Navigation Links
Study finds diabetes does not increase risk of total knee surgical complications
Date:2/28/2013

PASADENA, Calif., Feb. 27, 2013 Patients with diabetes who undergo total knee replacement surgery do not have increased risk of surgical complications compared to those patients without diabetes, according to a Kaiser Permanente study published today in The Journal of Bone and Joint Surgery.

Researchers studied the electronic health records of more than 40,000 patients who had a first-time knee replacement from January 1, 2001 through December 31, 2009. Of the patients studied, 12.5 percent had controlled diabetes, 6.2 percent had uncontrolled diabetes and 81.3 percent did not have diabetes. In contrast to the findings of previous studies, researchers on this study found those with controlled and uncontrolled diabetes who underwent a total knee replacement were at no increased risk of complications such as follow-up surgery (also known as revision arthroplasty), deep infection, or blood clots in the legs or lungs, when compared to patients without diabetes.

"We are fortunate to do our research in a real-world setting that helps us to find real-world solutions for our patients," said Annette L. Adams, PhD, MPH, of the Kaiser Permanente Southern California Department of Research & Evaluation. "This current study suggests that patients with diabetes who have higher glucose levels may not be at greater risk of poor surgical outcomes. This finding will help physicians and their patients with diabetes make better informed decisions about total knee replacement as an option."

Adams also noted that one of the elements that differentiated this study from previous research was that the Kaiser Permanente patients with diabetes had better glycemic control than previous study populations. "We have good quality of care, and good chronic disease management," Adams said, "and in this setting, glycemic control had little impact on the outcome of total knee replacement surgery."

The study also found that among the approximately 28 percent of patients who did experience adverse outcomes in the year after surgery, 27.1 percent were rehospitalized for any reason, 1.1 percent underwent follow-up surgery, 1 percent had a heart attack, 0.7 percent developed a deep infection while 0.5 percent had blood clots in the legs and lungs within the first 90 days after surgery.

"While this study puts us one step closer to understanding diabetes-related complications associated with surgical procedures, more research is needed to determine what aspects of diabetes are associated with adverse outcomes," said Robert Namba, MD, Department of Orthopedic Surgery at Kaiser Permanente Southern California. "It is important to note that patients with diabetes remain at high risk of a number of poor health outcomes affecting many organ systems and clinicians should continue to review all available information about the overall health and stability of these vulnerable patients."

The study was sponsored by Kaiser Permanente's Center for Effectiveness and Safety Research, The Center facilitates inter-regional research conducted by the research programs in each of Kaiser Permanente's eight regions (Colorado, Georgia, Hawaii, Mid-Atlantic States, Northern California, Northwest, Ohio, and Southern California). Through investments in infrastructure and specific projects, the center takes advantage of Kaiser Permanente's talented research teams, rich data assets, and integrated delivery system to contribute to the knowledge base in comparative effectiveness and safety.

"This work illustrates how Kaiser Permanente is realizing the promise of a learning healthcare organization," said Elizabeth McGlynn, PhD, director of the Center for Effectiveness and Safety Research. "We are bringing together our clinical leaders and the Kaiser Permanente research community to answer questions that are critical for ensuring high-quality patient care."

The study was conducted using the Kaiser Permanente Total Joint Replacement Registry, which now has more than 160,000 total joint arthroplasty procedures registered. Since its inception in 2001, Kaiser Permanente's registry has helped health care providers identify clinical best practices, evaluate and monitor patient outcomes and risk factors associated with revision surgeries, and assess the clinical effectiveness of implants. Developed in association with Kaiser Permanente's surgeons, the registry's data is collected prospectively through standardized documentation by surgeons and supplemented by the organization's electronic health records.

Kaiser Permanente's implant registries, which include the Total Joint Replacement Registry, recently won the 2012 annual John M. Eisenberg Patient Safety and Quality Award, sponsored by The National Quality Forum and The Joint Commission. These registries are models of integration across medical centers in nine states and they represent strong partnerships among health plan administration, hospitals, and physician medical groups united to improve the quality of care for patients.


'/>"/>

Contact: Jacqueline Brown
jacqueline.brown@golinharris.com
415-318-4361
Kaiser Permanente
Source:Eurekalert

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... February 08, 2016 , ... Delta Dental of California and its ... cancer. , Gary D. Radine, who recently retired as president and CEO of Delta ... 2015 CEO of the Year , helped lead the effort to raise funds ...
(Date:2/8/2016)... ... February 08, 2016 , ... Eating ... a significant number of women and men with eating disorders report a history ... best predicts the development of an eating disorder. , At the 2016 ...
(Date:2/8/2016)... ... February 08, 2016 , ... GrassrootsHealth published data from ... type 2 diabetes in the GrassrootsHealth cohort with substantially higher vitamin D levels ... in public health,” states Carole Baggerly, Director of GrassrootsHealth, “the safety and ...
(Date:2/8/2016)... ... February 08, 2016 , ... Joshua Rosenthal, PhD, Chief Scientific ... can use newly released government data on populations and physicians to better calculate ... capture the value they create to succeed in new economic models for value ...
(Date:2/8/2016)... , ... February 08, 2016 , ... ... only four states in the U.S. require dental technicians to be certified or ... the dental industry, NADL created the “What’s In Your Mouth?” campaign to inform ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016  Echo Therapeutics, ... device company focused on non-invasive continuous glucose ... today announced that it will host a ... 17, 2015 at 9:00 a.m. Eastern Time ... its corporate strategy, advancements in its CGM ...
(Date:2/8/2016)... , Feb. 8, 2016 ... the "Global Skin Protective Equipment Market 2016-2020" ... --> http://www.researchandmarkets.com/research/fqx6nz/global_skin ) has announced the addition ... 2016-2020" report to their offering. ... ) has announced the addition of the ...
(Date:2/8/2016)... , Feb. 8, 2016   HighPoint ... November Research Group (NRG),s pharmacovigilance technology services division.  ... consulting services and an Oracle Argus Specialized partner, ... to Life Sciences companies. --> ... expands HighPoint,s life sciences capabilities and provides a ...
Breaking Medicine Technology: