Navigation Links
Study Sees Link Between Epilepsy, Infertility
Date:10/11/2010

MONDAY, Oct. 11 (HealthDay News) -- Women with epilepsy may be at increased risk of infertility, a study of women from India suggests.

The study included 375 women who planned to have a child, average age 26, who were followed until they became pregnant or for up to 10 years. During the study period, 62 percent of the women became pregnant.

The rate of infertility among women with epilepsy was more than twice the 15 percent rate in the general population. Women taking three or more drugs for epilepsy were 18 times more likely to be infertile than those taking no epilepsy drugs -- 60 percent versus 7 percent. Infertility rates were 41 percent for women taking two epilepsy drugs and 32 percent for those taking one epilepsy drug, the study authors found.

"This may be due to the adverse effects of taking multiple drugs or it could be a more indirect effect because people who are taking multiple drugs are more likely to have severe epilepsy that is difficult to treat," study author Sanjeev Thomas, of the Sree Chitra Tirunal Institute for Medical Sciences and Technology in Trivandrum, India, said in a news release from the American Academy of Neurology.

The researchers found that the drug phenobarbital was associated with significant risk of infertility, while no such link was noted with valproate or other drugs.

The study findings are published in the Oct. 12 print issue of the journal Neurology.

"Based on these findings, women with epilepsy should be counseled about the potential risk of infertility and referred for an evaluation if they have not conceived within two years" of trying to become pregnant, Dr. Alison M. Pack, an assistant professor of clinical neurology at Columbia University in New York City, wrote in an accompanying editorial in the journal.

Dr. Steven V. Pacia, director of the Comprehensive Epilepsy Center at Lenox Hill Hospital in New York City, said: "Certain antiepileptic medications (AEDs), including phenobarbital, may affect the metabolism of normal hormones in women with epilepsy. This effect will be enhanced at higher doses and by the addition of several other AEDS that may be expected in patients with more severe epilepsy.

"However, patients with more severe epilepsy can be expected to have a higher incidence of cognitive problems, mood disorders and hyposexuality, which may also lead to higher rates of infertility," he added.

More information

The U.S. National Women's Health Information Center has more about infertility.

-- Robert Preidt

SOURCES: American Academy of Neurology, news release, Oct. 11, 2010; Lenox Hill Hospital, news release, Oct. 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. ... his M.D from the David Geffen School of Medicine at UCLA. He trained in ... to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... , ... June 24, 2016 , ... A recent ... most people are unfamiliar with. The article goes on to state that individuals are ... many of these less common operations such as calf and cheek reduction. The Los ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016   Bay Area Lyme Foundation , ... Center for Tick Borne Illness , Harvard Medical ... Hacking Medicine, University of California, Berkeley, and the ... five finalists of Lyme Innovation , the ... 100 scientists, clinicians, researchers, entrepreneurs, and investors from ...
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
Breaking Medicine Technology: