Navigation Links
Study Supports Link Between Stress, Epileptic Seizures
Date:12/4/2012

By Maureen Salamon
HealthDay Reporter

TUESDAY, Dec. 4 (HealthDay News) -- Scientists have long thought that stress plays a role in epileptic seizures, and new evidence suggests that epilepsy patients who believe this is the case experience a different brain response when faced with a nerve-wracking situation.

Researchers from the University of Cincinnati performed functional MRI brain scans during a stressful math exercise on 16 epilepsy patients who pegged stress as a factor in their seizure control and seven patients who did not. While both groups performed similarly on the test, those who perceived stress to have an impact on their epilepsy showed greater brain activation than the others during intimidating parts of the test.

"One of the things we often hear is that a lot of epilepsy patients feel their seizures are affected by stress . . . but no one had really looked at their [brain response] or other elements of their physiological response," said study author Jane Allendorfer, an instructor of neurology at the University of Alabama at Birmingham. Allendorfer worked at University of Cincinnati while the study was conducted.

"We were a bit surprised to see this difference," she added, "but really excited to see it as well because this is something that hadn't been done before."

The research was scheduled to be presented Monday at the annual meeting of the American Epilepsy Society, in San Diego. Data presented at scientific conferences often has not been peer-reviewed or published and is considered preliminary.

A brain disorder producing repeated seizures, epilepsy affects more than 2 million people in the United States, according to the U.S. Centers for Disease Control and Prevention. An estimated 50 million to 65 million people are affected by the condition worldwide.

For the new study, all participants were initially given simple subtraction problems to solve and then a "stress task" during which they performed difficult subtraction. Participants were given positive feedback during the easier portion and negative feedback during the difficult section regardless of how well they were actually performing.

The brain activation observed on MRI among those who perceived stress to impact their seizures was seen in several regions, including the left temporal lobe, where their epilepsy originated. No such brain activation was noted in the comparison group.

An epilepsy expert said the study results reflect what he hears from patients.

"Everyone who treats a lot of seizure patients knows that a good proportion blame stress for any breakthrough seizures they're having -- even when they're taking their medications, even when they're not sleep-deprived," said Dr. Steven Pacia, director of the Epilepsy Center and the division of neurology at Lenox Hill Hospital in New York City. "This study is the first to truly show there might be some activation issue in the brain that's different in patients who report this problem. I think we all know that telling patients to reduce their stress to reduce seizures is a good thing to do."

Pacia and study author Allendorfer agreed that the research needs to be replicated in larger groups of patients, which may point to new ways of controlling or treating seizures.

"Eventually, if we can characterize the stress response in patients . . . maybe this can be a way to target different kinds of therapy to help reduce seizure frequency," Allendorfer said.

While the study found an association between stress response and epileptic seizures, it did not prove a cause-and-effect relationship.

More information

The U.S. National Library of Medicine has more about epilepsy.

SOURCES: Jane B. Allendorfer, Ph.D., instructor, neurology, University of Alabama at Birmingham; Steven Pacia, M.D., director, Epilepsy Center and division of neurology, Lenox Hill Hospital, New York City; Dec. 3, 2012, presentation, American Epilepsy Society annual meeting, San Diego


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Largest coronary artery disease study shows evidence of link between inflammation and heart disease
2. Childrens Seizures Not Always Damaging, Study Finds
3. More U.S. Kids Get High-Radiation Scans, Study Says
4. Under Similar Stress, Rich Live Longer Than Poor: Study
5. U-M study shows BPA exposure in fetal livers
6. Long-Term Use of Some Antipsychotics Not Warranted in Older Adults: Study
7. Cell phone addiction similar to compulsive buying and credit card misuse, according to Baylor study
8. Depression a Key Factor in Health of Parkinsons Patients: Study
9. Certain Arthritis Patients Fare Worse After Joint Replacement: Study
10. Deep Belly Fat Could Weaken Mens Bones, Study Suggests
11. Statins Plus Exercise Best at Lowering Cholesterol, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Supports Link Between Stress, Epileptic Seizures
(Date:2/8/2016)... ... February 08, 2016 , ... The Federal ... federallabs.org . The site houses a wealth of federal resources that businesses ... the process called technology transfer (T2). As a network of over 300 federal ...
(Date:2/8/2016)... Houma, LA (PRWEB) , ... February 08, 2016 ... ... Louisiana from offices in Houma, LA, celebrates the beginning of a new charity ... raised to assist Court Appointed Special Advocates (CASA). In the belief that children ...
(Date:2/8/2016)... Minn. (PRWEB) , ... February 08, 2016 , ... ... the BantamPro L top-load case packer for pouches, bags, and flow wrapped products ... to help co-packers and specialty product manufacturers step up to semi-automatic or fully-automatic ...
(Date:2/8/2016)... ... , ... Steve Helwig & Associates Insurance & Financial, serving the families of ... up with Citizens Opposed to Domestic Abuse in support of its efforts to provide ... victimized by the fear of violence in their own homes, donations may now be ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... Delta Dental ... to help combat pancreatic cancer. , Gary D. Radine, who recently retired as president ... the American Cancer Society’s 2015 CEO of the Year , helped lead the ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016 ... the "Global Skin Protective Equipment Market 2016-2020" ... --> http://www.researchandmarkets.com/research/fqx6nz/global_skin ) has announced the addition ... 2016-2020" report to their offering. ... ) has announced the addition of the ...
(Date:2/8/2016)... 2016   Intarcia Therapeutics, Inc. today announced ... into the newly created role of Vice President, Head ... has two decades of leadership experience at leading pharmaceutical, ... academic medical center. Most recently Dr. Yee served as ... US Head Medical Officer at AstraZeneca, where he led ...
(Date:2/8/2016)... 8, 2016  The University of Michigan Health System ... that, as part of the development of four new ... hospitals in the U.S. to start using new top-of-the-line ... U-M,s chair of neurosurgery. --> Karin ... --> The BrightMatter technology from Synaptive Medical – ...
Breaking Medicine Technology: