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Study Shows Nonprescription LCD Topical Solution is More Effective than Prescription-Strength Calcipotriol Cream for Moderate Plaque Psoriasis
Date:3/10/2009

gnificantly fewer LCD-treated patients than calcipotriol-treated patients regressed to initial disease severity within 6 weeks of stopping treatment (P</=0.005).
  • PASI scores and PGA scores worsened significantly after stopping calcipotriol therapy but not after stopping LCD therapy (P</=0.05).
  • Within 6 weeks of completing treatment, LCD-treated patients reported better control of a range of psoriasis symptoms -- including scaling/flaking, redness, skin texture, itch, overall appearance, and overall discomfort -- than calcipotriol-treated patients.
  • Patients' rated LCD solution and calcipotriol cream as comparable for convenience, irritation potential, and aesthetic attributes (e.g., staining, scent).
  • Dr. Kimball said their results should be important to a wide range of psoriasis patients because they indicate that this nonprescription therapy, "has a compelling efficacy and aesthetic profile." Psoriasis experts asked to comment on the study seem to agree on its significance.

    "Because no single treatment is right for everyone, dermatologists are always looking for new ways to improve outcomes for their psoriasis patients," said Mark Lebwohl, MD, chairman of the Department of Dermatology at The Mount Sinai School of Medicine in New York. "The results of this trial suggest that LCD may be an appropriate treatment choice for psoriasis patients with mild or moderate disease."

    Jerry Bagel, MD, Windsor Dermatology, said that "a new therapy that is easy for patients to use, cosmetically preferable, and that has greater proven efficacy than a prescription medication with the safety profile of an OTC, is certainly good news for psoriasis patients."

    About PSORENT(R)

    PSORENT(R) is a new leave-on topical solution that has the proven efficacy of a prescription medication but is available OTC.
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    SOURCE NeoStrata Company, Inc.
    Copyright©2009 PR Newswire.
    All rights reserved

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