Navigation Links
Study examines the effect of epilepsy on the aging
Date:4/16/2008

Madison, Wis. April 16, 2008 An article published in the May 2008 issue of Epilepsia calls attention to the lack of knowledge regarding cognitive aging in chronic epilepsy patients. For persons with chronic epilepsy, little is known about the impact of aging on the course of cognitive and brain health, the prevalence of clinical disorders of aging (mild cognitive impairment, dementia), or the disease burdens and risk factors associated with abnormal cognitive and brain aging. The study presents data that suggest several reasons for concern.

Numerous cognitive deficits, neuroimaging abnormalities and psychiatric comorbidities have been well characterized in younger persons with chronic epilepsy, with evidence of progression of these problems in some patients by middle age. People with chronic epilepsy have been exposed to several influences that may place them at increased risk for accelerated cognitive and brain aging, including: treatment with medications now known to adversely affect cholesterol, folate and glucose metabolism; increased rates of vascular disease risk factors; altered lifestyles that include decreased social interaction and physical inactivity; and elevated inflammatory markers.

The cognitive status of persons who have lived with epilepsy for a long time is unclear, says Bruce P. Hermann, lead author of the study. Because persons with epilepsy carry other risk factors for abnormal cognitive and brain aging, there should be great concern regarding the lack of knowledge about their cognitive and brain status in older years.

Previous research has identified numerous risk factors for abnormal cognitive aging and dementia in the general population, including vascular, inflammatory and lifestyle factors. Many of these factors are overrepresented in epilepsy, but not examined in relationship to cognitive and brain aging in epilepsy. This oversight is important given the epidemiological evidence that risk exposure and cognitive abnormalities in midlife represent critical predictors of eventual abnormal cognitive and brain aging.

If these factors exert comparable effects in people with chronic epilepsy, the management of epilepsy must be expanded to aggressively address critical risk factors in order to protect and promote cognitive and brain health, says Hermann.


'/>"/>

Contact: Sean Wagner
swagner@bos.blackwellpublishing.com
781-388-8550
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Study shows pine bark naturally reduces osteoarthritis
2. Study Shows Pine Bark Naturally Reduces Osteoarthritis
3. Study suggests too much screen time and not enough physical activity may lead to childhood obesity
4. St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia
5. UAB study shows investigational drug may treat biliary cancers
6. Study shows that high-dose, high-frequency interferon produces no additional benefit
7. Study finds media coverage of breast cancer focuses too little on prevention
8. USC study finds evidence of gender-related differences in development of colon cancer
9. New study in JCSM finds that obesity can predict upper airway obstruction amongst children
10. Study shows increase of hip and knee replacements in the US
11. Study shows decline in work disability due to rheumatoid arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... 2016 , ... LaserShip, a regional parcel carrier that services the eastern U.S., ... last Friday in order to aid in the Flint water crisis. In 2014, LaserShip ... located in Clio, only 15 miles away from Flint. , “We have deep roots ...
(Date:2/10/2016)... ... February 10, 2016 , ... Western University of Health ... to the developmentally disabled in the Coachella Valley. , The two entities, through ... at 71-949 Highway 111, Suite 100-B, in Rancho Mirage, California. The new site ...
(Date:2/10/2016)... ... ... As part of its ongoing series of aquatic therapy related webinars, HydroWorx is ... expert and thoughtful presentation to give attendees a better sense of how to use ... to attend, but registration is required. , Rehabilitation of Offensive Lineman Utilizing ...
(Date:2/10/2016)... ... February 10, 2016 , ... Intermedix announced on ... Medicine , an emergency medicine professional association, to support the organization's newly established ... American Academy of Emergency Medicine, or AAEM, seeks to empower emergency physicians to ...
(Date:2/10/2016)... TX (PRWEB) , ... February 10, 2016 , ... ... commencement of a master charity program created to assist the local community. Pledging ... with community leaders and nonprofit organizations in the area. Their goal is to ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Biotechnology Inc., spurred by a major "team investment" by Bruce Montgomery , one of this ... A-Round, according to CEO Leen Kawas , PhD. ... ... ... Kawas said the round was intended ...
(Date:2/11/2016)... CARLSBAD, Calif. , Feb.11, 2016  Ionis Pharmaceuticals, Inc. ... a live webcast on Thursday, February 25 at 11:30 a.m. ... on pipeline and business progress. www.ionispharma.com . ... at the same address. --> www.ionispharma.com . A ... the same address. --> Interested parties may listen ...
(Date:2/11/2016)... -- Indiso ltd , a medical technology company ... respiratory diseases announced today positive results in its clinical ... patients show improvements in respiratory functions and other clinical ... Upper and lower respiratory tract diseases and allergy ... reached epidemic level. Increasing number of studies however show ...
Breaking Medicine Technology: