Navigation Links
Study finds pigs susceptible to virulent ebolavirus can transmit the virus to other animals
Date:5/12/2011

[EMBARGOED FOR MAY 13, 2011] Canadian investigators have shown that a species of ebolavirus from Zaire that is highly virulent in humans can replicate in pigs, cause disease, and be transmitted to animals previously unexposed to the virus. The findings are published in The Journal of Infectious Diseases and are now available online. (Please see below for a link to the embargoed study online.)

In order to prevent human outbreaks of Ebola hemorrhagic fever, it is important to identify animal species that replicate and transmit the virus to other animals and, potentially, people. Zaire ebolavirus, one of several species of the virus, has a fatality rate as high as 90 percent in humans. Antibodies to another species not associated with human disease, known as Reston ebolavirus, have been found in pig farmers in the Philippines, suggesting pigs may be able to transmit virulent ebolavirus to humans as well.

This study, led by Gary P. Kobinger, PhD, of the Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, and Hana Weingartl, PhD, of the National Centre for Foreign Animal Disease at the Canadian Food Inspection Agency, investigated whether Zaire ebolavirus, like Reston ebolavirus, could replicate and cause disease in pigs and be transmitted to other animals. Using domesticated pigs, the researchers first evaluated virus replication, pathogenicity, and shedding.

Following mucosal exposure to Zaire ebolavirus, the pigs replicated the virus in high amounts, mainly in the respiratory tract. Shedding of the virus from nasal mucosa was detected for up to 14 days post-infection, and severe lung disease was observed. The study also showed that the virus was transmitted to all previously unexposed pigs co-habiting with the infected animals.

The study authors suggest that domesticated pigs are susceptible to Zaire ebolavirus through mucosal infection and that the pigs' accompanying severe respiratory disease is associated with shedding of high viral loads into the environment, exposing uninfected pigs to the infection. In contrast to the systemic syndrome affecting multiple organs that often leads to shock and death in primates, they noted, the respiratory syndrome that develops in pigs could be mistaken for other porcine respiratory diseases.

In an accompanying editorial, Daniel G. Bausch, MD, MPH & TM, of the Tulane School of Public Health and Tropical Medicine in New Orleans, noted that the study's findings raise important questions for additional research on ebolavirus. The results described in the study are "cause for consideration, for further scientific study" but are not cause for panic, Dr. Bausch wrote.


'/>"/>

Contact: John Heys
jheys@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... Mediaplanet today announces distribution of ... current obstacles facing infection prevention and offer strategies for the health care community ... , The print component of “Fighting Infection” is distributed within the Friday, ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... According to ... score is invalid because it does not obey the rules Congress has directed the ... equivalent jobs, which the GOP reform would restore. Yet, it estimates a reduction in ...
(Date:3/24/2017)... ... March 24, 2017 , ... Shamanic healer and teacher ... Healing and Spiritual Awakening, proudly presents her Sacred Peru retreat with world ... and spiritual journey during the Summer Solstice will also be her final international ...
(Date:3/24/2017)... ... March 24, 2017 , ... On June 9, 2017, Cassie ... Litigation seminar in Chicago, Illinois. She will present on: , Filing Benefit ... under ERISA involve claims for long-term disability benefits. This session will address ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... enhancements, upgrading their training and leads programs. , In February, 2017, Empower Brokerage ... sales agents, Performance Partners is designed to teach how to maximize their sales ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , March 24, 2017 According to a new ... Analysis and Industry Forecast, 2014-2022," the spine bone stimulators market was valued at ... growing at a CAGR of 3.6% during the forecast period. ... ... Market Research Logo ...
(Date:3/24/2017)... 24, 2017 Research and Markets has announced the ... report to their offering. ... This report analyzes the worldwide markets for Dental Implants in US$ Million. ... , Japan , Europe , ... Rest of World. Annual estimates and forecasts are provided ...
(Date:3/24/2017)... Research and Markets has announced the addition of the "Global ... ... very strong with a total of 97 drug candidates. Pharma giant such ... involved in the development of the IPF therapeutics. The IPF pipeline comprised ... 15 are in Phase II stage, 12 are in Phase I stage, ...
Breaking Medicine Technology: