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Study finds least aggressive form of breast cancer still poses risk for death years later
Date:9/18/2012

metastases.

Of the four subtypes, luminal A is the most common and is responsible for 42 to 59 percent of all breast cancer cases.

Breast cancer is the second-leading cause of cancer death in women and will be responsible for nearly 40,000 deaths among U.S. women this year, according to the American Cancer Society. The risks for developing breast cancer increase as a woman ages, while other factors include genetics, personal health history, and diet.

"These and earlier findings strongly support molecular subtypes as important independent predictors of breast cancer mortality," said Haque. "It is important for women with breast cancer, even those diagnosed with the least aggressive form of the disease, to be an advocate for their own health and speak to their doctors about treatment options."

Researchers suggest that future breast cancer studies should focus on identifying factors that are associated with longer survival in women with luminal A tumors as well as how the association between breast cancer molecular subtypes and survival varies by race and ethnicity, particularly in minority women who are more likely to have aggressive tumor subtypes.

This study is the latest Kaiser Permanente research effort to understand the effects of breast cancer. In January, Kaiser Permanente Colorado Institute for Health Research contributed to new research that reveals substantial differences by both surgeon and institution in the rates of follow-up surgeries for women who underwent a partial mastectomy for treatment of breast cancer. The differences, which cannot be explained by a patient's medical or treatment history, could affect both cancer recurrence and overall survival rates, according to the study.

And last year, research scientists at the Kaiser Permanente Northern California Division of Research found that breast cancer survivors who experience significant weight gain have an increased risk of death after diagnos
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Contact: Vincent Staupe
vstaupe@golinharris.com
415-318-4386
Kaiser Permanente
Source:Eurekalert

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