Navigation Links
Study expected to boost research for hearing and balance therapies
Date:9/25/2007

CHARLOTTESVILLE, VA (September 25, 2007) Birds, fish and amphibians can do something that humans and other mammals generally cannot: re-grow damaged or lost inner ear hair cells.

Loss of these cells causes hearing deficiencies and disabling balance problems in an estimated 250 million people worldwide. Despite the compelling need for new treatments, research and development efforts have been hindered by the relative scarcity of inner ear hair cells. A new study by neuroscientists at the University of Virginia Health System promises to boost cell supplies and accelerate therapeutic advancements.

Humans and other mammals only produce hair cells before birth and lose them over time. People lose hair cells in their inner ear for many reasons trauma, infections, drug toxicity, genetic disorders and aging, explains Jeffrey T. Corwin, PhD, professor of Neuroscience at the University of Virginia Health System and co-author of a study published this month in the Proceedings of the National Academy of Sciences (PNAS).

Sensory cells in the inner ear have hair bundles that detect the presence of sound. These cells are not only essential for hearing but help to control reflexes that stabilize our visual world, posture and movements. While hair cell loss remains clinically irreversible in humans, related research indicates that the potential for regeneration lies in the supporting cells of our balance organs.

In the UVa study, Dr. Corwin and his co-author, Dr. Zhengqing Hu, describe a new method of growing inner ear hair cells in the laboratory. They isolated cells from the inner ears of chicken embryos and perpetuated the cells in tissue culture. The researchers grew the cultures over several months, froze them and then thawed and greatly expanded the numbers of cells. Then, they discovered methods for causing hair cells to differentiate within the growing cultures.

We produced the equivalent of test-tube inner ear hair cells, Dr. Hu says.

The methods developed at UVa are expected to provide a new, reliable source of cells and expand research efforts. Without adequate supplies of hair cells, it has been difficult to study factors that promote and inhibit their growth, explains Dr. Corwin. We hope our findings increase the scope and pace of inner ear research that is ultimately designed to benefit of millions of people around the world who are affected by hearing and balance impairments.


'/>"/>

Contact: Ellen McKenna
ecm6n@virginia.edu
434-982-4490
University of Virginia Health System
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/24/2017)... ... August 24, 2017 , ... DrinkingTutors.com, a startup focused on ... tutorials, or ‘drinktorials,’ are mailed directly to teenagers’ homes every week. , ... their teenagers avoid the serious risks associated with binge drinking in high school, ...
(Date:8/23/2017)... ... ... Drs. Steven White and Brad Haines are pleased to announce an exclusive ... offer, valued at more than $300 per year, new patients can enjoy a lifetime ... a complimentary professional whitening procedure. , Stained or yellowed tooth enamel is common ...
(Date:8/23/2017)... , ... August 23, 2017 , ... Nightingale College continues ... Give Back Day is a time Nightingale College dedicates to serving and volunteering for ... thrive on donations and volunteers or those that need a little extra help. ...
(Date:8/23/2017)... (PRWEB) , ... August 23, 2017 , ... ... vans, announced today that has been named to the 2017 Inc. 500|5000, an ... based on a three-year growth rate of 139 percent, marking the twelfth year ...
(Date:8/23/2017)... ... August 23, 2017 , ... ... (SNAC) is holding an inaugural State of the Science Symposium in partnership ... Wednesday, Sept. 20, 2017. , This symposium provides a forum for global leaders ...
Breaking Medicine News(10 mins):
(Date:8/23/2017)... , Aug. 23, 2017 DarioHealth Corp. ... with mobile health and big data solutions, announced ... placement offerings with domestic and non-U.S. investors for ... stock and shares of the Company,s newly designated ... placement offerings. Current shareholders accounted for 58% of ...
(Date:8/17/2017)... MJAC2017 , the premier cannabis event devoted to retail ... leading lineup. MJAC2017 is proud to ... in the development of pharmaceutical and consumer products, will be ... Green Organic Dutchman are gold sponsors for the event, joined ... ...
(Date:8/15/2017)...   Mostyn Law and Gulf Coast Regional Blood Center ... . The Mostyn Law family has had 3 members ... why Mostyn Law is partnering with Gulf Coast Regional ... appreciation. Blood supplies are running low. Gulf Coast Regional ... needs in August. That is why the blood center reached out ...
Breaking Medicine Technology: