Navigation Links
Study Sees Link Between Epilepsy, Infertility

MONDAY, Oct. 11 (HealthDay News) -- Women with epilepsy may be at increased risk of infertility, a study of women from India suggests.

The study included 375 women who planned to have a child, average age 26, who were followed until they became pregnant or for up to 10 years. During the study period, 62 percent of the women became pregnant.

The rate of infertility among women with epilepsy was more than twice the 15 percent rate in the general population. Women taking three or more drugs for epilepsy were 18 times more likely to be infertile than those taking no epilepsy drugs -- 60 percent versus 7 percent. Infertility rates were 41 percent for women taking two epilepsy drugs and 32 percent for those taking one epilepsy drug, the study authors found.

"This may be due to the adverse effects of taking multiple drugs or it could be a more indirect effect because people who are taking multiple drugs are more likely to have severe epilepsy that is difficult to treat," study author Sanjeev Thomas, of the Sree Chitra Tirunal Institute for Medical Sciences and Technology in Trivandrum, India, said in a news release from the American Academy of Neurology.

The researchers found that the drug phenobarbital was associated with significant risk of infertility, while no such link was noted with valproate or other drugs.

The study findings are published in the Oct. 12 print issue of the journal Neurology.

"Based on these findings, women with epilepsy should be counseled about the potential risk of infertility and referred for an evaluation if they have not conceived within two years" of trying to become pregnant, Dr. Alison M. Pack, an assistant professor of clinical neurology at Columbia University in New York City, wrote in an accompanying editorial in the journal.

Dr. Steven V. Pacia, director of the Comprehensive Epilepsy Center at Lenox Hill Hospital in New York City, said: "Certain antiepileptic medications (AEDs), including phenobarbital, may affect the metabolism of normal hormones in women with epilepsy. This effect will be enhanced at higher doses and by the addition of several other AEDS that may be expected in patients with more severe epilepsy.

"However, patients with more severe epilepsy can be expected to have a higher incidence of cognitive problems, mood disorders and hyposexuality, which may also lead to higher rates of infertility," he added.

More information

The U.S. National Women's Health Information Center has more about infertility.

-- Robert Preidt

SOURCES: American Academy of Neurology, news release, Oct. 11, 2010; Lenox Hill Hospital, news release, Oct. 11, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... While it’s ... poses a problem. Fortunately, an inventor from Austin, Texas, has identified a solution. , ... medication in darkness or restricted lighting. As such, it eliminates the need to turn ...
(Date:10/13/2017)... ... , ... Lori R. Somekh, founder of the Law Office of Somekh ... law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up ... network with elder law attorneys nationwide,” said Somekh. , ElderCounsel was ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th ... Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, ... The fun run is geared towards children of all ages; it is a non-competitive, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the ... “America On The Brink” is the creation of published author, William Nowers. Captain ... As a WWII veteran, he spent thirty years in the Navy. Following his ...
(Date:10/12/2017)... ... 2017 , ... IsoComforter, Inc. ( ), one of the ... new design of the shoulder pad. The shoulder pad provides optimal support and ... pain while using cold therapy. By utilizing ice and water that is circulated from ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... , Oct. 6, 2017   Provista, a ... than $100 billion in purchasing power, today announced a ... information. The Newsroom is the online home ... trends, infographics, expert bios, news releases, slideshows and events. ... to a wealth of resources at their fingertips, viewers ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
(Date:10/2/2017)... , Oct. 2, 2017 Halo Labs announces the European ... system called the HORIZON at MIBio 2017 in Cambridge, ... and visible particulate matter in biopharmaceutical samples with unprecedented speed and ... the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: