Navigation Links
Study finds potential markers for severity of childhood arthritis
Date:7/12/2013

Children who suffer from arthritis could one day receive more targeted treatment thanks to potential markers for the severity of the disorder discovered by researchers at the University of Adelaide and Women's and Children's Hospital.

The early results of a world-first study looking at 115 children with juvenile arthritis have shown that changes in the levels of particular molecules known as prostanoids - which are formed from essential fatty acids - in the blood of these patients may predict the course of arthritis more accurately, and help provide more individualized treatment.

"Arthritis in children is almost as common as juvenile diabetes, with up to one in 500 children affected. Despite having many available treatments, not all children with arthritis will respond to standard therapies," says the leader of this research, Dr Christina Boros, Senior Lecturer in the University of Adelaide's School of Paediatrics and Reproductive Health, researcher in the Robinson Institute, and Head of Rheumatology at the Women's and Children's Hospital.

"For many children arthritis can be a physically debilitating and emotionally challenging condition. Some are unable to perform simple tasks because the swelling of their joints can affect their motor skills. Many children with arthritis also suffer from the psychological consequences of having a chronic disease, which can continue with them into adult life.

"Juvenile idiopathic arthritis can present at any age, with some children diagnosed as early as 6-9 months. The longer children go without treatment, the more likely they are to have permanent joint damage," she says.

"So far, we've been able to determine relationships between the blood levels of molecules called prostanoids and disease activity in childhood arthritis. These appear to be more accurate than traditional blood markers of inflammation.

"This is promising research. We are now expanding our study to look at a larger group of children with arthritis, and how prostanoids may predict arthritis disease activity over time as well as how the use of medications affects prostanoid levels."

Dr Boros says that having confirmed biomarkers could not only change how we treat childhood arthritis, but also reduce the physical, emotional and financial burden of the disease.

"There are many medications available for juvenile arthritis but unfortunately there is still no cure. Anything that can improve treatment and prevent joint damage is welcome."


'/>"/>

Contact: Dr. Christina Boros
christina.boros@adelaide.edu.au
61-881-617-000
University of Adelaide
Source:Eurekalert

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2016)... ... May 01, 2016 , ... Women’s Excellence has ... mothers a better understanding of what to expect after they deliver. The guide ... postpartum, · The blues and depression, · Breastfeeding beyond postpartum · Baby basics ...
(Date:5/1/2016)... (PRWEB) , ... May 01, 2016 , ... Good Circle ... in need of chiropractic help. The agency offers a verity of health, life and ... need. According to Chris Nelson at the firm, “Many insurance plans don’t cover chiropractic ...
(Date:4/30/2016)... ... April 30, 2016 , ... Powerful ... with Hypnotherapist, Mary O'Maley. What is hypnosis and hypnotherapy and why after ... weight control), pain relief (chronic and acute), birthing processes and medical procedures, depression, ...
(Date:4/30/2016)... ... April 30, 2016 , ... Dr. Trevor Gardner, ... EMED, today signed a multifaceted agreement which will allow for the research and ... Department of Natural and Applied Sciences, Allied Health and Nursing will work together ...
(Date:4/30/2016)... ... 30, 2016 , ... Orlando-based Maximized Living has selected Dr. Nick Wilson of ... Under the care of Maximized Living doctors at the London Olympics in 2012, ... Living is sending the largest contingent of elite chiropractors to Rio to support and ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... April 28, 2016   Click here for ... Inc. (NYSE: DPLO), the nation,s largest independent specialty ... definitive agreement to acquire Valley Campus Pharmacy, Inc., ... a leading specialty pharmacy that provides individualized patient ... . In 2015, TNH generated approximately $400 ...
(Date:4/28/2016)... Research and Markets has announced the addition ... report to their offering.      (Logo: ... plastic surgery products market is expected to grow at ... ,The growing adoption of laser in aesthetics is another ... Lasers are used to treat a broad range of ...
(Date:4/28/2016)... , April 28, 2016 ... George Phillips und Stephen ...    ArisGlobal®, ein führender Anbieter ... gab heute bekannt, dass neue Führungskräfte zum ... gestoßen sind, die vielfältige Erfahrungen mitbringen.  Dies ...
Breaking Medicine Technology: