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Study finds preterm birth clinic attendance leads to major reduction in infant disability
Date:2/11/2011

managed by their primary obstetrician. The primary outcome was recurrent PTB. Data were analyzed by chi-square and Student's t-test.

Two hundred and thirty-two patients (70 PTB Prevention Clinic and 162 Usual-Care patients) met inclusion criteria. Groups had similar previous pregnancy characteristics. PTB Prevention Clinic patients had increased utilization of resources (including more cervical length ultrasounds and higher rates of use of prophylactic 17OHPC) and delivered at later gestational ages. Rates of NICU admission were similar between groups (44.3% vs. 40.7%, p=0.62). However, rates of major neonatal morbidity (diagnosis of NEC, BPD, IVH, sepsis, or death) were lower among PTB Prevention Clinic neonates (5.3% vs. 15.4%, p=0.025).

The study showed that among this high-risk population, referral to a consultative PTB Prevention Clinic (with standardized counseling, management recommendations, and close surveillance) resulted in a reduction in the rate of recurrent PTB prior to 37 weeks, lead to an average of a one week longer pregnancy, and reduced the rates of major neonatal morbidity.

"The study showed that participants in the preterm birth prevention clinic had a 28 percent reduction in the risk of recurrent spontaneous preterm birth, as well as reductions in infant complications and short term disabilities," said Tracy Manuck, M.D., one of the study's authors. "These are significant improvements and should lead more medical facilities to think about creating similar programs."


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Contact: Vicki Bendure
vicki@bendurepr.com
202-374-9259
Society for Maternal-Fetal Medicine
Source:Eurekalert

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