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Study examines global availability of treatment involving transplantation of blood stem cells
Date:4/27/2010

This release is available in Chinese.

An examination of the world-wide use of hematopoietic stem cell transplantation (HSCT), which involves transplantation of blood stem cells derived from the bone marrow or blood, finds that there are significant differences in transplant rates between countries and continental regions by indication and donor type, and that HSCT is most frequently used in countries with higher gross national incomes and governmental health care expenditures, according to a study in the April 28 issue of JAMA.

"HSCT has become the standard of care for many patients with defined congenital or acquired disorders of the hematopoietic system [pertaining to the formation of blood cells] or with chemosensitive, radiosensitive, or immunosensitive malignancies. Over the last 2 decades, HSCT has seen rapid expansion in use and a constant evolution in its technology," the authors write. "It requires significant infrastructure and a network of specialists from all fields of medicine. Hence, information on indications, use of specific technologies, and trends in the application of HSCT is essential for correct patient counseling and for health care agencies to prepare the necessary infrastructure and to avoid planning errors." Little is known about HSCT use and the factors associated with it on a global level.

Alois Gratwohl, M.D., of University Hospital Basel, Switzerland, and colleagues conducted a study to assess differences in the application of HSCT on a global level and to examine associations of various factors with transplant rates. The study included patients receiving allogeneic (genetically different) and autologous (derived from the same individual) HSCTs for 2006, collected by 1,327 centers in 71 participating countries of the Worldwide Network for Blood and Marrow Transplantation. The regional areas used in
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Contact: Alois Gratwohl, M.D.
hematology@uhbs.ch
JAMA and Archives Journals
Source:Eurekalert

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