Navigation Links
Study examines association between caffeine consumption and breast cancer risk
Date:10/13/2008

Caffeine consumption does not appear to be associated with overall breast cancer risk, according to a report in the October 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. However, there is a possibility of increased risk for women with benign breast disease or for tumors that are hormone-receptor negative or larger than 2 centimeters.

Caffeine is probably the most commonly consumed drug worldwide, present in coffee, tea, chocolate and some medications, according to background information in the article. It was hypothesized that caffeine may increase the risk of breast cancer after a study showed that women with non-cancerous breast disease experienced relief from their symptoms after removing caffeine from their diet.

Ken Ishitani, M.D., Ph.D., of Brigham and Women's Hospital and Harvard Medical School, Boston, and Tokyo Women's Medical University, Japan, and colleagues studied 38,432 women 45 years or older who provided dietary information in 1992-1995. Over an average of 10 years of follow-up, 1,188 of the women developed invasive breast cancer.

"Consumption of caffeine and caffeinated beverages and foods was not statistically significantly associated with overall risk of breast cancer," the authors write. Among women with benign breast disease, a non-significant positive association with breast cancer risk was observed for those in the highest quintile (one-fifth) of caffeine consumption and a significant association was observed for those in the highest category of coffee consumption (four cups or more daily).

Consuming caffeine was also associated with a 68 percent increased risk of estrogen receptornegative and progesterone receptornegative breast cancer, or tumors to which the hormones estrogen and progesterone do not bind, and a 79 percent increased risk for breast tumors larger than 2 centimeters.

"The mechanisms by which caffeine may affect breast carcinogenesis [cancer development] are complex and remain unclear," the authors write. "In the present investigation, caffeine consumption was associated with increased risk of breast cancers negative for both estrogen receptors and progesterone receptors or larger than 2 centimeters, which have less favorable prognoses. These findings indicate that caffeine consumption may affect breast cancer progression, and such an effect may be independent of the estrogen pathway." Further study is required to better understand caffeine's role, they note.


'/>"/>

Contact: Lori J. Shanks
617-534-1604
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... , ... Lori R. Somekh, founder of the Law Office of Somekh ... law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up ... network with elder law attorneys nationwide,” said Somekh. , ElderCounsel was ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... Abilene, Texas (PRWEB) , ... October 13, 2017 , ... ... publication this week that explains one of the most popular and least understood books ... seems like cryptic and puzzling descriptions that have baffled scholars for centuries. Many have ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Halo Labs announces the European launch of their new ... at MIBio 2017 in Cambridge, U.K on ... in biopharmaceutical samples with unprecedented speed and sensitivity while using far ... Membrane Imaging. ... particle analysis system ...
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, ... 2017 earnings conference call and webcast on Friday, November ... a.m. (EDT) and ending at approximately 8:30 a.m. (CDT) ... discussing the company,s 2017 financial performance and guidance for ... opportunities, initiatives to enhance operational performance, and long-range financial ...
(Date:9/27/2017)... 2017  Commended for their devotion to personalized service, SMP ... number one in the South Florida Business Journal,s 50 Fastest-Growing ... yearly list, the national specialty pharmacy has found its niche.  ... will soon be honored by SFBJ as the 2017 Power ... Set to receive his award in October, Bardisa said of ...
Breaking Medicine Technology: