Navigation Links
Study finds multiple neglected tropical diseases effectively treated with drugs
Date:10/25/2007

The neglected tropical diseases are a group of 13 infectious diseases, including elephantiasis, hookworm, African sleeping sickness and trachoma, which affect more than 1 billion people worldwide, most of whom live in extreme poverty. In a study published in the most recent Journal of the American Medical Association, Madhuri Reddy, M.D., M.Sc., a geriatrician at Hebrew SeniorLife in Boston, says that treating two or more of them simultaneously for only pennies per dose can facilitate treatment of these diseases.

At least two of the most prevalent neglected tropical diseases can be potentially treated simultaneously with existing oral drug treatments, writes Dr. Reddy, facilitating effective and efficient treatment. Increasing awareness about neglected tropical diseases, their global impact, and the availability of oral drug treatments is an essential step in controlling these diseases.

While inexpensive oral medications are available to treat these conditions, the drugs are often not accessible to the people affected by them, most of them living without access to health care in remote areas on less than $2 per day. These diseases are perpetuated by unsafe water, poor sanitation, and substandard housing conditions. Infection with neglected tropical diseases can lead to lifelong disabilities, disfigurement and, if left untreated, early death. Together, they contribute to nearly 500,000 deaths per year, a number almost as high as HIV/AIDS, tuberculosis or malaria.

Despite the huge impact of neglected tropical diseases worldwide, says Dr. Reddy, the ability to treat them is largely unknown in the medical community, and there is little public awareness of and response to this problem.

Dr. Reddy and her colleagues reviewed 29 randomized control trials of oral drug treatments for neglected tropical diseases. They found that existing oral medications can be used to treat two or more of the most prevalent neglected tropical diseases simultaneously and that four of the seven most prevalent neglected tropical diseases can be treated with a single oral drug combination. In most cases, these drugs cost less than a nickel per dose.

A number of initiatives are underway to reduce the prevalence of these diseases. The U.S. government has committed $15 million to support neglected tropical disease control, and the Bill & Melinda Gates Foundation donated $46.7 million in grants toward developing methods of eliminating these diseases. Pharmaceutical companies have donated drugs valued at more than $1 billion toward this integrated treatment approach.

Researchers estimate that approximately 500 million people at risk for neglected tropical diseases in African could be treated with four effective drug therapies at an annual cost of less than US $0.40 per person, the researchers write in JAMA.

The neglected tropical diseases reviewed include roundworm and whipworm, which impair growth and cognitive function and affects nearly 2 billion people; hookworm, which causes malnutrition and anemia; snail fever, which affect growth and school performance and cause renal failure; elephantiasis, which disfigures limbs and genitalia; trachoma, the leading cause of preventable blindness in the world; river blindness, which causes eye lesions and dermatitis; black fever, the second leading parasitic killer; Chagas disease, which causes irreversible heart, esophagus and colon damage and affects mostly children; and leprosy, which affects the nerves, skin, limbs and eyes.

Dr. Reddy and her colleagues say that drug-based alone control cannot reduce the prevalence of neglected tropical diseases without fundamental public health measures such as access to clean water, adequate sanitation, and access to health-care services. Hebrew SeniorLife is committed to maximizing the quality of life of seniors through an integrated system of housing, health care, research and teaching programs.


'/>"/>

Contact: Scott Edwards
edwards@hrca.harvard.edu
617-363-8385
Hebrew SeniorLife Institute for Aging Research
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... 25, 2016 , ... Dr. Calvin Johnson has dedicated his ... implemented orthobiologic procedures as a method for treating his patients. The procedure is ... to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use to help ...
(Date:6/24/2016)... , ... June 24, 2016 , ... A recent ... most people are unfamiliar with. The article goes on to state that individuals are ... many of these less common operations such as calf and cheek reduction. The Los ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 26, 2016 Story Highlights: ... models within the health care industry is causing providers ... , Deloitte offers a suite of solutions for ... impacting efficient cost optimization: labor resource analysis, revenue cycle ... facilitate better outcomes and better economics ...
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... 24, 2016 Dehaier Medical Systems Ltd. (NASDAQ: ... develops, markets and sells medical devices and wearable sleep ... a strategic cooperation agreement with Hongyuan Supply Chain Management ... on June 20, 2016, to develop Dehaier,s new Internet ... agreement, Dehaier will leverage Hongyuan Supply Chain,s sales platform ...
Breaking Medicine Technology: