Navigation Links
Study finds new key to corneal transplant success
Date:7/1/2010

SAN FRANCISCO, CA Although it is already one of medicine's most successful transplant procedures, doctors continue to seek ways to improve corneal transplants. Now, for the first time, a team of German and British researchers have confirmed that failure and rejection of transplanted corneas are more likely in patients whose eyes exhibit abnormal vessel growth, called corneal neovascularization, prior to surgery. The meta-analysis report appears in July Ophthalmology, the journal of the American Academy of Ophthalmology. The findings also suggest a new treatment approach that could improve transplant success rates.

Claus Cursiefen, MD, and colleagues reviewed 19 studies involving nearly 24,500 corneal transplants (called "grafts"). The cornea is the eye's clear outer surface that provides much of the visual power.

"The presence of corneal neovascularization before surgery makes it about 30 percent more likely that the transplant will fail, and more than doubles the risk of graft rejection," said Dr. Cursiefen. "We also found that the risks of failure and rejection rise with the extent of vascularizationthe more extensive the corneal neovascularization, the higher the risks."

These findings suggest that patients who have corneal neovascularization might benefit from treatment before transplant surgery with growth-inhibiting drugs (antiangiogenics) such as bevacizumab or ranibizumab, or with another type of drug that works at the level of gene transcription to discourage vessel growth; one such drug, GS101, is now in clinical trials. This "preconditioning" approach is worthy of thorough testing and assessment, the researchers say.

"In the future, preconditioning a vascularized cornea before transplantation may be a useful strategy to promote survival of the graft," Dr. Cursiefen said.

More than 40,000 transplant surgeries are performed annually in the United States to restore vision in people whose corneas have
'/>"/>

Contact: Mary Wade
mwade@aao.org
415-447-0221
American Academy of Ophthalmology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Casual Sex Doesnt Cause Emotional Damage: Study
2. Study Finds Possible Explanation for the Link Between Infertility and Breast/Ovarian Cancer Risks
3. Screening for Spinal Muscular Atrophy Not Cost-Effective: Study
4. New study finds possible source of beta cell destruction that leads to Type 1 diabetes
5. New Study Demonstrates Novel Use of Metabolic Imaging to Locate Sperm in Infertile Men -- Non-Invasive Imaging Procedure May Replace Invasive Techniques such as Testicula
6. Risk of stroke lower for recent Ontario immigrants: study
7. Definitive study confirms chemo benefit in postmenopausal breast cancer
8. Experimental stem cell treatment arrests acute lung injury in mice, study shows
9. Violence is part of the job say nurses as study shows only 1 in 6 incidents are reported
10. Controversial Autism Study Retracted by Medical Journal
11. Study Reveals Impact Of Health Insurance On Hispanics' Attitudes Towards Healthcare Providers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... 18, 2014 Medicationdiscountcard.com's ... adding to the company's reputation for helping consumers ... blog has to offer at http://blog.medicationdiscountcard.com/ . ... information concerning the Affordable Care Act and the ... inform the public about a variety of prescription ...
(Date:11/18/2014)... screening for heart disease isn,t effective for people with ... risk for a heart attack, according to a new ... prevent heart attacks or help patients avoid being admitted ... occurs when the heart doesn,t receive enough oxygen-carrying blood). ... to manage risks for heart-related complications, the study authors ...
(Date:11/18/2014)... 2014 Financing for Development Corp. ... financing for international development, has announced the first ... six Directors: Mr. John Skibiak of the Reproductive ... Millennium Challenge Corporation, Mr. Pape Gaye of IntraHealth ... Mr. Aron Betru of Financing for Development, and ...
(Date:11/18/2014)... Virginia (PRWEB) November 18, 2014 Sometimes ... frustrating situations with print devices like unforeseen error messages ... they don't have time to find another printer and ... issue. The IT department is likely tied up with ... , That’s where Electronic Systems, Inc. ...
(Date:11/18/2014)... Recently, Wigsbuy has introduced its newest collection of ... greatly discounted prices now, up to 85% off. , Wigsbuy ... products, offering many real and synthetic hair products. In order ... uses high quality materials to make its hair wigs, which ... , “We are offering a full line of human ...
Breaking Medicine News(10 mins):Health News:Medicationdiscountcard.com Building Virtual Library of Resources to Help Consumers Navigate Healthcare Landscape 2Health News:Study Finds No Added Benefit From Routine Heart Scans for Diabetics 2Health News:Study Finds No Added Benefit From Routine Heart Scans for Diabetics 3Health News:Financing for Development Corp. (F4D) Announces Board of Directors 2Health News:Financing for Development Corp. (F4D) Announces Board of Directors 3Health News:Financing for Development Corp. (F4D) Announces Board of Directors 4Health News:Electronic Systems, providing Managed Print Services (MPS) in Virginia & Outer Banks North Carolina 2Health News:It Is The Most Wonderful Time To Buy Full Lace Wigs At Wigsbuy.com 2
... Team suggests screening spares patients lifetime of problems , , ... lifetime of problems with getting a good night,s sleep ... attention-deficit hyperactivity disorder (ADHD). , The study of 281 ... with ADHD, found that regardless of the severity of ...
... Takes Place on the Eve of the 8th Annual National ... for 14 straight years, the teen birth rate in the ... in Washington, DC sponsored by The National Campaign to Prevent ... rate is increasing and will explore ways to try to ...
... the Product Offering of Avalign Technologies, Inc.LAKE ... Partners ("RoundTable"), an operating-oriented private equity firm ... today that its portfolio company, Avalign ... of instruments, implants, and delivery systems to ...
... resulting from high-energy blasts is one possible underlying causeROSEMONT, ... who are wounded in combat as the result of ... likely to develop an abnormality known as heterotopic ossification. ... such as muscle located near a fracture or other ...
... LIFE Urges Americans to Think About Income Protection, Offers Tips ... The results of a new survey show the historic ... investments -- and as a consequence, they are more vulnerable ... become sick or hurt and couldn,t work. According to the ...
... and Afghanistan ... To help ease the transition and readjustment challenges facing Iraq and ... America (IAVA) joined the Ad Council today to launch a new ... Campaign. Launched on Veterans Day 2008, the first series of ads ...
Cached Medicine News:Health News:Treating Sleep Disorders May Ease ADHD Symptoms 2Health News:Forum Explores Solutions to the Rise in the Teen Birth Rate 2Health News:Forum Explores Solutions to the Rise in the Teen Birth Rate 3Health News:RoundTable Healthcare Partners Completes Portfolio Company Add-On Acquisition 2Health News:RoundTable Healthcare Partners Completes Portfolio Company Add-On Acquisition 3Health News:Injured Marines at Risk for Abnormal Bone Growth 2Health News:Injured Marines at Risk for Abnormal Bone Growth 3Health News:Hit Hard by the Economy, Americans Risk Knockout Without Disability Insurance 2Health News:Hit Hard by the Economy, Americans Risk Knockout Without Disability Insurance 3Health News:Hit Hard by the Economy, Americans Risk Knockout Without Disability Insurance 4Health News:Video: IAVA and Ad Council Build on Success of Groundbreaking Veterans Campaign with New Friends and Family Element 2Health News:Video: IAVA and Ad Council Build on Success of Groundbreaking Veterans Campaign with New Friends and Family Element 3Health News:Video: IAVA and Ad Council Build on Success of Groundbreaking Veterans Campaign with New Friends and Family Element 4
(Date:11/18/2014)... MUMBAI , November 18, 2014 ... thorough knowledge of the overall new requirements of application ... China but also provides the guidance ... approval for your products entry into the Chinese medical ... Chinese medical device market is one of segment market ...
(Date:11/18/2014)... , Nov. 18, 2014  Cardica, Inc. ... the Cardica Board has approved management,s recommendation to ... launch of the MicroCutter XCHANGE® 30 surgical stapler ... commercial launch.  As a result, Cardica has temporarily ... withdrawing its latest iteration of the MicroCutter XCHANGE ...
(Date:11/18/2014)... Nov. 18, 2014  Palatin Technologies, Inc. ... targeted, receptor-specific peptide therapeutics for the treatment ... and commercial potential, today announced results for ... Recent Highlights , ... , €7.5M ($9.8M) total upfront payment - ...
Breaking Medicine Technology:Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 2Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 3Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 4Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 5Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 6Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 7Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation in China (2014 Edition) 8Cardica Announces Shift In Focus 2Cardica Announces Shift In Focus 3Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2015 Results; Teleconference and Webcast to be held on November 18, 2014 2Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2015 Results; Teleconference and Webcast to be held on November 18, 2014 3Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2015 Results; Teleconference and Webcast to be held on November 18, 2014 4Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2015 Results; Teleconference and Webcast to be held on November 18, 2014 5Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2015 Results; Teleconference and Webcast to be held on November 18, 2014 6Palatin Technologies, Inc. Reports First Quarter Fiscal Year 2015 Results; Teleconference and Webcast to be held on November 18, 2014 7
... Conference: February 13-16, 2012 ,Exposition: February ... Organizers of the Medical Design and Manufacturing (MD&M) West ... be held at the Anaheim Convention Center, February 13-16, ... event in the United States dedicated to medical design ...
... N.C., Jan. 20, 2012  As the pace of ... has become challenging for the biopharma industry to ... messages. Consumers, key opinion leaders, payers ... and biotech companies reach out to with marketing ...
Cached Medicine Technology:MD&M West 2012 to Feature Twenty Collocated Conferences 2Utilizing Marketing Innovations to Engage with Customer Groups that are Key to the Pharmaceutical Industry 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: