Navigation Links
Study examines the effect of epilepsy on the aging
Date:4/16/2008

Madison, Wis. April 16, 2008 An article published in the May 2008 issue of Epilepsia calls attention to the lack of knowledge regarding cognitive aging in chronic epilepsy patients. For persons with chronic epilepsy, little is known about the impact of aging on the course of cognitive and brain health, the prevalence of clinical disorders of aging (mild cognitive impairment, dementia), or the disease burdens and risk factors associated with abnormal cognitive and brain aging. The study presents data that suggest several reasons for concern.

Numerous cognitive deficits, neuroimaging abnormalities and psychiatric comorbidities have been well characterized in younger persons with chronic epilepsy, with evidence of progression of these problems in some patients by middle age. People with chronic epilepsy have been exposed to several influences that may place them at increased risk for accelerated cognitive and brain aging, including: treatment with medications now known to adversely affect cholesterol, folate and glucose metabolism; increased rates of vascular disease risk factors; altered lifestyles that include decreased social interaction and physical inactivity; and elevated inflammatory markers.

The cognitive status of persons who have lived with epilepsy for a long time is unclear, says Bruce P. Hermann, lead author of the study. Because persons with epilepsy carry other risk factors for abnormal cognitive and brain aging, there should be great concern regarding the lack of knowledge about their cognitive and brain status in older years.

Previous research has identified numerous risk factors for abnormal cognitive aging and dementia in the general population, including vascular, inflammatory and lifestyle factors. Many of these factors are overrepresented in epilepsy, but not examined in relationship to cognitive and brain aging in epilepsy. This oversight is important given the epidemiological evidence that risk exposure and cognitive abnormalities in midlife represent critical predictors of eventual abnormal cognitive and brain aging.

If these factors exert comparable effects in people with chronic epilepsy, the management of epilepsy must be expanded to aggressively address critical risk factors in order to protect and promote cognitive and brain health, says Hermann.


'/>"/>

Contact: Sean Wagner
swagner@bos.blackwellpublishing.com
781-388-8550
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Study shows pine bark naturally reduces osteoarthritis
2. Study Shows Pine Bark Naturally Reduces Osteoarthritis
3. Study suggests too much screen time and not enough physical activity may lead to childhood obesity
4. St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia
5. UAB study shows investigational drug may treat biliary cancers
6. Study shows that high-dose, high-frequency interferon produces no additional benefit
7. Study finds media coverage of breast cancer focuses too little on prevention
8. USC study finds evidence of gender-related differences in development of colon cancer
9. New study in JCSM finds that obesity can predict upper airway obstruction amongst children
10. Study shows increase of hip and knee replacements in the US
11. Study shows decline in work disability due to rheumatoid arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... ... 2017 , ... Girl Up Campaign Director, Melissa Kilby, released ... support of providing girls access to education in refugee settings. In May, Congressman Steve ... Access to Education in Vulnerable Settings Act.” Yesterday, companion legislation was introduced in ...
(Date:7/20/2017)... , ... July 20, 2017 , ... ... products that further expand its existing adherence automation lines. The ATP® Mini and ... the advanced technology of TCG’s standard products, but at a size and price ...
(Date:7/20/2017)... ... 20, 2017 , ... With nearly half of all Americans ... company VisitorsCoverage Inc. has launched TMQuotes, a new cloud-based solution platform which gives ... under their own brand. The online marketplace bridges the technological gap in the ...
(Date:7/20/2017)... Henderson, Tennessee (PRWEB) , ... July 19, 2017 ... ... successful second year with a larger audience and increased funds raised to support ... two evening performances of “Disney Aladdin Kids” in Freed-Hardeman University’s Loyd Auditorium. ...
(Date:7/20/2017)... ... July 19, 2017 , ... Med Tech Solutions (MTS), a ... Health IT business unit of Constellation Inc., a move that will help the company ... operations in St. Louis, the acquisition is expected to help MTS expand ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... -- Bayer has awarded grants totaling more than $2 million to ... Bayer Hemophilia Awards Program (BHAP). Four U.S. clinicians and researchers ... and Uniformed Services University of the Health Sciences in ... were announced last night during a reception at the International ... Berlin, Germany . ...
(Date:7/11/2017)...  Sysmex America, Inc., a leading provider of ... well as middleware information systems technology, today announced ... assurance easier and more risk free than manual ... the innovation that it delivers to the laboratory. ... processes to a new level with automated, continuous ...
(Date:7/11/2017)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) ( ... development of oral drug delivery systems, announced today that ... to schedule an End-of-Phase II meeting with Oramed for ... insulin capsule ORMD-0801 in the treatment of type 2 ... endpoints by indicating a statistically significant lowering of glucose ...
Breaking Medicine Technology: