Navigation Links
Study finds biologic therapies for rheumatoid arthritis not associated with increased cancer risk
Date:9/4/2012

HOUSTON Biologic therapies developed in the last decade for rheumatoid arthritis are not associated with an increased risk of cancer when compared with traditional treatments for the condition, according to new research from The University of Texas MD Anderson Cancer Center.

The study, published in The Journal of the American Medical Association (JAMA), is the largest systematic review evaluating the risk of developing any malignancy among rheumatoid arthritis patients using approved biologic response modifiers (BRMs), several of which include tumor necrosis factor (TNF) inhibitors. Since 2005, conflicting data has associated TNF inhibitors with an increased risk of developing certain types of malignancies. Because of increased cases of spontaneous lymphoma in children and adolescents, the current US Food and Drug Administration warning label notes the risk of malignancy for all TNF inhibitors.

"These results are reassuring for patients considering biologic therapies for their disease," says senior author Maria E. Suarez-Almazor, M.D., professor in the Department of General Internal Medicine at MD Anderson. "Patients are understandably concerned when treatments are linked to cancer risk. With this knowledge, clinicians can effectively demonstrate that the benefits of BRMs far outweigh the risk."

Rheumatoid arthritis affects approximately one percent of the population and can lead to significant morbidity, joint deformity and impaired quality of life. Traditional treatments for rheumatoid arthritis include disease-modifying anti-rheumatic drugs (DMARDs), like methotrexate, and anti-inflammatory medications.

BRMs are prescribed as a second line of treatment if the initial DMARDs fail. BRMs target molecules on cells of the immune system and joints, and the products that are secreted in the joints, all of which can cause inflammation and joint destruction. Between 25 and 56 percent of patients use BRMs to treat th
'/>"/>

Contact: Julie Penne
jpenne@mdanderson.org
713-792-0622
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Little evidence of health benefits from organic foods, Stanford study finds
2. Combat Stress Linked to Brain Changes in Study
3. Organic Foods Not Healthier or More Nutritious, Study Says
4. Obesity Might Lower Teens Thinking Skills, Study Suggests
5. Study details bullying involvement for adolescents with autism spectrum disorder
6. Study suggests possible association between cardiovascular disease, chemical exposure
7. Study examines association between Parkinson disease, cancer
8. Mathematics or memory? Stanford study charts collision course in brain
9. Few Doctors Discuss Exercise With Cancer Patients: Study
10. Study explores why children with asthma are more likely to be bullied
11. Marathons Safe for Aging Boomers, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... Abilene, Texas (PRWEB) December 26, 2014 Yisrayl ... has written an open letter in light of the Ferguson, ... year history of civil unrest and explains why it has ... the reason mankind was even created. He says there is ... in detail. Yisrayl also says there is a set of ...
(Date:12/26/2014)... 2014 “Many people become overwhelmed by ... claim issues and phone calls with insurance companies,” The ... featuring their free eBook on pedestrian and bicycle ... pedestrian and bicycle auto accident claims assures the injured ... of professionally handling their case while they focus on ...
(Date:12/26/2014)... DW-InductionHeating.com (DaWei Induction Heating Co.) is a ... producing and marketing of a series of induction heating ... new series of induction brazing equipments . , ... induction brazing refers to the joining of two ... heat. The manager says that there are fundamental differences ...
(Date:12/25/2014)... This is a professional and in-depth study on ... a focus on the Chinese market. The report provides ... manufacturers and is a valuable source of guidance and ... This report provides a basic overview of the industry ... part, the report presents the company profile, product specifications, ...
(Date:12/25/2014)... TX (PRWEB) December 26, 2014 The ... to 2023” focuses on the current treatment landscape, unmet ... cancer market. TS-1 is an anti-cancer drug which is ... orally and is also used for treating gastric cancer ... and otastat potassium. The drug was first approved in ...
Breaking Medicine News(10 mins):Health News:Yisrayl Hawkins Pleads for Peace in Ferguson and Beyond in New Open Letter 2Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Induction Brazing Equipment Series From DaWei Induction Heating Co., A Reliable Supplier Of Induction Heating Equipment 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3
... According to a recent Washington Post study, approximately 20% ... psychologically damaged. Among them are a substantial number with ... suicide among PTSD sufferers has become unacceptable to Army ... research from Tel Aviv University, however, doctors will now ...
... , , , ... NEW YORK, Sept. 2 Today, Tim Gunn, television host and ... officer of Liz Claiborne, Inc., is hosting the Ad dressing Psoriasis(TM) ... fashion show recognizes people with moderate to severe plaque psoriasis who have ...
... fibrillation patients drink lots of coffee, don,t eat right, ... People who drink lots of coffee but who don,t ... atrial fibrillation, a new study shows. , Italian researchers ... heart arrhythmia to supply information about their dietary habits, ...
... , , , ... FTER), which, through its ABTTC Inc. division, provides drug and ... with the highest levels of accreditation, announced today that its ... Gaskin on the Company,s recent successes, management team and shareholder ...
... Fla., Sept. 2 Cinergy Health, a nationwide provider of Limited ... chief medical director. As Cinergy Health,s chief medical director, Dr. Lewin ... studies and emerging research to the doctor patient relationship and health ... have Dr. Lewin join the Cinergy Health team," said Daniel Touizer, ...
... , INDIANAPOLIS, Sept. 2 Eli Lilly and Company ... given the Epsilon "Star of Highest Magnitude" Award and has been ... Data Processing Associates (BDPA) and WorkplaceDiversity.com. The Epsilon Award is ... a workplace and environment that supports the advancement of African-Americans in ...
Cached Medicine News:Health News:Keeping the suicidal soldier alive 2Health News:Tim Gunn Hosts Addressing Psoriasis(TM) Fashion Show to Raise Awareness of Psoriasis 2Health News:Tim Gunn Hosts Addressing Psoriasis(TM) Fashion Show to Raise Awareness of Psoriasis 3Health News:Tim Gunn Hosts Addressing Psoriasis(TM) Fashion Show to Raise Awareness of Psoriasis 4Health News:Tim Gunn Hosts Addressing Psoriasis(TM) Fashion Show to Raise Awareness of Psoriasis 5Health News:Caffeine Without Healthy Diet Linked to Heart Risk 2Health News:Forterus Inc. Treatment Centers Showing Consistent, Sustainable Growth; CEO Paul Howarth Interviewed 2Health News:Cinergy Health Names Dr. Margaret Lewin Chief Medical Director 2Health News:Lilly Named Best Company for Blacks in Technology 2
(Date:12/22/2014)... 22, 2014 Apnea Sciences ( www.apneasciences.com ) ... Aliso Viejo , California.  Jimmy ... tremendous growth and worldwide expansion, a new facility with ... the anti snore cure have exceeded our expectations and ... are now in 23 countries and will be increasing ...
(Date:12/22/2014)... Dec. 22, 2014 Research and Markets ... of the "Investment Analysis of the US ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... US medical device sector identifies the key trends ... capital investments, and mergers and acquisitions. ...
(Date:12/22/2014)... and STOCKHOLM , Dec. ... (Sobi) and partner Auxilium Pharmaceuticals, Inc. today announced that ... of the European Medicines Agency (EMA) has adopted a ... histolyticum) for the treatment of adult men with Peyronie,s ... at least 30 degrees at the start of therapy. ...
Breaking Medicine Technology:Investment Analysis of the US Medical Device Sector 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 2Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 3Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 4Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 5Sobi's Xiapex receives positive opinion by CHMP for the treatment of Peyronie's disease 6
... 1 /PRNewswire/ - ImmunoVaccine Technologies, (IVT),patented depot ... with single-dose efficacy achieved in therapeutic,cancer and ... of this,research will be presented October 4th ... from the University of Miami will also ...
... testing give women answers about their ... ... U.S. Cancer,Statistics Working Group (2007), an estimated 182,460 new cases of breast,cancer ... resulting in the earlier detection of the disease when it is,more easily ...
Cached Medicine Technology:ImmunoVaccine Technologies' DepoVax(TM) Shows Positive Results for Cancer and Infectious Diseases 2Good Samaritan Hospital Launches High Risk Breast Cancer Program at Good Samaritan North Health Center 2Good Samaritan Hospital Launches High Risk Breast Cancer Program at Good Samaritan North Health Center 3Good Samaritan Hospital Launches High Risk Breast Cancer Program at Good Samaritan North Health Center 4
The latex-free, PVC-free Antibacterial Hydro Personal catheter combines two remarkable innovations into one exclusive catheter that delivers an antibacterial agent while providing the virtually frict...
The Antibacterial Personal Catheter® features a unique silicone composition that provides an antibacterial coated soft outer layer of silicone combined with a firm inner layer....
The Uro San® Plus male external catheter is a latex catheter with a double-sided adhesive and Shield Skin Protective Dressing....
... Mentor Freedom Pak Seven Starter ... week's supply of Freedom Clear ... all 100% latex-free ... for your convenience and comfort. ...
Medicine Products: