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Study finds new key to corneal transplant success
Date:7/1/2010

been damaged by injury or illness. It is, in fact, the most common form of tissue transplant. In patients whose corneas are nonvascular at the time of surgery, the chance of success is high: up to 81 percent of transplants remain healthy at five-year follow up.

Ophthalmologists (Eye M.D.s) already use a number of pre-surgery measures to encourage corneal transplant success, such as matching donor and recipient tissues as closely as possible and suppressing the immune response in the person receiving the graft. After transplant the doctor monitors the patient closely for signs of failure and treats early and aggressively if warning signs appear.

Dr. Cursiefen's review found that increasing age and male gender appear to be additional, independent risk factors for graft failure, but not for graft rejection; he says further study is needed to confirm these findings. In June 2009 (Ophthalmology) the Cornea Donor Study reported lower rates of corneal transplant success in patients who had corneal edema (swelling) after surgery for cataract removal and intraocular lens implantation, and in glaucoma patients.


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Contact: Mary Wade
mwade@aao.org
415-447-0221
American Academy of Ophthalmology
Source:Eurekalert

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