Navigation Links
Study finds potential markers for severity of childhood arthritis
Date:7/12/2013

Children who suffer from arthritis could one day receive more targeted treatment thanks to potential markers for the severity of the disorder discovered by researchers at the University of Adelaide and Women's and Children's Hospital.

The early results of a world-first study looking at 115 children with juvenile arthritis have shown that changes in the levels of particular molecules known as prostanoids - which are formed from essential fatty acids - in the blood of these patients may predict the course of arthritis more accurately, and help provide more individualized treatment.

"Arthritis in children is almost as common as juvenile diabetes, with up to one in 500 children affected. Despite having many available treatments, not all children with arthritis will respond to standard therapies," says the leader of this research, Dr Christina Boros, Senior Lecturer in the University of Adelaide's School of Paediatrics and Reproductive Health, researcher in the Robinson Institute, and Head of Rheumatology at the Women's and Children's Hospital.

"For many children arthritis can be a physically debilitating and emotionally challenging condition. Some are unable to perform simple tasks because the swelling of their joints can affect their motor skills. Many children with arthritis also suffer from the psychological consequences of having a chronic disease, which can continue with them into adult life.

"Juvenile idiopathic arthritis can present at any age, with some children diagnosed as early as 6-9 months. The longer children go without treatment, the more likely they are to have permanent joint damage," she says.

"So far, we've been able to determine relationships between the blood levels of molecules called prostanoids and disease activity in childhood arthritis. These appear to be more accurate than traditional blood markers of inflammation.

"This is promising research. We are now expanding our study to look at a larger group of children with arthritis, and how prostanoids may predict arthritis disease activity over time as well as how the use of medications affects prostanoid levels."

Dr Boros says that having confirmed biomarkers could not only change how we treat childhood arthritis, but also reduce the physical, emotional and financial burden of the disease.

"There are many medications available for juvenile arthritis but unfortunately there is still no cure. Anything that can improve treatment and prevent joint damage is welcome."


'/>"/>

Contact: Dr. Christina Boros
christina.boros@adelaide.edu.au
61-881-617-000
University of Adelaide
Source:Eurekalert

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The International Association ... standards of excellence for the field of eating disorders, announces the opening of ... 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. , ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest ... its plans to open a flagship location in Covington, LA at 401 N. U.S. ... Go store next to Office Depot in the Holiday Square shopping center. Its location ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
(Date:10/2/2017)... COPENHAGEN, Denmark , Oct. 2, 2017 The ... tool in the struggle to reverse the tide of prescription ... plan for regulating their medicine intake and stepping down their ... is set to launch in December 2017; the first 100,000 ... access. Learn more at http://www.rebound-solution.com/ ...
(Date:9/25/2017)... 25, 2017   Montrium , an industry ... today—from the IQPC Trial Master Files & Inspection ... that EastHORN Clinical Services has selected eTMF ... TMF management. EastHORN, a leading European contract research ... increase transparency to enable greater collaboration with sponsors, ...
Breaking Medicine Technology: