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Study examines repeat colonoscopy in patients with polyps referred for surgery without biopsy-proven cancer
Date:1/28/2014

DOWNERS GROVE, Ill. January 28, 2014 A new study reports that in the absence of biopsy-proven invasive cancer, a second colonoscopy done at an expert center may be appropriate to reevaluate patients referred for surgical resection. In the study, 71 percent of the lesions referred for surgery were noncancerous polyps (growths in the colon) and were treatable endoscopically. In 26 percent of cases, previous removal was attempted by the referring physician but was unsuccessful. Endoscopic treatment was performed as an outpatient procedure without serious adverse events, and hospital admission for overnight observation was necessary in only six percent of patients. The study appears in the January issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).

Endoscopic resection (removal) of colorectal precancerous polyps is an integral part of colorectal cancer screening and prevention programs. Limitations of endoscopic polyp resection include adverse events such as bleeding and perforation, significant local recurrence rates, and technical inability to resect some lesions. Large flat and sessile lesions can be particularly difficult to resect endoscopically; these lesions are often treated surgically. However, surgical resection entails significant morbidity and is associated with a low but significant risk of serious adverse events even when performed at expert centers. Recent studies have demonstrated that endoscopic mucosal resection (EMR) of large sessile and flat lesions is technically feasible and can be performed with a low risk of adverse outcomes by gastroenterologists specifically trained in this technique.

EMR is a technique in which a needle is passed through the endoscope and a liquid solution is injected under the area of interest, in effect "lifting" the abnormal tissue and separating it from the deeper intestinal layers. The abnorma
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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