Navigation Links
Study examines role of seasonal prescribing changes in antibiotic resistance
Date:7/1/2012

[EMBARGOED FOR JULY 2, 2012] A new study published in Clinical Infectious Diseases and available online shows how seasonal changes in outpatient antibiotic use retail sales of antibiotics typically get a boost during the winter can significantly alter seasonal patterns of drug resistance. The findings suggest that hospital campaigns to reduce inappropriate antibiotic use should be coordinated with efforts in the broader community if they are to be most effective.

In the study, Dr. Ramanan Laxminarayan, director of the Center for Disease Dynamics, Economics and Policy in Washington, D.C., and research scholar at Princeton University, and Eili Klein and Lova Sun at Princeton University show a link between changing rates of antibiotic consumption and resistance. They also suggest that restrictions imposed by hospitals may be undermined if usage at the community level is not addressed. "Considering that approximately 260 million antibiotic prescriptions are filled each year," they noted, "individual hospitals' efforts to restrict antibiotic usage are unlikely to have a large effect on certain pathogens unless complemented by and coordinated with campaigns at the community level."

Dr. Laxminarayan and his colleagues demonstrate that highly seasonal temporal relationships exist between some combinations of prescriptions among five classes of antibiotics (representing almost three-quarters of yearly antibiotic prescriptions) and resistance levels of two bacteria, Escherichia coli and methicillin-resistant Staphylococcus aureus (MRSA). Specifically, resistant E. coli and MRSA were significantly correlated with lagged antibiotic prescriptions for drugs that were highly prescribed, but uncorrelated with antibiotics that were not used as often.

To analyze prescribing patterns, the researchers relied on data collected from U.S. retail pharmacies from 1999 to 2007. Information about resistance came from a repository of test results collected from more than 300 laboratories spread throughout the country. In nearly all cases analyzed, a one-month lag was found between high antibiotic prescription levels and the prevalence of resistant E. coli and S. aureus.

Because the sheer quantity of antibiotic consumption is still the main driver of resistance, Dr. Laxminarayan said, "decreasing inappropriate use through flu vaccinations and better education of both patients and physicians on when to use antibiotics will have an immediate impact." The United States still uses more antibiotics per capita than most comparable countries, and "there is room to lower prescribing without compromising on outcomes." The researchers plan future studies to examine other combinations of antibiotics and resistant bacteria, and to specify subpopulations of the U.S.


'/>"/>

Contact: Laurel White
lwhite@pcipr.com
312-558-1770
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Study answers Medicare concerns about paying for CT colonography
2. Toddlers Are Happier to Give Than Receive: Study
3. New study finds low rates of biopsy contribute to celiac disease underdiagnosis in US
4. Hot Flashes Dont Signal Poor Heart Health for Most Women: Study
5. Study finds new gene mutations that lead to enlarged brain size, cancer, autism, epilepsy
6. Gay or Straight, Parents Too Tired for Sex, Study Suggests
7. Minorities Less Likely to Use Hospice Care: Study
8. Residents as Good as Fully Trained Docs if Properly Supervised: Study
9. Study calls for drug trial patients to receive more information about effects of placebos
10. Wake Forest Baptist study suggests Tasers dont cause cardiac complications
11. Study finds genes associated with hippocampal atrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... ... August 16, 2017 , ... Any Lab Test Now® ... ranked #4429 on the newly released, 36th annual Inc. 5000 , the most ... at the most successful companies within the American economy’s most dynamic segment — its ...
(Date:8/16/2017)... ... August 16, 2017 , ... In 1987, ... celebrate 30 years in business this year, and they’re marking the milestone by ... to serve their patients. , It stands to reason that, given the ...
(Date:8/16/2017)... ... August 16, 2017 , ... QualDerm Partners ... novo development, today announced Cumberland Skin Surgery and Dermatology has joined ... with offices in both Hermitage and Lebanon, Tennessee, provides comprehensive general dermatology and ...
(Date:8/16/2017)... ... ... Maury Regional Health has announced a large-scale adoption of AccuVein vein visualization ... Regional Medical Center is making vein visualization part of their standard of care. , ... importantly, helps our staff members locate a vein that will provide good access to ...
(Date:8/16/2017)... ... August 16, 2017 , ... Paul Vitenas, MD, FACS , is honored ... The annual list identifies the nation’s top physicians, in a variety of specialties. This ... the top of Castle Connolly’s coveted ranking. , Castle Connolly is the nation’s trusted ...
Breaking Medicine News(10 mins):
(Date:7/31/2017)... , July 31, 2017 7D Surgical, developer ... Medical has purchased the 7D Surgical System to support its ... Washington D.C. and Virginia.  7D Surgical has ... for many of the premier medical facilities within those markets. ... ...
(Date:7/27/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) today reported ... The Company reported second quarter net sales of $1.954 ... period, and an increase of 2.1% on a constant ... from the LDR Holding Corporation acquisition, second quarter 2017 ... or 0.3% on a constant currency basis. ...
(Date:7/26/2017)... , July 27, 2017  Radium Medical Aesthetics, a leading medical ... to delay aging by effectively addressing several skin conditions from the ... to become rougher and more fragile. The skin becomes more transparent ... exposure to the harmful UV rays from the sun contributes to ... ...
Breaking Medicine Technology: