Navigation Links
Study Shows MS Patients at Most Risk for Drug-Linked Brain Illness
Date:5/16/2012

lity, and can be deadly.

In 2010, the U.S Food and Drug Administration added a new warning about the rare brain infection to Tysabri's label. The drug also is used to treat Crohn's disease.

In January, the FDA approved a test to determine the risk of brain infection in Tysabri users.

In the new study, the researchers examined various statistics to figure out which multiple sclerosis patients were at highest risk of progressive multifocal leukoencephalopathy if they take Tysabri. Blood samples of nearly 5,900 patients with multiple sclerosis were analyzed.

Just more than 1 percent of patients showed signs of exposure to the JC virus, had taken immune-suppressing drugs before Tysabri and had been on Tysabri for 25 to 48 months.

The risk for those who hadn't been exposed to the JC virus was 120 times smaller at 0.009 percent.

Patients who worry about progressive multifocal leukoencephalopathy "may think about it differently because of the low risk in that subgroup of patients," Bloomgren said.

Multiple sclerosis patients who have been exposed to the JC virus but haven't taken immune-suppressing drugs while on Tysabri may choose to continue taking the drug, said Dr. Scott Zamvil, a professor of neurology at the University of California-San Francisco.

"Patients who are on the drug don't want to come off because it's that potent of a drug," he said. "It is the most potent of the currently approved drugs."

Patients need to talk to their physicians and weigh the benefit of the medication versus the potential risk, Zamvil said.

The study appears in the May 17 issue of the New England Journal of Medicine.

More information

For more about multiple sclerosis, try the U.S. National Library of Medicine.

SOURCES: Gary Bloomgren, M.D., vice president of drug safety, and Sandr
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. Study Links Antibiotic to Slight Rise in Heart Patients Death Risk
2. U.S. Assistance to Africa Cut AIDS-Related Deaths: Study
3. Steroid Nasal Sprays Show Small Benefit for Sinusitis: Study
4. Inhaled Steroids Lead to Big Drop in Asthma Deaths at Texas Hospital: Study
5. New inflammation hormone link may pave way to study new drugs for Type 2 diabetes
6. Study highlights need for coordination of care in stage 2 and 3 rectal cancer treatment
7. 53 million Americans might have diabetes by 2025, according to a new study in Population Health Management
8. Study examines BI-RADS and MRI in predicting breast cancer
9. Self-Managing COPD Might Pose Risks, Study Suggests
10. Study finds number of battery-related emergency department visits by children more than doubles
11. UTSA study finds ovulating women perceive sexy cads as good dads
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Shows MS Patients at Most Risk for Drug-Linked Brain Illness
(Date:5/23/2013)... Science published an article about bexarotene as a ... starting point for further Alzheimer,s research. The research group ... and KU Leuven in collaboration with the group ... at Janssen Pharmaceutica, Beerse, also tested this candidate drug ... different, as were those of two American study groups. ...
(Date:5/23/2013)... being dragged to its destruction inside a cell, ... signals that thwart the development of tumor-suppressing microRNAs ... early online publication at Nature . , ... tumors, the epidermal growth factor receptor (EGFR) gums ... led by scientists at The University of Texas ...
(Date:5/23/2013)... 23, 2013 The Rottenstein Law Group ... has created the Tylenol Lawsuit Information Center at ... users and those who are considering filing lawsuits. ... potentially cause severe liver damage, according to a 2009 ... In the “safety communication,” the FDA warned consumers against ...
(Date:5/23/2013)... DC (PRWEB) May 23, 2013 The ... a great deal of control over their level of ... weight, yet far fewer are actually taking that control. ... Food Information Council (IFIC) Foundation’s 2013 Food & Health ... respondents say it’s possible to have “a great deal ...
(Date:5/23/2013)... Jeanne Ettelson, president of Beyond OCD , ... free OCD support group in Chicago. Launched in ... the group is lead by psychologists who specialize in ... group participants to learn accurate information about OCD, Cognitive ... in Beyond OCD’s support group benefit from being ...
Breaking Medicine News(10 mins):Health News:New insights contradict promising Alzheimer's research 2Health News:When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs 2Health News:When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs 3Health News:Rottenstein Law Group LLP Now Accepting Tylenol Cases, Announces New Tylenol Lawsuit Information Center 2Health News:Americans Experience “Control Gap” Regarding Their Weight, Diet, Activity Level; Rate Their Overall Diet a “B-Minus” 2Health News:Americans Experience “Control Gap” Regarding Their Weight, Diet, Activity Level; Rate Their Overall Diet a “B-Minus” 3Health News:Americans Experience “Control Gap” Regarding Their Weight, Diet, Activity Level; Rate Their Overall Diet a “B-Minus” 4Health News:Beyond OCD Support Group Marks Fifth Anniversary 2
... by youngsters with the disease , THURSDAY, July 2 (HealthDay ... to be overweight than those without the disease, increasing their ... is from a major study that explored the weight problems ... common form of the disease that usually shows up in ...
... the launch of (RED)ZONES at the first U2 360 Degrees concert ... rapturous sold out crowd of 90,000 fans. , , ... will be present throughout the U2 tour. The tickets for ... the ticket sales going to the Global Fund to help fund ...
... reports of DEA intervention are accurate, Michael Jackson,s doctors will ... won,t end there. The pharmacists who filled Mr. Jackson,s prescriptions ... name is associated with any of Jackson,s prescriptions," said attorney ... won full federal jury acquittal at trial on a 10 ...
... Cardinal Health today announced that Bruce L. Downey will ... of the planned spinoff of CareFusion Corporation, replacing John B. ... after 22 years of service to the company as a ... chairman and chief executive officer of Barr Pharmaceuticals, Inc. and ...
... the advisory committee,s recommendations to the U.S. Food and Drug Administration (FDA) ... physician leaders from the American Academy of Pain Medicine ... The American Academy of Pain Medicine ... specialty of Pain Medicine, supports the safe and responsible, ...
... the pipeline, could plug a Percocet-Vicodin gap, experts say, , ... Percocet and Vicodin, which a U.S. health advisory panel has ... medical experts contend. , The reason, they say, is that ... Administration advisory panel made its recommendation Tuesday. It followed the ...
Cached Medicine News:Health News:Kids With Type 1 Diabetes Often Overweight 2Health News:(RED)ZONES Launch at First U2 360 Degrees Concert in Barcelona 2Health News:(RED)ZONES Launch at First U2 360 Degrees Concert in Barcelona 3Health News:DEA Will Play Hardball in Investigating Michael Jackson's Doctors 2Health News:Cardinal Health Appoints Bruce Downey to Board of Directors; John McCoy Retires From Board After 22 Years 2Health News:Pain Medicine Experts Recommend Safe and Responsible Use of Acetaminophen 2Health News:If 2 Painkillers Are Banned, What Next? 2Health News:If 2 Painkillers Are Banned, What Next? 3Health News:If 2 Painkillers Are Banned, What Next? 4
(Date:5/23/2013)... May 23, 2013  Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: ... named the 2013 Life Science Firm of the Year by ... Vanda was honored at the TCM,s 25 th Annual ... Maryland.  The Tech Awards Celebration recognizes the leaders and innovators ... Maryland and the surrounding regions. ...
(Date:5/23/2013)... de mayo de 2013  Volcano Corporation (NASDAQ: ... fabricante de herramientas de precisión para terapia guiadas ... la enfermedad vascular periférica y coronaria, anunció hoy ... enosine V asodilator I ndependent ... sesión de ensayo clínico hot line late breaking ...
(Date:5/23/2013)... Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) ... and Chief Executive Officer of Neurocrine Biosciences, will be presenting ... Care Conference in Boston.   The live presentation ... Time / 8:20 a.m. Pacific Time.  The presentation will be ... http://www.neurocrine.com . If you are unable ...
Breaking Medicine Technology:Vanda Pharmaceuticals Named the 2013 Life Science Firm of the Year by the Tech Council of Maryland 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6
... (CRL) has invested in a low-dose, state-of-the-art CT machine ... Minnesota.  This advanced diagnostic system will help physicians reach ... care with a radiation dose up to 40% lower ... "The addition of the GE Healthcare Brightspeed Elite CT ...
... ECRI Institute ®, an independent ... improving patient care, today announces the launch of its ... to ECRI Institute,s SELECTplus™ healthcare technology advisory service. The ... intelligence to help hospitals and health systems select and ...
Cached Medicine Technology:Consulting Radiologists, Ltd. Announces Addition of a Low Dose Advanced Computed Tomography (CT) System 2ECRI Institute Launches Market Analytics Tool to Help Hospitals Make More Informed Capital Purchasing Decisions 2ECRI Institute Launches Market Analytics Tool to Help Hospitals Make More Informed Capital Purchasing Decisions 3
40-well gradient cycler...
... a high quality, compact thermal cycler. In addition ... Mastercycler personal offers first-rate operational flexibility. Its universal ... x 0.2 ml tubes, 16 x 0.5 ml ... grid format. Like the Mastercycler and the Mastercycler ...
... instrument and custom filter wheels with ... The standard filter set includes: FAM/SYBR ... Red (585nm-610nm), Cy5 (635nm-665nm) and Cy3 ... Mx3005P analysis software, Beacon Designer oligo ...
... The system includes: Mx3005P instrument and ... of five (5) filters. The standard ... (492nm-516nm), HEX/JOE/VIC (535nm-555nm), ROX/Texas Red (585nm-610nm), ... included: desktop computer, Mx3005P analysis software, ...
Medicine Products: