Navigation Links
Study Showing Improved Virologic Response with Nitazoxanide in Chronic Hepatitis C Published in Gastroenterology
Date:3/2/2009

Editorial Accompanies Manuscript in March Issue

TAMPA, Fla., March 2 /PRNewswire/ -- A study evaluating nitazoxanide in combination with peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C virus (HCV) infection with genotype 4 was published in the March issue of Gastroenterology, the official journal of the American Gastroenterological Association Institute (AGA Institute). The study showed that the addition of nitazoxanide to standard-of-care therapy increased the rate of sustained virologic response when compared with patients given peginterferon plus ribavirin alone.(1) An accompanying editorial commenting on the study was also published in the Journal.(2)

"The results published today in Gastroenterology represent an important milestone in the development of nitazoxanide, the first thiazolide, for the treatment of chronic hepatitis C," said Jean-Francois Rossignol, MD, PhD, Romark Institute for Medical Research, the inventor of this new class of antiviral drugs and lead author of the study. "Nitazoxanide is currently being evaluated along with the standard-of-care treatment in patients with chronic hepatitis C genotype 1 in clinical trials in the U.S., and we look forward to reporting interim data from those trials in the coming months."

Study Details

The randomized, controlled study published in Gastroenterology evaluated the safety and efficacy of nitazoxanide plus peginterferon, with or without ribavirin, in 97 patients with previously untreated genotype 4 chronic hepatitis C at 2 centers in Egypt. Participants were sequentially allocated into 3 treatment arms (one patient immediately dropped from the study):

  • Peginterferon alfa-2a 180 mcg/week plus ribavirin 1000-1200 mg/day for 48 weeks (standard of care) (n = 40);
  • Nitazoxanide 500 mg twice daily monotherapy for 12 weeks followed by nitazoxan
    '/>"/>

SOURCE Romark Laboratories
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... Documented Legacy , a mobile personal ... of its first military memoir about a World War II ... October 1943 and 19 months as a prisoner of war ... the American dream. , From the Top Turret: A ... (Amazon) is a true life story of Gerard Caporaso’s ...
(Date:7/14/2014)... 2014 The Retina Group of ... Hauppauge, NY, has announced the availability of Ozurdex® ... diabetic macular edema (DME) patients. Ozurdex, a corticosteroid ... indication for use in diabetic macular edema. Ozurdex ... for treatment of retinal vascular occlusions and and ...
(Date:7/14/2014)... 14, 2014 According to a recent ... researchers have discovered a connection between women with high ... of infertility. Although doctors have theorized about the role ... first study to provide scientific support. , “Stress, if ... said Dr. Larry Barmat, an OB/GYN who specializes in ...
(Date:7/14/2014)... 2014 Last month Bromell Agency officially ... The webpage features more detailed information on how clients ... RVs, ATVs, and boats in the state of Louisiana. ... feature to the website in order to better educate ... the purpose of the website, which is to display ...
(Date:7/14/2014)... 14, 2014 There’s an old adage that ... The Lash Palette say the products offered in their ... , “You can reserve The Lash Palette for $40,” said ... Store . , Paris explained that the first 1,000 have ... 21. , She went on to point out that her ...
Breaking Medicine News(10 mins):Health News:Mount Laurel-based Documented Legacy to Release Military Memoir of World War II Air Force Vet Who Survived Black Thursday Crash 2Health News:Retina Group of New York Now Offers Long-lasting Ozurdex® Treatment for Diabetic Retinopathy 2Health News:Retina Group of New York Now Offers Long-lasting Ozurdex® Treatment for Diabetic Retinopathy 3Health News:Abington Health Physician Addresses Link Between Stress and Infertility 2Health News:Abington Health Physician Addresses Link Between Stress and Infertility 3Health News:The Lash Palette Preorder Event Has Officially Begun 2
... , , WASHINGTON , Feb. 8 ... showed he has what it takes to win big. Not only does ... own Milk Mustache. The 13th annual winning football Milk Mustache ad runs ...   http://www.newscom.com/cgi-bin/prnh/20100208/AQ51302 ) , The famed running back is the latest superstar ...
... Nev. , Feb. 8 The Whittemore Peterson ... Donnica Moore , a distinguished women,s health expert, as its ... in its efforts to help raise awareness and funding for ... Fatigue Syndrome.   , "We are pleased to have a ...
... ... Health, a joint venture between Humility of Mary Health Partners (HMHP) , NEO ... Ohio,s first and only radiation oncology center with Elekta Volumetric Modulated Arc Therapy (VMAT), ... ...
... , , NORTHBROOK, Ill. , ... a global leader in environmental evaluation and certification, announces ... materials used in consumer and manufactured goods.  These standards ... scientific assessment and broad stakeholder collaboration.   , This ...
... the use of computed tomography (CT scans) in children ... of scans, according to a new study in ... link only) http://www.cmaj.ca/embargo/cmaj091421.pdf . More than 650,000 ... consciousness, amnesia, disorientation and/or vomiting are seen each year ...
... JRS Medical ... that the Company is donating a percentage of all of their January & February 2010 ... employees also are raising funds locally for victims of the tragic earthquake. , ... (PRWEB) February 8, 2010 -- JRS Medical ...
Cached Medicine News:Health News:Reggie Bush Takes Down Reggie Wayne in Battle for the Milk Mustache! 2Health News:Whittemore Peterson Institute Announces Renowned Health Expert as New Spokesperson 2Health News:Partners for Urology Health First in Ohio with New Radiation Therapy Technology 2Health News:Partners for Urology Health First in Ohio with New Radiation Therapy Technology 3Health News:UL Environment to Develop Sustainability Standards For Plastic 2Health News:New CATCH rule to determine need for CT scans in children with minor head injury 2Health News:JRS Medical Raises Funds for Devastated Victims in Haiti 2Health News:JRS Medical Raises Funds for Devastated Victims in Haiti 3
(Date:7/14/2014)... July 14, 2014 CVS/pharmacy ® ... PLATINUM, a premium brand of 100% preservative-free vitamins ... growing family of exclusive CVS/pharmacy store brand products. ... with various benefits, including popular options such as ... women. The radiance PLATINUM line also has more premium options ...
(Date:7/14/2014)... , July 14, 2014 The legalization of ... – as well as a new economic driver – ... to sort out the right response to the will ... intoxicant. At a National Press Club ... a.m., two leading experts in the area of marijuana ...
(Date:7/14/2014)... N.Y. , July 14, 2014 We ... Surgery Center ("OACM") and the Ellicott City Ambulatory Surgery ... of Ellicott City Maryland . ... between Merritt Healthcare and 14 leading Orthopaedics, Sports Medicine, ... Facility will also accommodate the specialties of general surgery ...
Breaking Medicine Technology:CVS/pharmacy Launches Exclusive radiance PLATINUM Line of Preservative-Free Vitamins and Supplements 2CVS/pharmacy Launches Exclusive radiance PLATINUM Line of Preservative-Free Vitamins and Supplements 3NPC Newsmaker Program: Interpreting smoke signals from the marijuana skirmish line 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: