Navigation Links
Study examines adverse effects among different radiation therapies for prostate cancer
Date:4/17/2012

used Surveillance, Epidemiology, and End Results-Medicare-linked data from 2000 through 2009 for patients with localized prostate cancer. The primary outcomes measured were rates of gastrointestinal adverse effects (such as rectal bleeding or diarrhea) and urinary adverse effects, erectile dysfunction, hip fractures, and receipt of additional cancer therapy as an indicator for disease recurrence.

The use of IMRT vs. conformal radiation therapy increased from 0.15 percent in 2000 to 95.9 percent in 2008. In the propensity-score adjusted analysis (n = 12,976), the researchers found that men treated with IMRT were less likely to receive a diagnosis of gastrointestinal adverse effects and hip fracture but more likely to receive a diagnosis of erectile dysfunction. Also, IMRT patients were nearly 20 percent less likely to receive additional cancer therapy.

In a propensity score-matched comparison between IMRT and proton therapy (n = 1,368), IMRT patients had a 34 percent lower risk of gastrointestinal adverse effects. There were no significant differences in rates of other adverse effects or additional therapies between IMRT and proton therapy.

"Proton therapy is a high-profile, high-cost prostate cancer treatment. Since 2007, multiple proton facilities have been built, and direct-to-consumer advertising is likely to lead to a substantial increase in use," the authors write. "Overall, our results do not clearly demonstrate a clinical benefit to support the recent increase in proton therapy use for prostate cancer."

The researchers add that the findings that patients receiving IMRT were less likely than those receiving conformal radiation therapy to undergo additional cancer treatments is consistent with the use of IMRT to deliver dose-escalated treatment, resulting in improved cancer control, as demonstrated by randomized trials. "Taken together, these results suggest that IMRT facilitated radiation dose escalation without compromisin
'/>"/>

Contact: Dianne Shaw
dgs@med.unc.edu
919-923-6012
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014 A new study published ... increase in disability associated with speech problems from 2001-02 ... than 15% increase in disability associated with hearing problems. ... rising numbers of children who are experiencing communication disorders, ... , On a broader level, the new study, ...
(Date:8/21/2014)... care physicians in rural communities do not routinely ... to Penn State medical and public health researchers. ... have limited resources if they seek help., "Rural ... women," said Jennifer S. McCall-Hosenfeld, a primary care ... health sciences, Penn State College of Medicine. "However, ...
(Date:8/21/2014)... August 21, 2014 Xarelto lawsuit ( ... patients to suffer uncontrollable internal bleeding and other serious ... LLP reports. According to court documents, a wrongful death ... Court, Easter District of New York by the family ... bleeding event that was allegedly caused by Xarelto. Among ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 The ... manufactured by Boston Scientific has begun in Massachusetts ... bellwether trial. The Rottenstein Law Group LLP, a ... with claims of harm stemming from the implantation ... claim for compensation for injuries suffered at ...
(Date:8/21/2014)... Annapolis, MD (PRWEB) August 21, 2014 ... real estate organizations to obtain industry-focused data, is ... out healthcare real estate data on the Southeast, ... RevistaMed.com/PropertySearch – the first widely available, ... , The total number of searchable properties, including ...
Breaking Medicine News(10 mins):Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 3Health News:Primary care physicians can be critical resource for abused women in rural areas 2Health News:Xarelto Lawsuits Mount With New Filing in New York Federal Court, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuits Mount With New Filing in New York Federal Court, Bernstein Liebhard LLP Reports 3Health News:Xarelto Lawsuits Mount With New Filing in New York Federal Court, Bernstein Liebhard LLP Reports 4Health News:Transvaginal Mesh Lawsuit News: Second Boston Scientific Mesh Bellwether Trial Begins, The Rottenstein Law Group LLP Reports 2Health News:Revista Medical Property Data Now Available for the Mid-Atlantic, Southeast and Midwest Regions 2Health News:Revista Medical Property Data Now Available for the Mid-Atlantic, Southeast and Midwest Regions 3Health News:Revista Medical Property Data Now Available for the Mid-Atlantic, Southeast and Midwest Regions 4Health News:Revista Medical Property Data Now Available for the Mid-Atlantic, Southeast and Midwest Regions 5
... , TUESDAY, Feb. 1 (HealthDay News) -- Many black ... interaction stressful and don,t feel physicians give them enough useful ... suggests. The findings stem from a series of focus ... result: doctors are viewed as coming up short when it ...
... cancer cells dodge the immune system and promote tumor growth, ... disease. While comparable mechanisms to avoid the immune system have ... study tested human breast tumor cells, putting researchers closer to ... The study, published in the journal Cancer Research , ...
... targeted breast biopsies for patients with early breast cancer, ... from undergoing a second breast cancer surgery, a new ... undergo a sentinel lymph node biopsy to determine if ... author of the study. Ultrasound, on its own, ...
... , TUESDAY, Feb. 1 (HealthDay News) -- Finally some good ... with their parents behave better, have stronger mental health and ... study. Researchers at Brigham Young University,s School of Family ... to 16. They found that the most popular video games ...
... screening for breast cancer delivers consistent rates of cancer detection ... study published online and in the April print edition of ... than mammography at identifying suspicious areas of the breast, it ... lesions, which can result in additional testing and false-positive results ...
... published a new international multidisciplinary classification of lung adenocarcinoma, ... The new classification is published in the February ... the official publication of the International Association for the ... rapid advances in lung adenocarcinoma affecting clinical, radiologic, pathologic, ...
Cached Medicine News:Health News:Study Examines Reasons Some Black Men Avoid Doctors 2Health News:Breast cancer cells outsmart the immune system and thrive 2Health News:Breast cancer cells outsmart the immune system and thrive 3Health News:Microbubble ultrasound and breast biopsies 2Health News:Girls Win When They Play Video Games With Parents: Study 2Health News:Repeat MRI screening for breast cancer results in fewer false positives 2Health News:Lung societies unveil new international classification of lung adenocarcinoma 2
(Date:8/21/2014)...   Auxilium Pharmaceuticals, Inc. (NASDAQ: ... announced positive results from a randomized, double-blind Phase ... for the treatment of edematous fibrosclerotic panniculopathy (EFP), ... trial, all three doses of CCH (low (0.06mg), ... in the appearance of cellulite as measured by ...
(Date:8/20/2014)... Aug. 20, 2014 The National Association ... latest results achieved by the real-time, pseudoephedrine (PSE) ... National Precursor Log Exchange (NPLEx), automatically blocks unlawful ... down meth offenders and make arrests. Data released ... Kansas blocked the sale of more ...
(Date:8/20/2014)... NEW YORK , Aug. 20, ... a new market research report is ... The Market for Hospital-Acquired Infection Control ... http://www.reportlinker.com/p01618925/The-Market-for-Hospital-Acquired-Infection-Control-Sterilization-Disinfection-Testing-and-Treatment.html ... and healthcare-associated infections (HAIs), demand has ...
Breaking Medicine Technology:Auxilium Pharmaceuticals, Inc. Announces Positive Data From Phase 2a Study Of CCH In Patients With Cellulite 2Auxilium Pharmaceuticals, Inc. Announces Positive Data From Phase 2a Study Of CCH In Patients With Cellulite 3Auxilium Pharmaceuticals, Inc. Announces Positive Data From Phase 2a Study Of CCH In Patients With Cellulite 4Auxilium Pharmaceuticals, Inc. Announces Positive Data From Phase 2a Study Of CCH In Patients With Cellulite 5Auxilium Pharmaceuticals, Inc. Announces Positive Data From Phase 2a Study Of CCH In Patients With Cellulite 6Auxilium Pharmaceuticals, Inc. Announces Positive Data From Phase 2a Study Of CCH In Patients With Cellulite 7Kansas's Stop-Sale System Achieves Significant Results In Battle Against Meth 2The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 2The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 3The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 4The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 5The Market for Hospital-Acquired Infection Control (Sterilization, Disinfection, Testing and Treatment) 6
... 2007 /PRNewswire-FirstCall/ --,Pharmacyclics, Inc. announced today multiple ... gadolinium),Injection, including an oral presentation of Phase ... Gadolinium And Radiation,Therapy) trial data. The presentations ... the 2007 American Society of Clinical Oncology,Annual ...
... Potential Benefit of Unique OROS(R),Formulation, SAN DIEGO, ... abuse,remains an ongoing concern for parents and ... Hyperactivity Disorder,(ADHD). Data presented on Tuesday at ... Association highlighted findings that,long-acting OROS(R) methylphenidate had ...
Cached Medicine Technology:Pharmacyclics Announces Presentations and Published Abstracts on,Xcytrin at The 2007 American Society of Clinical Oncology Annual,Meeting 2New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 2New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 3New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 4New Data Suggests Less Abuse-Related Effects For OROS,Methylphenidate 5
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: