Navigation Links
Study confirms accuracy of transient elastography in NAFLD
Date:1/27/2010

The research team evaluated 246 patients from two ethnic groups from two hospitals in France and Hong Kong with valid LSM acquisitions and satisfactory liver biopsy specimens. Men who consumed more than 30 g of alcohol per week and women who consumed more than 20 g of alcohol per week were excluded. Patients with secondary causes of hepatic steatosis (e.g. chronic use of systemic corticosteroids), positive hepatitis B surface antigen or anti-hepatitis C virus antibody, or histologic evidence of other concomitant chronic liver diseases were also excluded. Since the aim of transient elastography was to diagnose significant fibrosis and early cirrhosis, patients with clinical and radiological evidence of cirrhosis were excluded.

Researchers found that successful measurement could be obtained in over 97% of patients with BMI below 30 kg/m2 and 75% of obese patients. LSM was not affected by hepatic steatosis, necroinflammation and obesity. Most discordance between TE and histology occurred in patients with short liver biopsy lengths and mild or no fibrosis. In addition, TE had superior performance to other non-invasive biochemical tests in diagnosing advanced fibrosis and cirrhosis.

"The adoption of transient elastography could potentially spare two-thirds of NAFLD patients from liver biopsies. Since the prevalence of NAFLD is high in many affluent countries, this approach would be cost saving," speculates Dr. de Ldinghen.

Dr. de Ldinghen also cautions that while TE has a high negative predictive value, the positive predictive value of TE and other noninvasive tests to diagnose advanced fibrosis in NAFLD patients remains modest. He states, "The main value of these tests is to exclude advanced fibrosis as screening tests. Based on our data, it is reasonable to consider liver biopsy in patients whose LSM is 7.9 kPa or above."

Leon Adams, associate professor at the University of Western Australian and author of this month's editori
'/>"/>

Contact: Dawn Peters
medicalnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... San Jose, CA (PRWEB) April 17, 2015 ... of life insurance protection without modifications can now use ... are now general life insurance policy rates that are ... . , The standard plans that are offered are ... for adults aged 18 to 79. There are now ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 Enthusiasts of gourmet ... Rapids, Saturday, April 25, 2015. The event will be held ... & Food (201 Monroe Ave NW, Grand Rapids, MI 49503) ... the West Michigan area. Patrons are encouraged to savor the ... and fun. , This year’s event will feature seven chefs, ...
(Date:4/17/2015)... April 17, 2015 At the end ... Lounge and the “Salute to the Oscars” in the ... Hilton Hotel, overlooking the impressive Los Angeles skyline. These ... by Debbie Durkin, LA’s leading producer of sustainable product ... of the world’s premier providers of eco-friendly and socially ...
(Date:4/17/2015)... New York, New York (PRWEB) April 17, 2015 ... ) that allege this class of prescription ... suffer a heart attack, stroke or other life-threatening ... litigation underway in U.S. District Court, Northern District ... issued by the U.S. Judicial Panel on Multidistrict ...
(Date:4/17/2015)... Organic Valley, the nation’s largest cooperative ... International Year of Soils by “Cycling for Sustainability” through ... employees will travel 215 miles from Auburn, California, to ... about the impact of agriculture on water and soil ... Maine, Wisconsin, Oregon, and Washington state, the cyclists have ...
Breaking Medicine News(10 mins):Health News:General Life Insurance Policy Rates Added to Quotation System at Insurance Website Online 2Health News:Children’s Leukemia Foundation of Michigan Presents 3rd Annual CRUSH Grand Rapids 2Health News:Choices Recovery Speaks with Dakota Hood of “The Hunger Games” about Addiction in Hollywood 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 3Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 4Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 2Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 3
... Amanda Gardner HealthDay Reporter , THURSDAY, May 26 ... in people whose pain is triggered by certain visual patterns, ... who have migraines accompanied by visual "aura," such as flashes ... a study appearing in the May 26 issue of the ...
... prevent organ transplantation rejection, inhibits breast cancer growth in ... in the May 26th PLoS ONE. Nancy Klauber-DeMore, ... have a rationale for performing human clinical trials to ... Since Tacrolimus is already an FDA-approved drug, the safety ...
... in the swine flu virus over the past three decades can ... pigs, a new study reports. The finding stems from an ... were transported from one region to another, the genetic material of ... the diversity of the virus, according to the study, done by ...
... residents of the Stroke Belta southern portion of the ... greater incidence of cognitive decline than other regions of ... of this population are to blame. Results of this ... and Stroke (NINDS), are published in Annals of ...
... Gordon HealthDay Reporter , WEDNESDAY, May 25 (HealthDay ... percent between 1998 and 2007, new government research shows. ... powerful germs -- Neisseria meningitidis and Streptococcus ... fewer infections among young children, the burden of the disease ...
... Precision tinted lenses have been used widely to ... increasingly used for migraine sufferers, but until now the ... published in the journal Cephalalgia , published by ... first time to suggest a neurological basis for these ...
Cached Medicine News:Health News:Special Tinted Glasses May Stymie Migraines 2Health News:Common transplant drug inhibits breast cancer growth, UNC laboratory study shows 2Health News:Tracking Swine Flu Virus in Pigs Reveals Mutations 2Health News:Cognitive decline incidence higher in Southern stroke belt 2Health News:CDC Report Shows Bacterial Meningitis Cases on the Decline 2Health News:CDC Report Shows Bacterial Meningitis Cases on the Decline 3Health News:CDC Report Shows Bacterial Meningitis Cases on the Decline 4Health News:Tinted specs offer real migraine relief, says fMRI study 2Health News:Tinted specs offer real migraine relief, says fMRI study 3
(Date:4/17/2015)... 2015 Research and Markets ( ... "Medical Device Outsourcing - Global Strategic Business ... This report analyzes the worldwide markets for Medical ... Device Categories: Class I, Class II, and Class ... report Include - Radiology, Orthopedic, Neurology, Cardiology, and ...
(Date:4/17/2015)... 17, 2015  Trovagene, Inc., (NASDAQ:  TROV) a ... clinical data presented at the 2015 European Lung ... Cancer Monitoring ℠ (PCM) platform outperformed tissue ... EGFR T790M mutations in metastatic lung cancer ... T790M Mutation in Urinary Circulating Tumor DNA from ...
(Date:4/17/2015)... Steven Rash , the CEO of Algae ... subsidiary American Seed & Oil Company, presented the Company,s ... in New York City.  Mr. Rash,s presentation featured the ... & Oil Company has recently announced the Dube ... Foods , the EpiVape , and Hempster ...
Breaking Medicine Technology:Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 2Medical Device Outsourcing (Radiology, Orthopedic, Neurology, Cardiology, and Others) Market 2015 - Global Strategic Business Report 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 4American Seed & Oil Company Benchmarks its Consumer Product Development Strategy Against Proctor & Gamble 2American Seed & Oil Company Benchmarks its Consumer Product Development Strategy Against Proctor & Gamble 3
... Ultra MD Super Pulse sealed CO2 ... versatility backed by the experience and support ... years of surgical laser experience. All settings ... finger. The Ultra MD Super Pulse surgical ...
The compact size and portability of the Epic system makes it a cost-effective solution for single or multi-office use....
A soft contact lens that lets presbyopes see clearly and comfortably at all distances , without the hassles of bifocals or reading glasses. Recommended for daily wear. Also approved for extended wear...
... display of corneal layers: endothelium, ... epithelial layers. Accurate analysis of ... keratocytes, nerve fibres, basal & ... surgery and pathology: optical pachymetry, ...
Medicine Products: