Navigation Links
Study finds heart failure is rare among leukemia patients on imatinib
Date:9/6/2007

HOUSTON - Congestive heart failure rarely occurs among leukemia patients who take imatinib, researchers at The University of Texas M. D. Anderson Cancer Center found after an exhaustive review of the detailed medical histories of 1,276 patients who enrolled in clinical trials for the drug.

Researchers found 22 patients, or 1.7 percent, had symptoms that could have been caused by heart failure. Of those, 18 had previous medical conditions that could also cause heart failure, such as type II diabetes, hypertension, irregular heartbeat or coronary artery disease. Six had congestive heart failure before entering treatment. The results were reported in the Aug. 15 edition of the journal Blood.

"Imatinib remains a safe drug, but monitoring patients and knowing their medical histories are always important," says Jorge Cortes, M.D., senior author of the report and professor in M. D. Anderson's Department of Leukemia. "There is no current need for routine cardiac-specific monitoring of all patients taking imatinib. However, those with significant cardiac history need to be closely monitored. Patients who develop symptoms of heart failure should be evaluated carefully and treated with standard therapy."

Of the 22 patients found to have cardiovascular conditions, 11 were able to continue on imatinib for their leukemia after dose adjustments and management of the heart failure symptoms. The standard of care for treatment includes the use of beta blockers and angiotensin converting enzyme inhibitors or angiotensin receptor blockers, notes study co-author Jean-Bernard Durand, M.D., an assistant professor in M. D. Anderson's Department of Cardiology. Both classes of drugs are approved by the FDA for treatment of heart failure and recommended by the Heart Failure Society of America.

The team also found the incidence of congestive heart failure among patients receiving imatinib to be comparable to the expected incidence in the general pop
'/>"/>

Contact: Scott Merville
sdmervil@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Gene study links endometriosis, infertility
2. Study reveals how stress can make you sick
3. Study points out that HIV vaccine may not be accepted easily
4. A new study surpasses Gene Therapy Hurdle
5. Tomato Sauce reduces Cancer Risk- Study
6. A question on study of Adult Stem Cell
7. Study on obesity and heart failure
8. National Lung Study in the process
9. Marijuana gateway theory strengthened by study of twins
10. Old theory of adaptation confirmed by new study
11. Study casts doubt on keyboard ills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... Bill Howe ... companies in San Diego. Bill Howe offers all employees ample opportunity for education ... but most notably through the local Plumbing-Heating-Cooling-Contractors of San Diego (PHCC-SD). The San ...
(Date:6/30/2015)... ... ... Intellitec Solutions has announced they will be hosting two webinars to answer ... and new procedures involved with updating the cloud version of Dynamics CRM, attendance is ... user interface and what it will mean for end users, critical items that need ...
(Date:6/30/2015)... ... June 30, 2015 , ... Americans report feeling more stressed than ever before. ... which puts stressed out people right over the edge. , Almost half of ... deprivation every night. Sleeping pills now lead the list of the most prescribed medications, ...
(Date:6/29/2015)... NY (PRWEB) , ... June 30, 2015 , ... ... honors Melanie Richards as a 2015-2016 inductee into its VIP Woman ... in business. NAPW is the nation’s leading networking organization exclusively for professional women, ...
(Date:6/29/2015)... , ... June 30, 2015 , ... Ticket Down is ... Soldier Field over the 4th of July weekend. Concertgoers can add promo/coupon code ... only recently caught on to their innovative sound, will not want to miss what ...
Breaking Medicine News(10 mins):Health News:Two Local San Diego Plumbers from Bill Howe Plumbing, Inc. Graduate from PHCC Academy 2Health News:Two Local San Diego Plumbers from Bill Howe Plumbing, Inc. Graduate from PHCC Academy 3Health News:Intellitec Solutions to Host Microsoft CRM 2015 Update Webinar 2Health News:Wake UP Happy and Sleep Soundly with Famous Experts with My Wake UP Call® Motivational Alarm Clock® Messages and My Good Night Messages™ - Now Available at Audible! 2Health News:Wake UP Happy and Sleep Soundly with Famous Experts with My Wake UP Call® Motivational Alarm Clock® Messages and My Good Night Messages™ - Now Available at Audible! 3Health News:National Association of Professional Women Inducts Melanie Richards, DMD, of Powdersville Pediatric Dentistry, Into its VIP Woman of the Year Circle 2Health News:Grateful Dead Tickets at Soldier Field in Chicago: Ticket Down Slashes Grateful Dead Tickets Prices in Chicago at Soldier Field 2Health News:Grateful Dead Tickets at Soldier Field in Chicago: Ticket Down Slashes Grateful Dead Tickets Prices in Chicago at Soldier Field 3
... heart expert calls it ,second-line, medication , , FRIDAY, ... the highly promoted cholesterol-lowering drug Vytorin continued Friday ... the medication,s effectiveness, but only after final trial ... this month when preliminary results of the so-called ...
... WellPoint, Inc. (NYSE:,WLP) announced today that senior ... Conference on January 30, 2008. The presentation is,expected ... All interested parties are invited to listen ... http://www.wellpoint.com and selecting the "Investor,Info" link. Following ...
... Ronit Calderon-Margalit, MD, MPH, Marianna Mazar, MD and Zvi ... Jewish and Arab diabetes sufferers who were admitted to ... whether differences existed between the two groups and, if ... health insurance coverage. The researchers found significant differences. As ...
... Jan. 25 Pizza, nachos, dip and wings ... also have one thing in common:,they can all ... counter heartburn medicine based on dollar sales, is ... tasty heartburn-friendly,alternatives., , Listen to this report ...
... Belgium have significantly advanced the discovery of a pancreatic ... beta cells. If the finding made in mice holds ... obvious target for therapeutic regeneration of beta cells in ... of the research journal Cell, a publication of Cell ...
... The North Carolina,Association of Educators (NCAE) will launch a ... at increasing awareness about good eating,habits and physical fitness ... from NCAE," is slated to run in,newspapers across North ... NCAE logo -- star in an ad campaign to,encourage ...
Cached Medicine News:Health News:FDA Will Wait for Trial Results on Vytorin 2Health News:FDA Will Wait for Trial Results on Vytorin 3Health News:WellPoint Announces Appearance at Upcoming Conference 2Health News:Elusive pancreatic progenitor cells found in mice 2Health News:NCAE Encourages Minority Youth and Their Families to 'Go-for' Health and Fitness 2
(Date:6/29/2015)... , June 29, 2015  PDL BioPharma, Inc. ... entered into a credit agreement with CareView Communications, Inc. ... to $40 million of secured debt financing. CareView is ... on patient care monitoring. Under the credit ... million of debt financing in two tranches of $20 ...
(Date:6/29/2015)... Minn. , June 29, 2015 EnteroMedics ... of devices that use neuroblocking technology to treat obesity, ... it has commenced an underwritten public offering of units. ... stock, Series A warrants to purchase common stock and ... purchase of units in the offering would result in ...
(Date:6/29/2015)... , June 29, 2015  Allergan plc ... intends to release second quarter 2015 financial results ... open of the U.S. financial markets. The Company will ... a.m. Eastern Daylight Time on Thursday, August 6, ... to access the call is U.S./ Canada ...
Breaking Medicine Technology:PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 2PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 3PDL BioPharma Announces $40 Million Financing Transaction with CareView Communications 4EnteroMedics Inc. Announces Proposed Public Offering of Common Stock and Warrants 2EnteroMedics Inc. Announces Proposed Public Offering of Common Stock and Warrants 3Allergan to Host Second Quarter 2015 Earnings Conference Call and Webcast 2Allergan to Host Second Quarter 2015 Earnings Conference Call and Webcast 3
... Radiologic (vRad), a technology-enabled national radiology practice, has again ... market segment by independent research and consulting firm KLAS. ... interviews conducted by KLAS and is published in the ... Software & Professional Services report. In ...
... Reportlinker.com announces that a new market research report ... Novo Nordisk A/S: PharmaVitae Profile ... This analysis examines the historical ... prescription pharmaceutical sector. The profile encompasses global company ...
Cached Medicine Technology:Virtual Radiologic Ranked #1 for Teleradiology Services for Third Consecutive Year 2Reportlinker Adds Novo Nordisk A/S: PharmaVitae Profile 2
... third-generation allergy test , 3gAllergy is a ... provides quantitative determination of allergen-specific IgE at ... and lot-to-lot reproducibility. The assay delivers reliable ... you identify, monitor and manage patients with ...
... System is part of a series of modular ... ranging from 3.5 to 8.0 mm. Matching a ... system provides convenience and flexibility for the orthopaedic ... system may be customized using two of three ...
The DePuy ACE 8.0mm Cannulated Cancellous Screw incorporates TiMAX to provide superior strength, fatigue resistance and a lower modulus of elasticity when compared to similar stainless steel devices....
... The VersaNail System is a complete system ... to use with TTC fusion surgery. The ... specialists and integrates clinical research and engineering ... Because every patient is different, and because ...
Medicine Products: