Navigation Links
Study finds heart failure is rare among leukemia patients on imatinib
Date:9/6/2007

HOUSTON - Congestive heart failure rarely occurs among leukemia patients who take imatinib, researchers at The University of Texas M. D. Anderson Cancer Center found after an exhaustive review of the detailed medical histories of 1,276 patients who enrolled in clinical trials for the drug.

Researchers found 22 patients, or 1.7 percent, had symptoms that could have been caused by heart failure. Of those, 18 had previous medical conditions that could also cause heart failure, such as type II diabetes, hypertension, irregular heartbeat or coronary artery disease. Six had congestive heart failure before entering treatment. The results were reported in the Aug. 15 edition of the journal Blood.

"Imatinib remains a safe drug, but monitoring patients and knowing their medical histories are always important," says Jorge Cortes, M.D., senior author of the report and professor in M. D. Anderson's Department of Leukemia. "There is no current need for routine cardiac-specific monitoring of all patients taking imatinib. However, those with significant cardiac history need to be closely monitored. Patients who develop symptoms of heart failure should be evaluated carefully and treated with standard therapy."

Of the 22 patients found to have cardiovascular conditions, 11 were able to continue on imatinib for their leukemia after dose adjustments and management of the heart failure symptoms. The standard of care for treatment includes the use of beta blockers and angiotensin converting enzyme inhibitors or angiotensin receptor blockers, notes study co-author Jean-Bernard Durand, M.D., an assistant professor in M. D. Anderson's Department of Cardiology. Both classes of drugs are approved by the FDA for treatment of heart failure and recommended by the Heart Failure Society of America.

The team also found the incidence of congestive heart failure among patients receiving imatinib to be comparable to the expected incidence in the general pop
'/>"/>

Contact: Scott Merville
sdmervil@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Gene study links endometriosis, infertility
2. Study reveals how stress can make you sick
3. Study points out that HIV vaccine may not be accepted easily
4. A new study surpasses Gene Therapy Hurdle
5. Tomato Sauce reduces Cancer Risk- Study
6. A question on study of Adult Stem Cell
7. Study on obesity and heart failure
8. National Lung Study in the process
9. Marijuana gateway theory strengthened by study of twins
10. Old theory of adaptation confirmed by new study
11. Study casts doubt on keyboard ills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... (PRWEB) July 11, 2014 As reported ... Arrested For Cocaine: Are Genetics To Blame (6/30), Indino ... suspected cocaine and paraphernalia to smoke it with. His ... genetics that his son inherited from him may have ... Jr. made the news during the 1980s and 1990s ...
(Date:7/11/2014)... Organic Crop Farming in Australia ... limelight over the past decade. According to IBISWorld industry ... be an alternative food eaten only by minority groups, ... food.” Organic crop farmers have reaped the benefits of ... herbs over the past five years. Industry revenue is ...
(Date:7/11/2014)... 11, 2014 (HealthDay News) -- A new study challenges the ... good for your heart. Researchers analyzed more than 50 ... than 260,000 people. They found that those with a ... generally had healthier hearts. The gene affects how a person,s ... nausea and facial flushing. Having this variant has been shown ...
(Date:7/11/2014)... American Farmer is proud to announce ... 15, 2014, at 8:30 am ET. , In this ... which are designed and formulated for use on a ... these products help the crop realize its maximum genetic ... grown. , The show also features UniSouth Genetics, a ...
(Date:7/11/2014)... July 11, 2014 College athletes experiencing ... week of injury, but developed recurrent instability in 63% ... American Orthopaedic Society for Sports Medicine’s ( AOSSM ) ... physicians in providing the most optimal treatment plans for ... an anterior shoulder instability event, and found that 33 ...
Breaking Medicine News(10 mins):Health News:Roberty Downey's Son Arrested For Cocaine 2Health News:Organic Crop Farming in Australia Industry Market Research Report Now Available from IBISWorld 2Health News:Organic Crop Farming in Australia Industry Market Research Report Now Available from IBISWorld 3Health News:Organic Crop Farming in Australia Industry Market Research Report Now Available from IBISWorld 4Health News:A Little Alcohol May Not Be Good for Your Heart After All 2Health News:New Episode of American Farmer Featuring Sunbelt, UniSouth Genetics, and Michigan Milk Producers Association Airing on RFD-TV 2Health News:Intercollegiate Contact Athletes with Shoulder Instability Return to In-Season Sports, Study Shows 2
... HARRISBURG, Pa., Jan. 3 Consumers who,purchased or ... from,the Schumacher,s Inn in Austin, Potter County, should ... Botulism contamination, Health Secretary Dr. Calvin B.,Johnson said ... the restaurant should,immediately contact the Pennsylvania Department of ...
... (OTC,Bulletin Board: RXEI), a developer, manufacturer, and marketer ... a registration,statement covering the resale of 53,747,555 shares ... and Exchange Commission on January,2, 2008., This ... does not,represent a solicitation or offer to buy ...
... mind can affect the body,s health, researchers say , , THURSDAY, ... say they have prescribed a placebo to a patient during ... A majority of doctors in the study also said they ... accept a mind-body relationship that can affect health, the ...
... faster cancer growth and earlier death, agency says ... studies offer further evidence of the health risks posed ... U.S. officials announced Thursday. , The studies showed that ... the drugs as treatment for chemotherapy-induced anemia died sooner ...
... treated for hypothyroidism aren,t likely to drop pounds with ... the Journal of Pediatrics. The study is the first ... loss in pediatric patients., Parents of overweight children ... request thyroid tests, but, unfortunately, screening for hypothyroidism is ...
... with radiation, finding no raised risk to heart , , ... that a common but controversial treatment for prostate cancer ... of heart problems, as some specialists had feared. ... a combination of testosterone-lowering drugs and radiation therapy appeared ...
Cached Medicine News:Health News:Health Department Warns Consumers of Home-Canned Soup Linked to Potter County Restaurant 2Health News:RxElite Registration Statement Declared Effective by Securities and Exchange Commission 2Health News:Almost Half of Doctors Have Prescribed Placebos 2Health News:FDA Reports New Risks Posed by Anemia Drugs 2Health News:FDA Reports New Risks Posed by Anemia Drugs 3Health News:Thyroid treatment no 'quick fix' for weight loss in children 2Health News:Combo Therapy Cuts Prostate Cancer Death Rates 2Health News:Combo Therapy Cuts Prostate Cancer Death Rates 3
(Date:7/10/2014)...   Ventana Medical Systems, Inc.  (Ventana), a member ... into an agreement with Merck KGaA, Darmstadt, ... the United States and ... biopharmaceutical division on the development and commercialization of a ... proprietary diagnostic assays. In alignment with Merck KGaA,s strategic ...
(Date:1/15/2014)... Jan. 15, 2014 Sono-Tek Corporation (OTC BB: SOTK) today ... 30, 2013, compared to sales of $2,202,000 for the prior ... this quarter has also shown growth over the preceding quarter,s ... of this fiscal year. Markets that experienced sales increases over ...
(Date:1/15/2014)... 15, 2014 AARP Foundation today announced it has established ... from the severe cold weather that has gripped much of ... those in need; so to support these emergency relief efforts ... $250,000, which could mean up to $500,000 in aid. The ...
Breaking Medicine Technology:Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3
... Calif., Oct. 1 NeurogesX, Inc. (Nasdaq: NGSX ... novel pain management therapies, announced today that Anthony DiTonno, ... at the Fourth Annual JMP Securities Healthcare Focus Conference, ... New York City. , Mr. DiTonno and Stephen Ghiglieri, ...
... Oct. 1 The Prix Galien USA committee celebrated ... for the development and discovery of drugs and technologies ... and Veridex were honored with the 2009 Prix Galien ... and development, for treatments that could change the course ...
Cached Medicine Technology:NeurogesX to Present at JMP Securities Healthcare Focus Conference 2NeurogesX to Present at JMP Securities Healthcare Focus Conference 3Prix Galien USA Honors Innovation in Science and Biotech Industries 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: