Navigation Links
Study finds link between birth order and asthma symptoms
Date:5/8/2008

May 7, 2008 Among four year-olds attending Head Start programs in New York City, those who had older siblings were more likely to experience respiratory symptoms including an episode of wheezing in the past year than those who were oldest or only children. Children with at least two older siblings were also 50% more likely than other children to have gone to an emergency department or been hospitalized overnight for breathing problems. These findings from the Columbia University Mailman School of Public Health were recently pre-published online in the journal Clinical and Experimental Allergy.

Our findings support the hypothesis that having older siblings increases a childs risk of exposure to infectious agents before age two years, and in turn increases the childs risk for wheezing, said Matthew Perzanowski, PhD, assistant professor of Environmental Health Sciences at the Mailman School of Public Health and the lead author of the paper. Some studies have found that having older siblings increases the risk of wheeze in babies and toddlers. Our findings are novel in that we found that among the four year-olds in this study, the pattern was the same as has been observed in younger children elsewhere.

The children in the study were selected for participation because they attended Head Start programs in neighborhoods with the highest rates of childhood asthma hospitalization in New York City.

One possible explanation for the association is that children with older siblings have more exposure to respiratory infections at an early age than oldest or only children. Respiratory infections are a common cause of wheezing in very young children. This study shows that children with older siblings may be appropriate targets for interventions to reduce the risk of infections that may lead to hospitalization.

Previous findings of the opposite association between asthma and birth order among older children and adults have served as the basis for what is called the hygiene hypothesis, the idea that exposure to infectious agents at a very young age reduces the risk of asthma in the long term. Only by continuing to follow these children can we determine whether and how birth order predicts diagnosed asthma and asthma that persists throughout childhood, noted Inge Goldstein, DrPH, a senior lecturer in the Mailman Schools Department of Epidemiology and senior author of the study.

But even if the patterns of association change as the children grow, we have learned from this study that four year-olds with older siblings are more likely than other four year-olds to experience respiratory symptoms that burden them and their families and impose the costs of care on them and the community, commented Judith Jacobson, DrPH, associate professor of clinical Epidemiology at the Mailman School and principal investigator of the study, which was funded by the National Heart, Lung, and Blood Institute.

In this study, the prevalence of recent wheeze was higher among boys than girls (32% vs 21%) and higher among children with an asthmatic parent than other children (53% vs 22%). Having younger siblings, unlike having older siblings, was not associated with respiratory symptoms. The associations of birth order with respiratory symptoms were statistically significant only among those children who were not atopic (allergic) and among those without an asthmatic parent.


'/>"/>

Contact: Stephanie Berger
sb2247@columbia.edu
212-305-4372
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... , ... According to a new study by NCPA Senior Fellow John R. ... rules Congress has directed the CBO to follow. The CBO itself previously recognized Obamacare ... it estimates a reduction in employer-based coverage due to the GOP reform, which is ...
(Date:3/24/2017)... ... ... The iaedp Foundation, the premier provider of educational programs and training standards for eating ... of disordered eating, announced today that the 2017 Symposium set a new attendance record ... countries converged on the Green Valley Resort in Las Vegas. , “We are ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... Premier Center for Shamanic Healing and Spiritual Awakening, proudly presents her Sacred ... 2017. This sacred and spiritual journey during the Summer Solstice will also ...
(Date:3/24/2017)... ... March 24, 2017 , ... As ... to create a communications platform that positions them as the go-to thought leader ... reinvented their online publication as an always-on, always-fresh news, views and advocacy engine, ...
(Date:3/24/2017)... ... March 24, 2017 , ... On June ... ERISA Benefit Claims Litigation seminar in Chicago, Illinois. She will present on: ... of cases litigated under ERISA involve claims for long-term disability benefits. This ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... 23, 2017  HealthMine surveys with 9,250 insured consumers ... health plan members want help from their plans in ... in their health, 2) help closing gaps in care, ... health and 5) relevant, real-time guidance. Meeting these needs ... costs. A Reason to Stay ...
(Date:3/24/2017)... , March 23, 2017  Provectus Biopharmaceuticals, ... the "Company"), a clinical-stage oncology and dermatology biopharmaceutical ... Definitive Financing Commitment Term Sheet (the "Definitive Financing") ... group of the Company,s stockholders, who are referred ... in a Form 8-K filed with the Securities ...
(Date:3/24/2017)... 24, 2017 The Board of Directors of ... Report 2016 including the complete 2016 Annual Accounts with notes. ... Nordic Nanovector,s website in the section Investor Relations/Reports and presentations/Annual ... ... Kvåle, Chief Financial Officer Cell: +47-91-51-95-76 Email: ir@nordicnanovector.com ...
Breaking Medicine Technology: