Due to Vision Problems, Study Finds
11. Study demonstrates that earlier end of life care discussions are linked to less aggressive care in final days of life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... 20, 2014 Xarelto bleeding lawsuits ... uncontrollable bleeding and other serious side effects will ... of Louisiana for coordinated pretrial proceedings, Wright & Schulte ... (JPML) issued an order Friday to transfer 21 Xarelto ... 22 federal courts to the Louisiana district court for ...
(Date:12/20/2014)... Today, Balfleet.com, one of the most outstanding ... 50%-70% off on its Mother of the Bride ... of the bride dresses from Balfleet.com feature gorgeous looks ... and takes pride in providing high quality dresses to ... great discounts on our mother of the bride dresses, ...
(Date:12/19/2014)... December 20, 2014 Sweetdressy.com , ... has introduced its newest selection of cheap prom dresses ... very popular in the world and clients can buy ... Meanwhile, these prom dresses feature cool cuts and delicate ... now, targeting the middle-end market. Discount shipping costs are ...
(Date:12/19/2014)... Anaheim, CA (PRWEB) December 19, 2014 ... not-for-profit corporation dedicated to developing educational events, tools ... and Rouxbe Cooking School , the world’s ... develop the prescription every human being needs: Culinary ... and plant-based cooking course, Culinary Rx, scheduled for ...
(Date:12/19/2014)... Eufaula, Oklahoma, located just 9 miles ... state’s largest lake with more than 600 miles of ... a little more than 3,000 residents, hosted its annual ... 6th of December. , Featuring Santa, Christmas lights and ... on Main Street. Narconon Arrowhead’s parade float participated ...
Breaking Medicine News(10 mins):Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 3Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 4Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3
... could produce treatments to reduce cravings, expand calorie burn ... that breaks down and suppresses an appetite stimulant produced ... with The Scripps Research Institute say the antibody catalyst, ... curbed their eating even after the rodents went 24 ...
... Day Bond Referendum to,Support Water, Sewage Systems, ... pointed to a report issued today that measures ... sewer infrastructure and,warns of an impending crisis unless ... systems., The report, compiled by the Sustainable ...
... Physical therapy is a cost-effective form of ... Oct. 31 Patients with,diabetes who participate ... resistance exercise demonstrate improvements in glucose control,physical ... a study,published in the November 2008 issue ...
... Nutrition 21, Inc.,(Nasdaq: NXXI ), a developer and ... levels, improve cardiovascular health,enhance memory and address chronic joint ... opening of the market -- on Thursday,November 13, 2008 ... 30, 2008. The Company has scheduled a conference call ...
... people thought certain illnesses were more dangerous if publicized ... greatly influences how people perceive the threat of infectious ... receive extensive coverage are likely to be regarded as ... the case. , "The media tend to focus on ...
... Blue Cross Blue Shield of Michigan has,closed its Detroit-based ... morning., The closings affect Blue Cross buildings on ... Service Center,buildings. The company,s office building on Jefferson Avenue ... in the impacted facilities are,being sent home for the ...
Cached Medicine News:Health News:Scientists Develop New Strategy to Fight Obesity 2Health News:Governor's Task Force Cites PA's $36.5 Billion Water Infrastructure Need; Report Underscores Call for Additional Investments 2Health News:Governor's Task Force Cites PA's $36.5 Billion Water Infrastructure Need; Report Underscores Call for Additional Investments 3Health News:New Research Shows That Combining Aerobic Exercise With High-Force Eccentric Resistance Training Improves Glucose Control in Diabetes Patients 2Health News:New Research Shows That Combining Aerobic Exercise With High-Force Eccentric Resistance Training Improves Glucose Control in Diabetes Patients 3Health News:Nutrition 21 to Report Preliminary First Quarter Fiscal Year 2009 Financial Results on Thursday, November 13, 2008 2Health News:Media Affects Public Perception of Infectious Diseases 2
(Date:12/19/2014)... , Dec. 18, 2014  Decision Resources Group ... the United States will increase to a ... be primarily driven by expansion in the large direct ... devices will be increasingly adopted due to the advantages ... Other key findings from Decision Resources Group,s coverage ...
(Date:12/19/2014)... , Dec. 18, 2014 Since last month,s ... site now known as the leading online black market ... explosive growth in its offering of drugs and other ... show the takedowns did succeed in lowering the numbers ... review of the markets in August. But some new ...
(Date:12/17/2014)... and SAN DIEGO , Dec. ... PHG ; AEX: PHIA) and Volcano Corporation (NASDAQ: ... measurement solutions for cardiovascular applications, today announced that they have ... Philips will commence a tender offer to acquire all of ... per share, or a total equity purchase price of USD ...
Breaking Medicine Technology:U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 2U.S. Laparoscopic Device Market Will Reach Over $4.3 Billion by 2023 3Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8
... throughout cities nationally, LOS ANGELES and ... a wholly owned subsidiary of SpineMark Corporation, ... to create the,nation,s first multidisciplinary, multisite Spine ... spine experts under one organization.,The SpineMark SROs ...
... present interim results of the Cethrin(R) Phase ... HOPKINTON, Mass., April 9, 2008 Alseres,Pharmaceuticals, Inc. (Nasdaq: ... Dr.,Mark Hurtt, Chief Medical Officer, will discuss the CETHRIN ... Spinal Cord Injury Research,during a congressional briefing on Capitol ...
Cached Medicine Technology:SpineMark Partners With Regional Spine Leaders to Launch Its First Multisite Spine Research Organizations in Los Angeles, Denver 2SpineMark Partners With Regional Spine Leaders to Launch Its First Multisite Spine Research Organizations in Los Angeles, Denver 3Alseres Pharmaceuticals, Inc. to Address a Congressional Briefing on Paralysis Research and the Spinal Cord Injury Community at 'Working 2 Walk' in Washington, DC, April 13-15, 2008 2Alseres Pharmaceuticals, Inc. to Address a Congressional Briefing on Paralysis Research and the Spinal Cord Injury Community at 'Working 2 Walk' in Washington, DC, April 13-15, 2008 3Alseres Pharmaceuticals, Inc. to Address a Congressional Briefing on Paralysis Research and the Spinal Cord Injury Community at 'Working 2 Walk' in Washington, DC, April 13-15, 2008 4
... Guglielmi Detachable Coil is intended for: embolization ... of,their morphology, their location, or the patient's ... the treating,neurosurgical team to be a) very ... techniques, or b) inoperable.,The GDC is also ...
Designed to have a shock-absorbing force, providing less bounce or wasted force....
Slightly curved Periosteal elevator....
Set of 5 large bone curettes. One each of the following: angled small, straight small, angled medium, straight medium, and angled large....
Medicine Products: