Navigation Links
Study finds important risk factors for death/transplantation in children with heart muscle disease
Date:7/25/2011

WHAT: Researchers have identified important risk factors for death and transplantation in children with dilated cardiomyopathy (heart muscle disease), according to results from a study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

Using these risk factors, physicians may be able to better identify children who will or will not benefit from life-saving transplantation surgery; the current criteria for receiving a transplant sometimes miss children who may benefit.

If the findings of the report are successfully used nationwide, the indications for heart transplantation may be broadened giving more children access to this life-prolonging therapy.

"Competing risks for death and cardiac transplantation in children with dilated cardiomyopathy: results from the Pediatric Cardiomyopathy Registry," was published online today in Circulation, the journal of the American Heart Association.

Risk factors identified for either death, transplantation, or both include presence of congestive heart failure, echocardiographic evidence of more severe disease, increased age, dilation of the left ventricle, and height. Short stature increased the risk of death but not transplantation. Researchers also found that the causes of dilated cardiomyopathy strongly affected which risk factors were predictive of death and/or transplantation. This suggests that establishing the cause of disease as soon as possible is critically important.

This population-based study used data from the Pediatric Cardiomyopathy Registry (PCMR). From 1990 to 2007, the PCMR, led by the University of Miami Leonard M. Miller School of Medicine, enrolled 1,731 children (18 years of age or younger) diagnosed with pediatric dilated cardiomyopathy, the most common heart muscle disease. Dilated cardiomyopathy can lead to heart valve problems, arrhythmias (irregular heartbeats), blood clots in the heart, and even heart failure.

For 57 percent of children who suffer from cardiomyopathy, the cause of the disease is unknown. The nationwide registry was established to collect and organize data on the condition, which will help determine the causes of the disease and lead to new and better treatments.


'/>"/>

Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung and Blood Institute
Source:Eurekalert

Related medicine news :

1. Kids With ADHD Less Adept at Crossing the Street: Study
2. Chickenpox Vaccine May Wipe Out Related Deaths: Study
3. New study finds cancer-causing mineral in US road gravel
4. Study examines screening for pancreatic cancer in high-risk populations
5. Blue-Collar Employees With Arthritis Working Past 65: Study
6. Gay, Lesbian, Bisexual Teens Often Homeless: Study
7. Teen Athletes at Greater Risk for Osteoarthritis: Study
8. Study: Doctors differ in how best to care for Americas 12 million cancer survivors
9. Medieval Armor Drained Soldiers Energy, Study Finds
10. Drexel study: Misuse of pain medication is pathway to high-risk behaviors
11. Children Fare OK if Mom Works, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2017)... GA (PRWEB) , ... April 27, 2017 , ... Are ... a tragic spike in water-related accidents and drownings during the summer. While most of ... is that these situations occur every day. Very few people are taking the time ...
(Date:4/26/2017)... ... 2017 , ... Journal of Oral Implantology – Tooth loss is ... dental health, including complications with speech, eating, and overcompensation of mouth due to the ... teeth. As the number of tooth replacements increase, it is imperative to design an ...
(Date:4/26/2017)... ... April 26, 2017 , ... Elisabete ... has been honored by Enterprising Women magazine as one of its 2017 Enterprising ... women business owners. Winners have demonstrated that they have fast-growth businesses, mentor or ...
(Date:4/26/2017)... ... April 26, 2017 , ... RawTrition now brings you BioEnergy which is a ... SUPERFOODS! , RawTrition is taking nutrients to the next level! The ... recognizes its raw form (unlike the synthetically made options that are on the market). ...
(Date:4/26/2017)... ... April 26, 2017 , ... ... is proud to announce that it has received 510(k) clearance from the U.S. ... Home and the MyoCycle Pro. , Both devices are stationary cycling systems that ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... DUBLIN , April 20, 2017 Research ... Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables Market and ... to their offering. ... market for drug delivery technologies will rise from USD 20 Billion ... Global Drug Delivery Technologies - Innovation Driven by Rapidly ...
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ... 99 percent (n=145/146) of chronic hepatitis C virus ... 5 or 6 and compensated cirrhosis (Child-Pugh A) ... (SVR 12 ) with its investigational, pan-genotypic regimen ... rates were seen following 12 weeks of G/P ...
(Date:4/20/2017)... 20, 2017 NeuroVive Pharmaceutical AB (Nasdaq ... positive preclinical results demonstrating anti-fibrotic effects with ... steatohepatitis (NASH), in an additional well-validated experimental ... has previously shown similar anti-fibrotic effects in ... scientists present novel data demonstrating anti-fibrotic effects ...
Breaking Medicine Technology: