Navigation Links
Study finds important risk factors for death/transplantation in children with heart muscle disease
Date:7/25/2011

WHAT: Researchers have identified important risk factors for death and transplantation in children with dilated cardiomyopathy (heart muscle disease), according to results from a study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

Using these risk factors, physicians may be able to better identify children who will or will not benefit from life-saving transplantation surgery; the current criteria for receiving a transplant sometimes miss children who may benefit.

If the findings of the report are successfully used nationwide, the indications for heart transplantation may be broadened giving more children access to this life-prolonging therapy.

"Competing risks for death and cardiac transplantation in children with dilated cardiomyopathy: results from the Pediatric Cardiomyopathy Registry," was published online today in Circulation, the journal of the American Heart Association.

Risk factors identified for either death, transplantation, or both include presence of congestive heart failure, echocardiographic evidence of more severe disease, increased age, dilation of the left ventricle, and height. Short stature increased the risk of death but not transplantation. Researchers also found that the causes of dilated cardiomyopathy strongly affected which risk factors were predictive of death and/or transplantation. This suggests that establishing the cause of disease as soon as possible is critically important.

This population-based study used data from the Pediatric Cardiomyopathy Registry (PCMR). From 1990 to 2007, the PCMR, led by the University of Miami Leonard M. Miller School of Medicine, enrolled 1,731 children (18 years of age or younger) diagnosed with pediatric dilated cardiomyopathy, the most common heart muscle disease. Dilated cardiomyopathy can lead to heart valve problems, arrhythmias (irregular heartbeats), blood clots in the heart, and even heart failure.

For 57 percent of children who suffer from cardiomyopathy, the cause of the disease is unknown. The nationwide registry was established to collect and organize data on the condition, which will help determine the causes of the disease and lead to new and better treatments.


'/>"/>

Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

Related medicine news :

1. Kids With ADHD Less Adept at Crossing the Street: Study
2. Chickenpox Vaccine May Wipe Out Related Deaths: Study
3. New study finds cancer-causing mineral in US road gravel
4. Study examines screening for pancreatic cancer in high-risk populations
5. Blue-Collar Employees With Arthritis Working Past 65: Study
6. Gay, Lesbian, Bisexual Teens Often Homeless: Study
7. Teen Athletes at Greater Risk for Osteoarthritis: Study
8. Study: Doctors differ in how best to care for Americas 12 million cancer survivors
9. Medieval Armor Drained Soldiers Energy, Study Finds
10. Drexel study: Misuse of pain medication is pathway to high-risk behaviors
11. Children Fare OK if Mom Works, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... , ... March 24, 2017 , ... ... for contaminated soil, dredged material, and hazardous and non-hazardous materials announced today the ... Pennsylvania. This acquisition will add four additional processing facilities and a vast ...
(Date:3/24/2017)... ... March 24, 2017 , ... Infectious disease affects billions ... the United States, it’s a threat that is constantly changing and evolving. Mediaplanet's ... and offers strategies for the healthcare community to help decrease the number of ...
(Date:3/24/2017)... ... 24, 2017 , ... According to a new study by NCPA Senior Fellow ... obey the rules Congress has directed the CBO to follow. The CBO itself previously ... restore. Yet, it estimates a reduction in employer-based coverage due to the GOP reform, ...
(Date:3/24/2017)... ... March 24, 2017 , ... Mlynarek Insurance ... to families and business owners across eastern Michigan, is connecting with the Oxford/Orion ... with financial difficulties. , The Oxford/Orion FISH Food Pantry works to ensure homeless, ...
(Date:3/24/2017)... ... 24, 2017 , ... As the standards bearer of advanced ... that positions them as the go-to thought leader in all matters concerning oncology ... an always-on, always-fresh news, views and advocacy engine, called ONS Voice. , The ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , March 24, 2017 New England Pediatric ... of an award including funding and in-kind service towards ... technology.  "Making blood draws less traumatic ... their whole hospital experience better.  We,re looking forward to ... can help improve care for the kids we treat," ...
(Date:3/24/2017)... Research and Markets has announced the ... Strategies" report to their offering. ... Pain Management in the ... their physical pain, emphasizing consumer survey analysis, including trends over ... adults who have selected illnesses/conditions strongly associated with physical pain ...
(Date:3/24/2017)... 24, 2017 ShangPharma, a leading ... cost-effective drug development and discovery services, technology, ... industry, announced today the intent for a ... be consolidating the Contract Research Organizations (CRO) ... ChemPartner. These entities include ChemPartner Shanghai, ChemPartner ...
Breaking Medicine Technology: