Navigation Links
Study Reports Progress Against Fatal Brain Cancer
Date:2/24/2010

In mice, researchers discover new way to prevent recurrence of glioblastoma

WEDNESDAY, Feb. 24 (HealthDay News) -- A new method to prevent recurrence of deadly glioblastoma brain cancer shows promise, say U.S. scientists.

Radiation can temporarily shrink a glioblastoma tumor, but the cancer nearly always recurs within weeks or months. Few people with this type of brain cancer survive more than two years after diagnosis.

In a study on mice, Stanford University School of Medicine researchers found that blocking access to oxygen and nutrients prevents tumor recurrence.

The first step, they said, was discovering that tumors blasted with radiation use a secondary pathway to generate blood vessels needed for regrowth.

"Under normal circumstances, this pathway is not important for growth of most tumors," senior author Martin Brown, a professor of radiology, said in a Stanford news release. "What we hadn't realized until recently is that radiation meant to kill the cancer cells also destroys the existing blood vessels that nourish the tumor. As a result, it has to rely on a backup blood delivery pathway."

The Stanford team used a molecule called AMD3100 to block the secondary glioblastoma tumor growth process in mice.

The study was published online Feb. 22 in the Journal of Clinical Investigation.

AMD3100 is already approved for different uses in humans so it's possible that clinical trials to test the molecule in glioblastoma patients could take place soon, according to the researchers. However, any routine use of AMD3100 or similar molecules to treat glioblastoma is likely still years away, they added.

In their study, the Stanford team focused on glioblastoma, but other tumors use a similar secondary blood delivery pathway to survive radiation treatment.

More information

The U.S. National Cancer Institute has more about

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Study Suggests Low-Consuming Medicare Beneficiaries With Chronic Disease Are More Costly to Program
2. Midlife crisis: Unmarried older women twice as likely to lack health insurance, study shows
3. Canadian researchers study mass gatherings and risks of infectious disease threats
4. Psychiatrys main method to prevent mistaken diagnoses of depression doesnt work: NYU study
5. Study Shows Sani-Bag+ to be an Effective Microbial Barrier
6. Visual Cues that Improve Walking for People with Movement Disorders - Study Shows Small Change in Arrangement Can Make a Big Difference in Improvement Gained
7. New Heart CT Scans Deliver Far Less Radiation: Study
8. Researchers receive NIH grant to study predictors and outcomes of autoimmune lung disease
9. Scott & White Healthcare pathologist is co-investigator on breast cancer study
10. Mayo oral cancer study shows full tumor genome
11. New study reveals long delays and variability are losing the UK research and jobs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... 2015 On April 14th, 2015, Symantec released ... which they say, “exposes a tactical shift by cyberattackers.” With ... were introduced in 2014 - almost a million a day ... to be identified and patched by prominent manufacturers – as ... doing business in a digital world can be fraught with ...
(Date:4/18/2015)... FL (PRWEB) April 18, 2015 PHOENIX, ... Hillsborough County, along with 11 other secure destruction professionals ... Secure Destruction Specialists (CSDS). He will now display “CSDS” ... exams were offered before the National Association of Information ... Illinois and another Grapevine, Texas. Of the 20 people ...
(Date:4/17/2015)... 2015 John Evans, a Gardant affordable ... Patio from 2 p.m. to 3 p.m. on April ... Executive Ct. in Pekin, Illinois, serves older adults of ... help to maintain their independence. , Becky Baker will ... will be served during the luau. , For more ...
(Date:4/17/2015)... Newport Beach, California (PRWEB) April 17, 2015 ... plastic surgeon Dr. Kevin Sadati of the ... one of Orange County’s top beauty experts. The ... and neck lift, facial stem cell fat grafting, eyelid ... approach to facial plastic surgery has resulted ...
(Date:4/17/2015)... have seen healing, a lot of healing, and a lot ... Kafader of Friendship Village. “People have found purpose. ... have created beautiful pieces of art.” For the past eight ... was launched to benefit residents of the retirement community. , ... Institute in Chicago, worked as an intern at Friendship Village, ...
Breaking Medicine News(10 mins):Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 4Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 5Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 3Health News:Healing At Friendship Village Due To Art Therapy 2
... ON (January 28) Diagnosing a nasty cough is ... developed at McMaster University, which has just been approved ... in the United States. , This new test simultaneously ... the common cold, helping doctors more accurately diagnose patients. ...
... biologically younger than couch potato set, British study ... People who are physically active in their free ... a new British study suggests. , "A sedentary ... premature death. Inactivity may diminish life expectancy not ...
... guiding the biopsy of suspicious breast cancer lesions is ... of the smallest ones detected by standard imaging systems, ... initial testing of the PEM/PET system, designed and constructed ... National Accelerator Facility, West Virginia University School of Medicine ...
... Morphines serious side effect as a pain killer its ... in research with mice by genetically modifying a single trait ... drug can be developed to similarly block dependency. , ... and appears in the journals January 23 print edition. The ...
... Forgetful Casanovas are lucky in love. , At least ... of new research on the mating habits and nervous ... which examined both the voles behavior and their brains, ... the National Academy of Sciences. , Prairie voles, aka ...
... unknown, researchers say , , MONDAY, Jan. 28 (HealthDay News) ... was associated with the development of chronic bronchitis, but ... "The mechanisms underlying the association between snoring and chronic ... the Jan. 28 issue of Archives of Internal ...
Cached Medicine News:Health News:McMaster test detects the most prevalent respiratory viruses 2Health News:Sedentary Lifestyle Accelerates Aging 2Health News:Device zeroes in on small breast tumors 2Health News:Morphine dependency blocked by single genetic change 2Health News:Zoologists: Lusty voles, mindless of danger, mate like rabbits 2Health News:Zoologists: Lusty voles, mindless of danger, mate like rabbits 3Health News:Study Links Snoring to Chronic Bronchitis 2
(Date:4/17/2015)... CAMBRIDGE, England , April 17, 2015 ... cancer genomics company announced today that their presence at the ... will include a presentation by co-founder Nitzan Rosenfeld ... is also attending April 18 th - 22 nd ... genome in plasma using ctDNA , forms part ...
(Date:4/17/2015)... , Apr. 17, 2015 Research and Markets ... of the "Medical Equipment Rental and Leasing - ... This report analyzes the worldwide markets for ... report provides separate comprehensive analytics for the US, ... and Rest of World. Annual estimates and ...
(Date:4/17/2015)... , April 17, 2015  Trovagene, Inc., ... announced today that clinical data presented at the ... its urine-based Precision Cancer Monitoring ℠ (PCM) ... monitoring of EGFR T790M mutations in ... Detection of EGFR T790M Mutation in Urinary Circulating ...
Breaking Medicine Technology:Inivata Co-founder Nitzan Rosenfeld to Present at AACR Annual Meeting 2Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 4
... (Nasdaq: CPHD ) today announced that ... investor conferences, and invited investors to participate via ... 15, 2010 at 10.30 a.m. Eastern TimeStifel Nicolaus ... 10.55 a.m. Eastern TimeUBS Global Life Sciences Conference, ...
... Reportlinker.com announces that a new market research report ... Diagnostic Imaging Market to 2016 - Nuclear Imaging ... Revenue Generators http://www.reportlinker.com/p0286302/Diagnostic-Imaging-Market-to-2016---Nuclear-Imaging-Systems-and-Ultrasound-Systems-to-be-the-Key-Revenue-Generators.html ... - Nuclear Imaging Systems and Ultrasound Systems to ...
Cached Medicine Technology:Cepheid to Webcast Upcoming Financial Presentations 2Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 2Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 3Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 4Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 5Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 6Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 7Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 8Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 9Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 10Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 11Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 12Reportlinker Adds Diagnostic Imaging Market to 2016 - Nuclear Imaging Systems and Ultrasound Systems to be the Key Revenue Generators 13
... Ultra MD Super Pulse sealed CO2 ... versatility backed by the experience and support ... years of surgical laser experience. All settings ... finger. The Ultra MD Super Pulse surgical ...
The compact size and portability of the Epic system makes it a cost-effective solution for single or multi-office use....
A soft contact lens that lets presbyopes see clearly and comfortably at all distances , without the hassles of bifocals or reading glasses. Recommended for daily wear. Also approved for extended wear...
... display of corneal layers: endothelium, ... epithelial layers. Accurate analysis of ... keratocytes, nerve fibres, basal & ... surgery and pathology: optical pachymetry, ...
Medicine Products: