Navigation Links
Study details cost-effectiveness of rheumatoid arthritis treatments for Medicare recipients
Date:4/14/2008

Bank for Rheumatic Diseases. Starting with baseline characteristicsincluding disease duration and score on the disability index of the Health Assessment Questionnaire (HAQ DI)of actual patients treated with each of the targeted biologic drugs, the model simulated a representative sample of 10,000 RA patients. Using these simulated patients, the model assessed the effectiveness of the 4 options, based on the level of American College of Rheumatology (ACR) response and the HAQ DI score for each patient. Beginning after a 6-month course of biology therapy, scores were taken every 6 months until withdrawal, due, for example, to loss of effectiveness or adverse event, and then, assuming a return to DMARD-based therapy, every 6 months throughout the remainder of the patients life. The score for each patient was translated into quality-adjusted life years (QALYs), a measure of benefit that can be used across a wide range of diseases and treatments. The model then calculated the costs incurred for each Medicare patient, including the costs of the biologic drugs, physician visits, other medications, hospitalizations, radiographs, and laboratory work. Finally, the researchers compared the costs and QALYs generated by each of the 4 biologic agents.

In all simulations, anakinra was found to generate less QALYs than the TNF inhibitors. Excluding anakinra to compare the costs of the 3 almost equally effective drug strategies, researchers used a range of $0 to $200,000 as the values a decision-maker may be willing to pay per additional QALY gained. Infliximab was the optimal strategy in only a handful of the simulations. If society were willing to pay as much as $50,000 per QALY, the probability that infliximab would be cost-effective is less than 1 percent.

Our analysis suggests that the use of etanercept or adalimumab in place of infliximab as a first-line biologic agent is likely to be considered cost effective, concludes the studys lead aut
'/>"/>

Contact: Sean Wagner
swagner@bos.blackwellpublishing.com
781-388-8550
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Study sheds light on deadly lung disease
2. NovoCure presents results from breast cancer pilot study
3. Mayo-led study finds smoking related to subset of colorectal cancers
4. National hospice study reveals gaps in service
5. Study Points to New Treatments for Polycystic Kidney Disease
6. MRI better than MDCT in detecting endoleaks, study says
7. Personality study shows risk of first depression episode late in life
8. 3T MRI plays significant role in detecting prostate cancer, study says
9. Study shows doctors offices can help stem abuse of Oxycontin, other narcotic painkillers
10. Quintiles Ranks First in Pan-European Clinical Investigator Study
11. Study Showed Minimally Invasive Surgery Reduced Risk of Hospital-Acquired Infections Compared to Open Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... Holbrook, CP LP, has joined Fourroux Prosthetics, headquartered in ... experience in the prosthetics field. He graduated from ... Science degree with a major in biology and a ... in prosthetics at Northwestern University in Chicago, Illinois. , ... Fourroux,” says Keith Watson, owner of Fourroux. “His ...
(Date:8/27/2014)... For nearly two decades, audiences around the ... singers Deva Premal & Miten with their rapturous Nepali ... latest album in May, their 2014 MANTRAS FOR LIFE ... the globe, including Russia, Ukraine, Israel, Australia, the U.S., ... a new album and a new five-piece band, the ...
(Date:8/27/2014)... (HealthDay News) -- In a new study done from ... your blood pressure steadily increases if you ascend to ... widely used to treat high blood pressure was ineffective ... findings, reported online Aug. 27 in the European ... but those at sea level who have sleep apnea, ...
(Date:8/27/2014)... (HealthDay News) -- A new genetic discovery about Crohn,s ... bowel disorder, researchers report. The scientists pinpointed ... their genes work, and said these changes can be ... possibility of a simple diagnostic test for Crohn,s, the ... and suggest possible gene targets for new treatments, said ...
(Date:8/27/2014)... Princeton, NJ (PRWEB) August 27, 2014 ... revenue enhancement and protection services for hospitals, is pleased ... 2014 Inc. 5000 List of America’s Fastest-Growing Companies. The ... segment of the economy—America’s independent entrepreneurs. , "It's ... are honored to be included in this year's Inc. ...
Breaking Medicine News(10 mins):Health News:Deva Premal & Miten's Mantras For Life Tour Announced 2Health News:Deva Premal & Miten's Mantras For Life Tour Announced 3Health News:Everest Study Finds High Altitude Affects Blood Pressure 2Health News:Scientists Spot Genetic Clues to Crohn's Disease 2Health News:BESLER Consulting Among America’s Fastest Growing Private Companies 2
... Blue Cross Blue Shield of Michigan announced today that Kevin ... current vice president for products and marketing, will succeed Jeanne ... when Carlson retires at the end of February 2010. , ... and CEO of BCBSM, parent company of Blue Care Network. ...
... - Proposed 30-Year Lease Agreement Will Help Stevens Hospital Expand, ... Wash., Dec. 17 The Board of Commissioners for Public ... for Swedish to lease and assume management of Stevens Hospital ... agreements. The public is invited to a hearing in mid-January ...
... from physician, study finds , THURSDAY, Dec. 17 (HealthDay News) ... parents to place infants on their backs to go to ... SIDS, researchers have found. , Since the U.S. government launched ... infants placed on their backs at sleep time has increased ...
... checkout counters of clothing stores, gas stations -- and adding ... News) -- If you,re hungry while shopping for a new ... sell sweet or salty snacks, a new report finds. , ... far beyond grocery stores to hit most segments of the ...
... ... Fisher Theatre on Dec. 17 for the Detroit-area,premiere of the award-winning musical “Jersey Boys,” Beaumont ... , ... When the cast takes the stage at the Fisher Theatre on Dec. 17 for the ...
... might be more likely to try alcohol, illegal drugs ... believe that smoking cigarettes is riskier than using illicit ... , That perception may increase the likelihood that they,ll ... said. , "We are on the right track with ...
Cached Medicine News:Health News:Stevens Hospital to Affiliate with Swedish 2Health News:Stevens Hospital to Affiliate with Swedish 3Health News:Stevens Hospital to Affiliate with Swedish 4Health News:Doctor's Orders Influence Baby's Sleep Position 2Health News:Wide Array of Stores Now Sell High-Calorie Snacks 2Health News:Jersey Boys' Premiere Benefits Cancer Patients While Launching Beaumont Hospitals Fundraising Campaign 2Health News:Jersey Boys' Premiere Benefits Cancer Patients While Launching Beaumont Hospitals Fundraising Campaign 3Health News:Teens Think Smoking More Dangerous Than Drinking, Drugs 2
(Date:8/27/2014)... ANGELES , Aug. 27, 2014   Los ... now offers AcceleDent® Aura to patients who want to ... orthodontic care available at the OrthoSpaceship, all patients have ... better-looking teeth. This system can be used by most ... their rate of progress by using the AcceleDent® Aura ...
(Date:8/27/2014)... -- Decision Resources Group finds that the intense physician ... health system and hospital sector in recent years ... Le Bonheur Healthcare and Baptist Memorial Health Care pulling ... In addition, a national contract recently signed between Tenet ... in the Memphis market, sets ...
(Date:8/27/2014)... August 27, 2014 According ... Products (Dental Radiology, CAD/CAM, Dental Chairs, Dental Lasers), Current Trends, ... MarketsandMarkets, the global Dental Equipment Market is expected to ... in 2014, growing at a CAGR of 5.7% ... market data tables and 61 figures spread through ...
Breaking Medicine Technology:Los Angeles Orthodontist, Dr. Isaac Hakim, is Now Offering AcceleDent Aura 2Memphis-area Health Systems Turn Attention to Clinical Integration 2Dental Equipment Market Worth $7,138.9 Million by 2019 2Dental Equipment Market Worth $7,138.9 Million by 2019 3
... Ten percent of cancer patients failed to fill their initial prescriptions ... today in the Journal of Oncology Practice ( JOP ... ). The study was based on an analysis conducted by Avalere ... 2007 to 2009. This study has also been accepted for presentation ...
... The Consumer Healthcare Products Association (CHPA), representing makers ... applauds the U.S. Food and Drug Administration (FDA) ... children the right amount of medicine. Today, the ... Committee recommended enhancing the labels of all OTC ...
Cached Medicine Technology:New Study Finds That 10% of Cancer Patients Abandoned Oral Anti-Cancer Drugs 2New Study Finds That 10% of Cancer Patients Abandoned Oral Anti-Cancer Drugs 3New Study Finds That 10% of Cancer Patients Abandoned Oral Anti-Cancer Drugs 4OTC Industry Supports FDA Advisory Committee Recommendations on New Dosing Instructions 2OTC Industry Supports FDA Advisory Committee Recommendations on New Dosing Instructions 3
Inquire...
Inquire...
Protects the skin over extended wearing time from irritating discharge. Flextend skin barrier is the barrier of choice for urostomies and ileostomies with the added benefit of it being discreet in bo...
Inquire...
Medicine Products: