Navigation Links
Study expected to boost research for hearing and balance therapies
Date:9/25/2007

CHARLOTTESVILLE, VA (September 25, 2007) Birds, fish and amphibians can do something that humans and other mammals generally cannot: re-grow damaged or lost inner ear hair cells.

Loss of these cells causes hearing deficiencies and disabling balance problems in an estimated 250 million people worldwide. Despite the compelling need for new treatments, research and development efforts have been hindered by the relative scarcity of inner ear hair cells. A new study by neuroscientists at the University of Virginia Health System promises to boost cell supplies and accelerate therapeutic advancements.

Humans and other mammals only produce hair cells before birth and lose them over time. People lose hair cells in their inner ear for many reasons trauma, infections, drug toxicity, genetic disorders and aging, explains Jeffrey T. Corwin, PhD, professor of Neuroscience at the University of Virginia Health System and co-author of a study published this month in the Proceedings of the National Academy of Sciences (PNAS).

Sensory cells in the inner ear have hair bundles that detect the presence of sound. These cells are not only essential for hearing but help to control reflexes that stabilize our visual world, posture and movements. While hair cell loss remains clinically irreversible in humans, related research indicates that the potential for regeneration lies in the supporting cells of our balance organs.

In the UVa study, Dr. Corwin and his co-author, Dr. Zhengqing Hu, describe a new method of growing inner ear hair cells in the laboratory. They isolated cells from the inner ears of chicken embryos and perpetuated the cells in tissue culture. The researchers grew the cultures over several months, froze them and then thawed and greatly expanded the numbers of cells. Then, they discovered methods for causing hair cells to differentiate within the growing cultures.

We produced the equivalent of test-tube inner ear hair cells, Dr. Hu says.

The methods developed at UVa are expected to provide a new, reliable source of cells and expand research efforts. Without adequate supplies of hair cells, it has been difficult to study factors that promote and inhibit their growth, explains Dr. Corwin. We hope our findings increase the scope and pace of inner ear research that is ultimately designed to benefit of millions of people around the world who are affected by hearing and balance impairments.


'/>"/>

Contact: Ellen McKenna
ecm6n@virginia.edu
434-982-4490
University of Virginia Health System
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 27, 2016 , ... Quality metrics ... yet in many ways they remain in the eye of the beholder, according to ... a publication of The American Journal of Managed Care. For the full issue, ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016   Bay Area Lyme Foundation ... Dean Center for Tick Borne Illness , Harvard ... MIT Hacking Medicine, University of California, Berkeley, and ... the five finalists of Lyme Innovation , ... than 100 scientists, clinicians, researchers, entrepreneurs, and investors ...
(Date:6/24/2016)... CLEMENTE, Calif. , June 24, 2016  American Respiratory Labs ... company, is now able to perform sophisticated lung assessments in patients, ... Technologies , Inc. Patients are no longer limited ... ndd,s EasyOne PRO ® , ARL patients like Jeanne R. of ... done in the comfort of her own home. ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: