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Study examining large-scale data of double balloon enteroscopy shows it is safe and effective
Date:9/26/2011

bleeding was the most common indication (62.5 percent), followed by symptoms and signs only (7.9 percent), small intestine obstruction (5.8 percent), and Crohn's disease (5.8 percent). The pooled detection rates were as follows: suspected mid-gastrointestinal bleeding (68.1 percent), symptoms and signs only (68 percent), Crohn's disease (53.6 percent), and small intestine obstruction (63.4 percent). The overall detection rate was 85.8 percent. Inflammatory lesions (37.6 percent) and vascular lesions (65.9 percent) were the most common findings, respectively, in suspected mid-gastrointestinal bleeding patients of Eastern and Western countries. The pooled total enteroscopy rate was 44 percent by combined or antegrade-only approach. The pooled minor and major complication rates were 9.1 percent and 0.72 percent, respectively.

The researchers concluded that the detection rate and complication rate of DBE are acceptable. They found that DBE is a valuable modality, with a pooled detection rate of 68.1 percent for all small intestinal disease. Inflammatory lesions and vascular lesions are the most common findings in patients with suspected mid-gastrointestinal bleeding in Eastern and Western countries, respectively, according to DBE. Although DBE failed to identify a proportion of lesions, they consider that the performance of DBE is acceptable because the symptoms of a significant proportion of patients without positive findings would not recur during follow-up. They noted that DBE is considered to be a safe procedure with few complications, most of which are minor.

In an accompanying editorial, Andrew S. Ross, MD, Digestive Disease Institute, Virginia Mason Medical Center, Seattle, Wash., stated, "we finally have composite large-scale data to support what we have suspected - DBE performed in appropriately selected individuals is a highly useful and extremely safe clinical tool that can be used for a variety of indications for deep enteroscopy. Although
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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