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Study finds genetic link to human herpes susceptibility
Date:1/28/2008

nd burden of latent infection, also probably influence the frequency of HSV outbreaks.

The researchers began the study with no preconceptions about which regions of the human genome might be linked to cold sore susceptibility, Kriesel said. Therefore, the linkage with the long arm of chromosome 21 came as a surprise. We didnt start with the thought that particular genes were important in the search, he said. That helped ensure an unbiased study and led to a completely unexpected result in chromosome 21.

Now Kriesel, Hobbs, and their colleagues are looking at the six candidate susceptibility genes to find out which are related to cold sores. Three of those genes look particularly promising to study.

Finding a drug target to reduce the frequency of cold sores would be even more valuable if we could expand our study results to include genital herpes or herpes keratitis, Kriesel said, and thats something Id like to do.


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Contact: Phil Sahm
psahm@hsc.utah.edu
801-581-2517
University of Utah Health Sciences
Source:Eurekalert

Page: 1 2 3

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