Navigation Links
Study finds cutting colonoscopy preparation from 2 days to 1 day just as effective
Date:5/4/2010

(PHILADELPHIA) Researchers at Thomas Jefferson University have found that colonoscopy preparation drugs administered the same day as the procedure are equally effective to those given the night before and the morning of the procedure, but result in less complaints of side effects such as abdominal pain, sleep loss and workday interference.

The randomized, single blind study, compared results between 116 colonoscopy patients given a split dosage of colon preparation the night before and morning of their colonoscopy and those given the colonoscopy preparation solely the morning of their colonoscopy. The study shows that both treatments are clinically equal. Primary Investigator David Kastenberg, M.D., department of Gastroenterology and Hepatology at Jefferson Medical College of Thomas Jefferson University and his co-authors present their findings in the current online edition of the American Journal of Gastroenterology.

"The most important thing to consider during a colonoscopy are clear images," said Kastenberg. "During the procedure I want to be able to have the best view to ensure that nothing is missed and all abnormalities are scrutinized. That's why the colon prep is so important. For years patients have been taking the colon prep solution the night before and had successful colonoscopies the following day but had to endure numerous side effects. Recently, the American College of Gastroenterology endorsed split dosing, which means patients need to experience all the side effects of a colon prep both at night and on the morning of the colonoscopy. What we looked at was can we administer the colon prep the same day and get equal results without the side effects? The answer is yes. The images are just as good when giving the colon prep the day of the procedure than they are when giving the colon prep as a split dose on both days, while reducing and in some cases eliminating the side effects."

Of the 116 patients studied 62 received the prep in the morning against 54 receiving it the night before. The colon images were adequate in both groups at well over 90 percent. Polyp detection was actually found to be greater in the morning colon prep group. Overall adverse effects were found not to be significantly different between the two groups.

"The real advantage of the morning prep is it has less interference on the patients quality of life," said Kastenberg. "Many patients complain about trouble sleeping after taking the colon prep the night before. Also this lessens the impact on work-related function the day prior. Perception is also key. Patients may well tolerate the colon prep and procedure better if it's a one day event versus two."

Every year over 14 million Americans have colonoscopies. The procedure is a highly effective way of detecting pre-cancerous polyps. Unchecked these polyps can lead to colon cancer which is one of the top three leading causes of cancer-related deaths among men and women in the United States.

"Colon cancer is a common and preventable disease, but only half of eligible patients undergo screening," said Kastenberg. "Anything we can do that provides additional comfort without affecting results should be considered. If we can make the patient's experience easier and demonstrate to future patients that the procedure from beginning to end will only last one day, then maybe some of the over 42 million Americans who should be screened, but aren't, will come forward and we might be able to save some lives."


'/>"/>

Contact: Richard Cushman
richard.cushman@jefferson.edu
215-955-2240
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Casual Sex Doesnt Cause Emotional Damage: Study
2. Study Finds Possible Explanation for the Link Between Infertility and Breast/Ovarian Cancer Risks
3. Screening for Spinal Muscular Atrophy Not Cost-Effective: Study
4. New study finds possible source of beta cell destruction that leads to Type 1 diabetes
5. New Study Demonstrates Novel Use of Metabolic Imaging to Locate Sperm in Infertile Men -- Non-Invasive Imaging Procedure May Replace Invasive Techniques such as Testicula
6. Risk of stroke lower for recent Ontario immigrants: study
7. Definitive study confirms chemo benefit in postmenopausal breast cancer
8. Experimental stem cell treatment arrests acute lung injury in mice, study shows
9. Violence is part of the job say nurses as study shows only 1 in 6 incidents are reported
10. Controversial Autism Study Retracted by Medical Journal
11. Study Reveals Impact Of Health Insurance On Hispanics' Attitudes Towards Healthcare Providers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... City, Oklahoma (PRWEB) , ... June 25, 2016 ... ... helping both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic ... the Oklahoma City area —Johnson is one of the first doctors to perform ...
(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Story Highlights: ... the health care industry is causing providers to review ... Deloitte offers a suite of solutions for health care ... cost optimization: labor resource analysis, revenue cycle optimization and ... outcomes and better economics ...
(Date:6/24/2016)... Calif. , June 24, 2016  Global ... a biopharmaceutical company developing novel therapeutics for the ... needs, today announced the closing of its previously ... common stock, at the public offering price of ... the offering were offered by GBT. GBT estimates ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
Breaking Medicine Technology: