Navigation Links
Study examines the effect of epilepsy on the aging
Date:4/16/2008

Madison, Wis. April 16, 2008 An article published in the May 2008 issue of Epilepsia calls attention to the lack of knowledge regarding cognitive aging in chronic epilepsy patients. For persons with chronic epilepsy, little is known about the impact of aging on the course of cognitive and brain health, the prevalence of clinical disorders of aging (mild cognitive impairment, dementia), or the disease burdens and risk factors associated with abnormal cognitive and brain aging. The study presents data that suggest several reasons for concern.

Numerous cognitive deficits, neuroimaging abnormalities and psychiatric comorbidities have been well characterized in younger persons with chronic epilepsy, with evidence of progression of these problems in some patients by middle age. People with chronic epilepsy have been exposed to several influences that may place them at increased risk for accelerated cognitive and brain aging, including: treatment with medications now known to adversely affect cholesterol, folate and glucose metabolism; increased rates of vascular disease risk factors; altered lifestyles that include decreased social interaction and physical inactivity; and elevated inflammatory markers.

The cognitive status of persons who have lived with epilepsy for a long time is unclear, says Bruce P. Hermann, lead author of the study. Because persons with epilepsy carry other risk factors for abnormal cognitive and brain aging, there should be great concern regarding the lack of knowledge about their cognitive and brain status in older years.

Previous research has identified numerous risk factors for abnormal cognitive aging and dementia in the general population, including vascular, inflammatory and lifestyle factors. Many of these factors are overrepresented in epilepsy, but not examined in relationship to cognitive and brain aging in epilepsy. This oversight is important given the epidemiological evidence that risk exposure and cognitive abnormalities in midlife represent critical predictors of eventual abnormal cognitive and brain aging.

If these factors exert comparable effects in people with chronic epilepsy, the management of epilepsy must be expanded to aggressively address critical risk factors in order to protect and promote cognitive and brain health, says Hermann.


'/>"/>

Contact: Sean Wagner
swagner@bos.blackwellpublishing.com
781-388-8550
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Study shows pine bark naturally reduces osteoarthritis
2. Study Shows Pine Bark Naturally Reduces Osteoarthritis
3. Study suggests too much screen time and not enough physical activity may lead to childhood obesity
4. St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia
5. UAB study shows investigational drug may treat biliary cancers
6. Study shows that high-dose, high-frequency interferon produces no additional benefit
7. Study finds media coverage of breast cancer focuses too little on prevention
8. USC study finds evidence of gender-related differences in development of colon cancer
9. New study in JCSM finds that obesity can predict upper airway obstruction amongst children
10. Study shows increase of hip and knee replacements in the US
11. Study shows decline in work disability due to rheumatoid arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... April 24, 2017 , ... ... opioid overdose deaths now claim the lives of 62 Americans each day.(1) Yet ... against drug manufacturers, distributors, pharmacies and prescribers by more than half.(2) Novus ...
(Date:4/24/2017)... ANGELES, CA (PRWEB) , ... April 24, 2017 , ... ... picture is worth a thousand words. The good news for single women is that ... for Attraction," which is available on April 25th. Joan's insight, personal experiences and sparkling ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... “Reflections of ... to God. “Reflections of God’s Work” is the creation of published author, Jerri Broglin, ... God’s comfort. , “I believe this a great eye-opener for those searching for ...
(Date:4/24/2017)... WA (PRWEB) , ... April 24, 2017 , ... ... leading lifestyle brands, work wear distributors and International relief organizations across the globe ... The company also offers lifestyle and work wear collections via insectshield.com . ...
(Date:4/22/2017)... ... April 22, 2017 , ... Ecommerce sales have grown ... estimated to be $394.9 billion. The consequences of rapid innovation and growth are ... limits of technology, it is every business and individual’s job to give something back ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 2017 Companion animal ... in pets such as canine, avian and feline. ... types such as Attenuated Live Vaccines, Conjugate Vaccines, ... and Recombinant Vaccines. Attenuated live vaccines are derived ... which have been weakend under laboratory conditions. Conjugate ...
(Date:4/18/2017)... 18, 2017 Cogentix Medical, Inc. (NASDAQ: CGNT), ... Urology, Uro/Gyn and Gynecology markets with innovative and proprietary ... ended March 31, 2017 after the market close on ... will host a conference call and webcast to discuss ... 2, 2017 at 4:30 p.m. Eastern Time (3:30 p.m. ...
(Date:4/18/2017)... , April 18, 2017  Socionext Inc. and ... started in 2016, in which Socionext extracts and ... The companies achieved initial results in reading ultrasound ... Artificial Brain SOINN. The results will be introduced ... April 19-21, at booths 4505 & 4507. ...
Breaking Medicine Technology: