Navigation Links
Study examines how brain 'reboots' itself to consciousness after anesthesia
Date:6/18/2014

One of the great mysteries of anesthesia is how patients can be temporarily rendered completely unresponsive during surgery and then wake up again, with their memories and skills intact.

A new study by Dr. Andrew Hudson, an assistant professor in anesthesiology at the David Geffen School of Medicine at UCLA, and colleagues provides important clues about the processes used by structurally normal brains to navigate from unconsciousness back to consciousness. Their findings are currently available in the early online edition of the Proceedings of the National Academy of Sciences.

Previous research has shown that the anesthetized brain is not "silent" under surgical levels of anesthesia but experiences certain patterns of activity, and it spontaneously changes its activity patterns over time, Hudson said.

For the current study, the research team recorded the electrical activity from several brain areas associated with arousal and consciousness in a rodent model that had been given the inhaled anesthetic isoflurane. They then slowly decreased the amount of anesthesia, as is done with patients in the operating room, monitoring how the electrical activity in the brain changed and looking for common activity patterns across all the study subjects.

The researchers found that the brain activity occurred in discrete clumps, or clusters, and that the brain did not jump between all of the clusters uniformly.

A small number of activity patterns consistently occurred in the anesthetized rodents, Hudson noted. The patterns depended on how much anesthesia the subject was receiving, and the brain would jump spontaneously from one activity pattern to another. A few activity patterns served as "hubs" on the way back to consciousness, connecting activity patterns consistent with deeper anesthesia to those observed under lighter anesthesia.

"Recovery from anesthesia is not simply the result of the anesthetic 'wearing
'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-794-2262
University of California - Los Angeles Health Sciences
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study examines how brain 'reboots' itself to consciousness after anesthesia
(Date:9/17/2014)... announced today that will analyze how changes in ... contribute to healthy aging. , Conducted by ... a $10 million unrestricted gift from the Amway ... identify lifestyle and environmental factors that may help ... age. WELL will be designed, conducted, and analyzed ...
(Date:9/17/2014)... latest blog post, Best Drug Rehabilitation , which offers ... a stay in rehab can make a big difference in ... member of the therapeutic care team that is making a ... and around the world: dogs. , “Studies show ... and stress levels in recovering addicts,” commented Best Drug Rehabilitation’s ...
(Date:9/17/2014)... gene manipulation these sound like the ideas ... they are components of an exciting new approach ... animal models of metastatic prostate cancer, scientists at ... of Molecular Medicine and Johns Hopkins Medical Institutions ... approach that could revolutionize doctors, ability to see ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 In Pretrial ... that “bi-weekly telephonic discovery conferences would be beneficial in ... conferences through mid-December. “At the end of December,” the ... the need for additional conferences. , “The plain ... that there is still much to be discussed as ...
(Date:9/17/2014)... Dennis Thompson HealthDay Reporter ... Exposure in the womb to household chemicals known as ... asthma, Columbia University researchers reported in a new study. ... of developing asthma between age 5 and 11 if ... of two phthalates (pronounced thal-ates), the researchers found. The ...
Breaking Medicine News(10 mins):Health News:First-ever research study examines impacts of diet and lifestyle on healthy aging 2Health News:Latest Best Drug Rehabilitation Blog Post Highlights How Dogs are Helping Addicts Recover 2Health News:New non-invasive technique could revolutionize the imaging of metastatic cancer 2Health News:New non-invasive technique could revolutionize the imaging of metastatic cancer 3Health News:Transvaginal Mesh Lawsuit News: New Order in C.R. Bard MDL Sets Schedule of Conferences for September to December, the Rottenstein Law Group LLP Reports 2Health News:Prenatal Exposure to Chemicals in Plastics Linked to Asthma Risk in Kids 2Health News:Prenatal Exposure to Chemicals in Plastics Linked to Asthma Risk in Kids 3Health News:Prenatal Exposure to Chemicals in Plastics Linked to Asthma Risk in Kids 4
... breast density and its implication on the risks of breast ... has brought to the fore, the key challenges involved in ... revealed that, those with dense breasts were five times more ... with fatty tissue in the breasts. , ,Dense breasts ...
... Fat tissue around the abdomen is an abominable sight ... worse things to come. // ,Rothwell and colleague ... warn that fat around the abdomen is enemy to ... fat cells has an adverse effect on the heart. ...
... published in the Journal of Vertebral Subluxation Research ... benefits //to children suffering from learning disabilities and ... Swiss chiropractor Yannick Pauli, DC, president of the ... care of children suffering from learning and behavioral ...
... patients who were affected by parasitic infections had a ... Sclerosis is an auto immune disease which harms the ... ,Jorge Correale and Mauricio Farez of the Raul Carrea ... information, in the Annals of Neurology. A study was ...
... has entered the fray of painkillers, especially the likes of ... soreness after a heavy work out or exercise. A new ... of coffee, consumed before a work out, may ease muscle ... Patrick O'Connor, of the department of kinesiology at the University ...
... to human community by killing around 50 million people across ... the affected bodies exhibited a strange type of reaction //wherein ... to the person affected. ,American researchers reconstructed this ... lungs of the monkeys were damaged within a week. A ...
Cached Medicine News:Health News:Chiropractic Care Helps Children With Learning Disorders and Dyslexia 2Health News:Chiropractic Care Helps Children With Learning Disorders and Dyslexia 3Health News:Work-outs, Not So Much of a ‘pain’ With Caffei 2
(Date:9/17/2014)... Minn. , Sept. 17, 2014 ACIST ... global market leader of advanced imaging modalities for cardiology, ... System in two live cases at the Transcatheter Cardiovascular ... The cases were presented from Medstar Washington Hospital Center ... Hospital/Columbia University Medical Center ( New York, NY ...
(Date:9/17/2014)... , Sept. 17, 2014   OTEMR, Inc. , ... Complete EHR certification, which designates that the software is ... 1 and Stage 2 Meaningful Use measures required to ... Act (ARRA).  ONETOUCH EMR 2.0 was certified on July ... of the National Coordinator-Authorized Certification Body (ONC-ACB) and is ...
(Date:9/17/2014)... , Sept. 17, 2014  Bayer HealthCare will ... Hemophilia Foundation,s 66 th Annual Meeting, which takes ... D.C.  The data, which will be shared through poster ... and patient care. Data will be presented in a ... into treatment modalities in hemophilia A patients, Bayer is ...
Breaking Medicine Technology:ACIST Launches HDi High-Definition IVUS 2ACIST Launches HDi High-Definition IVUS 3OTEMR, Inc.'s ONETOUCH EMR Achieves ONC HIT 2014 Edition COMPLETE EHR Certification from ICSA Labs 2OTEMR, Inc.'s ONETOUCH EMR Achieves ONC HIT 2014 Edition COMPLETE EHR Certification from ICSA Labs 3Bayer to Present Data on Hemophilia Research at NHF in Washington, D.C. 2Bayer to Present Data on Hemophilia Research at NHF in Washington, D.C. 3Bayer to Present Data on Hemophilia Research at NHF in Washington, D.C. 4
Cold light source single outlet....
Cold light source triple outlet....
Cold light source single outlet....
... is a state of the ... source with an integrated intensity ... to connect optical fiber light ... itself from all others by ...
Medicine Products: