Navigation Links
Study Questions Flu Shot's Value for Older People
Date:9/25/2007

Most trials don't even include people over 70, researchers note

TUESDAY, Sept. 25 (HealthDay News) -- The ability of flu shots to reduce the risk of influenza-related death among people 65 and older may be greatly exaggerated, say researchers who reviewed the available scientific evidence.

This exaggeration is the result of "frailty selection bias" -- where not-so-frail older people are vaccinated more often than those who are infirm, the team said. It's also due to the use of non-specific clinical trail endpoints, such as death from any and all causes, wrote a group led by Dr. Lone Simonsen, of George Washington University in Washington, D.C.

They reported their conclusions in the October issue of The Lancet Infectious Diseases journal.

The researchers noted that few clinical trials of flu vaccines have included seniors, especially those aged 70 and older -- the age group that accounts for 75 percent of all influenza-related deaths. Those studies that have been conducted with seniors suggested a steady decline in clinical benefits and vaccine antibody responses after age 70.

The review authors also found that, even though vaccination rates increased from 15 percent to 65 percent since 1980, studies have not been able to confirm a corresponding decline in flu-related deaths.

"Paradoxically, whereas those studies attribute about five percent of all winter deaths to influenza, many cohort studies report a 50 percent reduction in the total risk of death in winter -- a benefit ten times greater than the estimated influenza mortality burden," the review authors wrote.

Future studies on flu vaccines in older groups should use more specific endpoints and actual virus surveillance data for each flu season, rather than the current arbitrary four-month period, the team added.

Despite the current lack of evidence, the review authors do recommend that seniors continue to get flu shots.

"While awaiting an improved evidence base for influenza vaccine mortality benefits in elderly people, we suggest that this group should continue to be vaccinated against influenza. Influenza causes many deaths each year, and even a partly effective vaccine would be better than no vaccine at all," they said. "But the evidence base concerning influenza vaccine benefits in elderly people does need to be strengthened."

More information

The U.S. National Institute on Aging has more about older people and the flu.



-- Robert Preidt



SOURCE: The Lancet, news release, Sept. 25, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... , ... May 04, 2016 , ... ... announced that they acquired Pocono Sterilizer, an equipment sterilization service and sales company ... Service currently provides medical and research-related equipment and asset management services to the ...
(Date:5/4/2016)... Trumbull, Connecticut (PRWEB) , ... May 04, 2016 , ... Netc , a leading ... Dataware Labels from Art Style Printing, Inc. The Dataware acquisition enables Netc to continue to ... combined with Netc Blank Label Stock provides customers with the ability to print and label ...
(Date:5/3/2016)... ... May 03, 2016 , ... According to an article ... issues related to medical care in the hospital setting, which include excessive wait ... hospital staff. Commenting on this article, the founder of House Call Doctor Los ...
(Date:5/3/2016)... ... May 03, 2016 , ... For over 23 years, Doctors ... build the leading network of doctors and therapists treating personal injury patients on a ... distinguished Bay Chiropractic and Rehabilitation in Santa Monica, Doctors on Liens is ...
(Date:5/3/2016)... Yorba Linda, CA (PRWEB) , ... May 03, ... ... exponential enrichment) is a process that selects DNA or RNA from a random ... ligands—called aptamers—could potentially be used as drugs or diagnostic agents. SELEX selection is ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... 3, 2016  While you may be familiar with watching a film or TV show in ... ultra-high-definition or 8MP in the Medical Industry.  Ampronix  is a renowned authorized reseller of the ... Photo - http://photos.prnewswire.com/prnh/20160502/362730 ... ... ...
(Date:5/3/2016)... Mich. , May 3, 2016   Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that ... company released a video of two patients who tell their personal story and encourage those ... Meet Jacque: Hepatitis C ... ... Diplomat Specialty Pharmacy (PRNewsFoto/Diplomat Pharmacy, Inc.) ...
(Date:5/3/2016)... , May 3, 2016 According ... Size, Share, Development, Growth and Demand Forecast to 2022 ... Field Strength (High Field, Very High Field, Low to ... Head and Neck, Spine, Musculoskeletal, Vascular, Breast, Pelvic and ... magnetic resonance imaging (MRI) market was valued at $5,351.7 ...
Breaking Medicine Technology: