Navigation Links
Study calls for increased research in flu transmission to prepare for pandemic flu outbreak
Date:2/18/2009

PROVIDENCE, RI Researchers at Rhode Island Hospital have completed a study to better understand the impact of infection control measures during a possible flu pandemic. Their study focused on the likelihood of the transmission of flu from individuals showing no symptoms (asymptomatic) or from individuals who are infected but have not yet exhibited symptoms. The researchers call on the scientific community to better understand the transmission of influenza in order to provide guidelines for effective pandemic flu planning. Their findings are published in the March-April 2009 edition of Public Health Reports.

The study, from Rhode Island Hospital's department of epidemiology and infection control and the division of infectious diseases, notes that public health measures for controlling outbreaks involve isolation of symptomatic individuals and the quarantine of individuals with whom they have had contact. This intervention is dependent upon early identification of symptoms, and the success of the intervention can be limited by transmission that occurs prior to symptom onset and transmission from asymptomatic infection.

Senior author Leonard Mermel, DO, ScM, medical director of the department of epidemiology and infection control at Rhode Island Hospital, along with Eleni Patrozou, MD, performed a systematic review of literature on viral shedding and disease transmission. The review included animal studies, human studies, inoculation experiments, vaccine and antiviral drug efficacy studies, and observations during outbreaks.

Mermel says, "Our findings indicate that pre-symptomatic transmission of influenza has been inferred based on the presence of the virus in the upper respiratory tract rather than from the appropriate transmission experiments. This is troubling because our review of the literature does not support significant influenza transmission based on positive nasopharyngeal cultures in the absence of symptoms."

Their findings also indicate that small-particle aerosols expelled from infected individuals may play a greater role in influenza transmission than previously recognized. The problem, however, is that it remains unclear as to how many of these droplets are generated by asymptomatic or pre-symptomatic individuals.

Mermel adds, "Asymptomatic individuals may shed influenza virus, but studies have not conclusively determined if these individuals effectively transmit influenza to others. Our review of the literature suggests that the role of asymptomatic or pre-symptomatic influenza-infected individuals in disease transmission may have been overestimated in recent articles that have served as the basis for national and international pandemic planning."

He concludes, "Based on the historical record over the last century, we must be prepared for another pandemic. Our research tells us that a better understanding of transmission dynamics is essential if we are to develop effective influenza pandemic plans."


'/>"/>

Contact: Nancy Cawley
ncawley@lifespan.org
Lifespan
Source:Eurekalert

Related medicine news :

1. Statins Pay Off on a Health-Policy Level, UCSF Study Finds
2. Major study on DiagnoCures GCC biomarker published in Jama
3. Dosing Begins in Phase 1 Clinical Study Evaluating NKTR-105 in Cancer Patients With Refractory Solid Tumors
4. Newly Published Menopause Study: Bioidentical and FDA-Approved Divigel(R) (estradiol gel) 0.1 Percent Safe and Effective Treatment for Moderate to Severe Hot Flashes Associated With Menopause
5. New Study Shares Benchmarks for Medical Science Liaisons: Gaining Access and Forging Relationships with Key Opinion Leaders
6. Study finds that using wakefulness tests to detect daytime sleepiness in drivers may be unreliable
7. Study finds behavioral link between insomnia and tension-type headaches
8. IMPACT Study Demonstrates That Longer Prophylactic Therapy With Valcyte(R) (Valganciclovir Hydrochloride Tablets) Increases Protection Against CMV - the Most Serious Viral Infection Affecting Transplant Patients
9. Sponsor Dollars Key to Flu Vaccine Study Publication
10. Tobacco Companies Targeting Teens, Study Says
11. New CDC Study Shows Tobacco Marketing Influences Kids to Smoke, Underscores Need for FDA Regulation of Tobacco Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... 2016 , ... According to an article published February 4th on ... portion of hernia repairs throughout the United States. Commenting on this article, Beverly Hills ... this trend has not only been expected, but it seems to be a natural ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... announced a new initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop the advanced skills ... recruit top students from U.S. universities who will draw from Siemens’ deep ...
(Date:2/12/2016)... Church, VA (PRWEB) , ... February 12, 2016 ... ... Store?, Feb. 29, 2016 — 1:30 p.m. – 3:00 p.m. EST, http://www.fdanews.com/fixeddosecombination ... issue in the life cycle of pharmaceutical products, garnering increased attention from all ...
(Date:2/12/2016)... ... ... Coco Libre, the maker of coconut water beverages with a purpose, is ... Coco Libre will offer musicians and celebrities the company’s signature Organic Coconut Water, a ... suite, held this year at the W Hollywood Hotel, has become a pre-show “must” ...
(Date:2/12/2016)... ... February 12, 2016 , ... Itopia, a ... the integration of Clarity Intelligence Platform (CIP) into Cielo®, a discovery, migration and ... intelligence (BI) to their small and medium business (SMB) clients. , ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... LONDON , Feb. 11, 2016 The ... current and future adoption patterns on the usage of ... include the following: - Timeframe of liquid ... types—CTCs, ctDNA, cfDNA and Evs—by organization type - Sample ... sample types: blood, saliva, stool, serum, and so on. ...
(Date:2/11/2016)... -- PRO-DEX, INC. (NasdaqCM: PDEX) today announced financial results for ... Company also filed its Quarterly Report on Form 10-Q for ... and Exchange Commission today. --> ... --> --> Net sales for the three ... to $5.4 million from $2.8 million for the three months ...
(Date:2/11/2016)... 2016  Kindred Biosciences, Inc. (NASDAQ: KIN ), ... lives of pets, today announced the submission to FDA ... Drug Application (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive ... Zimeta for the control of pyrexia (fever) in horses ... --> --> The Chemistry, Manufacturing, and ...
Breaking Medicine Technology: