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Study finds close linkage between a rare, deadly lung condition and blood cell abnormalities
Date:2/28/2011

ays a crucial role in the formation of new blood vessels by recruiting progenitor cells from the circulation. Because HIF, EPO, and HGF can affect bone marrow progenitors, it appeared that there may be an abnormal feedback loop connecting blood and lung cell behavior. The presence of such an abnormal loop could provide a previously unrecognized opportunity for intervening in PAH, depending on the results of further investigation.

"Continued research will help us gain a better understanding of the level of cross-influence between these two conditions in order to improve treatment strategies and, ultimately, the quality of patient care," said Samar Farha, MD, co-author of the study and staff physician in the Respiratory Institute at the Cleveland Clinic.


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