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Study compares effectiveness of 2 vs. 3 doses of HPV vaccine for girls and young women
Date:4/30/2013

study, including the JAMA Report video, embedded and downloadable video, audio files, text, documents, and related links. This content will be available at 3 p.m. CT Tuesday, April 30 at this link.

Editorial: HPV Vaccination - Too Soon for 2 Doses?

" the study by Dobson et al provides encouraging preliminary evidence that a 2-dose quadrivalent HPV vaccine series in girls may be as immunogenic as a 3-dose series in women, although the duration of protection may be less," writes Jessica A. Kahn, M.D., M.P.H., and David I. Bernstein, M.D., M.A., of the Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, in an accompanying editorial.

"If future studies establish that a 2-dose series leads to a durable immune response and effectively prevents HPV-related cancers in both women and men, the benefits would be substantial for reducing the global burden of cervical cancer and other HPV-related diseases. The potential to further reduce morbidity and mortality due to HPV-related cancers would be especially significant in less developed regions of the world, where the cost of vaccination and implementation of adolescent vaccination programs present significant barriers, but where primary prevention strategies are most urgently needed."

(JAMA. 2013;309(17):1832-1833; Available pre-embargo to the media at http://media.jamanetwork.com)

Editor's Note: Please see the article for additional information, including financial disclosures, funding and support, etc.


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Contact: Brian Lin
brian.lin@ubc.ca
604-822-2234
The JAMA Network Journals
Source:Eurekalert

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