Navigation Links
Study Puts 1 Alzheimer's Theory in Doubt
Date:8/20/2007

Results in mice suggest a key gene might not be to blame, researchers say

MONDAY, Aug. 20 (HealthDay News) -- Research with mice is poking holes in a prevailing theory on the origins of Alzheimer's, scientists say.

Mice without a gene thought to rein in cell-damaging free radicals actually had fewer Alzheimer's-linked brain plaques than mice with the gene.

"This finding may go beyond Alzheimer's into all aging theory," noted lead researcher Carlos T. Moraes, an associate professor of neurology and cell biology and anatomy at the University of Miami Miller School of Medicine.

The study is published in this week's early edition of the journal Proceedings of the National Academy of Sciences.

Moraes said that, right now, "nobody knows what causes Alzheimer's disease," which affects more than 4.5 million Americans according to the National Institutes of Health.

However, one leading hypothesis is that there is a defect in the mitochondrial energy production system in cells, Moraes explained. The mitochondria are the cell's "power houses," giving it the energy it needs to function.

In prior studies, examination of the brain cells of people with Alzheimer's found some defects in an enzyme produced by the cytochrome c oxidase (COX) gene, which is important for mitochondrial energy production.

In addition, so-called "free radicals," which cause oxidative stress, are produced in the cell's mitochondria, Moraes noted. "It was assumed that when you have a problem with the COX gene, you have more free radicals being formed," he said.

To see how the gene worked, Moraes's group removed the COX10 gene in mice engineered to develop Alzheimer's disease.

"We expected to see that these animals would have more amyloid plaques," Moraes said. "But we got the opposite result," he said.

The animals without the COX10 gene actua
'/>"/>


Copyright©2007 ScoutNews,LLC.

Page: 1 2 3

Related medicine news :

1. Gene study links endometriosis, infertility
2. Study reveals how stress can make you sick
3. Study points out that HIV vaccine may not be accepted easily
4. A new study surpasses Gene Therapy Hurdle
5. Tomato Sauce reduces Cancer Risk- Study
6. A question on study of Adult Stem Cell
7. Study on obesity and heart failure
8. National Lung Study in the process
9. Marijuana gateway theory strengthened by study of twins
10. Old theory of adaptation confirmed by new study
11. Study casts doubt on keyboard ills
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2014)... November 22, 2014 Discount-Dress.com is ... of the firm is to increase the company’s online market ... a new selection of bridesmaid dresses and announced a bridesmaid ... is valid until Dec. 30, 2014. All the dresses from ... inexpensive. , In fact, Discount-Dress.com is very good at ...
(Date:11/22/2014)... "My friend went in for a mammogram and ... an inventor from Cambria Heights, N.Y. "To add insult ... time because the first results were inaccurate. Her misfortune ... MAMO EASY to offer a more comfortable way to ... from the pain normally involved with this procedure. The ...
(Date:11/22/2014)... (HealthDay News) -- The wide variety and complexity of ... for people with food allergies, an expert warns. ... types of food allergies that it can be really ... Guha Krishnaswamy, director of allergy and clinical immunology at ... news release. "If you know you have food ...
(Date:11/22/2014)... This month has been a historical time ... received many positive reviews from some renowned review websites. Recently, ... by launching a new selection of wonderful sexy wedding dresses ... enjoy free shipping and up to an 80% discount on ... always find the most suitable dress at Angeldress.co.uk, which has ...
(Date:11/22/2014)... Petersburg, FL (PRWEB) November 22, 2014 ... Kitchen Innovations are pleased to announce that Ashley ... the Thanksgiving #PayItForward contest. , Ms. Lombardo entered ... from Kitchen Innovations. She wrote of how her friend ... young daughters as a single mom. Despite medical bills ...
Breaking Medicine News(10 mins):Health News:Bridesmaid Dresses Introduced by Famous Company Discount-Dress.com For The New Year 2015 2Health News:'Tis the Season of Challenges for Those With Food Allergies 2Health News:Sexy Wedding Dresses with Special Discounts Launched by Angeldress.co.uk 2Health News:Forbes Living TV Announces Winner of Thanksgiving #PayItForward Contest 2
... will now be possible for a patient with spinal cord ... moving the paralyzed limbs// , as signals to an implanted ... enable the user to operate mechanical devices with the help ... in the July 13 issue of Nature includes the first ...
... in the United States are screened for more than ... of Dimes and the American Academy of Pediatrics have ... Genetics calling for expanded screening for 29 disorders, including ... health expert Russell Kirby, Ph.D., agrees. “All of these ...
... nature when seeking to achieve the effects of the male ... root of the wild Mpesu tree (Securidaca Longepeduculata) found in ... Park along the border with Zimbabwe is said to be ... and consumed with tea and other traditional drinks has been ...
... abortions every year and over 80 percent of pregnant women ... year 6.7 million abortions take place in India but the ... and technique used in most of the illegal cases are ... Sanstha, an NGO working closely with the Ministry of Health ...
... An intermittent treatment with sulfadoxine-pyrimethamine, a common and cheap ... children //by Rafael Pardo, director of the Fundación BBVA, ... Health of Hospital Clínic de Barcelona. The findings of ... issue of the Journal of Infectious Diseases. ...
... a technique of kidney transplantation using human embryonic stem ... rejection// but also cuts treatment cost dramatically. ,Researchers ... of rejection of the kidney transplanted in the recipient. ... that leave them vulnerable to infections as they lower ...
Cached Medicine News:Health News:A boon to the paralyzed -Brain Gate Neural Interface System 2Health News:Over Five Million Illegal Abortions In India Every Year 2Health News:Intermittent Treatment Found Effective In Malaria 2Health News:Intermittent Treatment Found Effective In Malaria 3Health News:Intermittent Treatment Found Effective In Malaria 4Health News:Intermittent Treatment Found Effective In Malaria 5Health News:Indian doctor's new stem cells technique for kidney transplant 2
(Date:11/22/2014)... HILL, N.C. , Nov. 21, 2014 /PRNewswire/ ... healthcare system. Undoubtedly, the growing influence of patients ... spend for marketing interactions. Now, more than ever, ... retain patients for medical products is essential. ... firm, Best Practices, LLC, benchmarked companies spent about ...
(Date:11/21/2014)... Va. , Nov. 21, 2014  Alta Home ... Southern California , today announced a ... Alta will be providing the innovative BeClose system to ... Logo - http://photos.prnewswire.com/prnh/20141121/160143LOGO ... the kind of affordable 24/7 care our clients need ...
(Date:11/21/2014)... Nov. 21, 2014   Rock Creek Pharmaceuticals, Inc., ... Company is scheduled to present at the Biotech Showcase™ ... on January 12-14, 2015. ... of Rock Creek Pharmaceuticals, will present preclinical and clinical ... which exhibits anti-inflammatory pharmacological characteristics. Dr. Mullan will outline ...
Breaking Medicine Technology:New Report Details Importance of Adopting a "Patient Journey" Framework in Marketing 2Alta Home Care, Inc. and BeClose Partner to Enable Seniors to Remain in Their Homes Safely and Securely 2Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 2Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 3Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 4
... China and ROCKVILLE, Md., Jan. 26, 2011 /PRNewswire-Asia/ -- Synutra ... formula company in China and a producer, marketer and seller ... that it plans to release its financial results for the ... 2011 after market close. The Company will ...
... PRINCETON, N.J., Jan. 26, 2011 Covance Inc. (NYSE: ... its fourth quarter ended December 31, 2010 of $0.45 ... $0.22 per diluted share in costs from the previously-announced ... of $0.11 per diluted share from favorable income tax ...
Cached Medicine Technology:Synutra to Announce Third Quarter Fiscal 2011 Financial Results 2Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 2Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 3Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 4Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 5Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 6Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 7Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 8Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 9Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 10Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 11Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 12Covance Reports Fourth Quarter Revenue of $492 Million, GAAP EPS of $0.45, and Pro Forma EPS of $0.56 13
... offers protection in three ... values with lightweight comfort ... quality. Lenses provide .75 ... are anti-reflection coated and ...
... Special Protective Apron is made to ... a sterile gown. Uniquely it can ... field. Reaching through the back of ... released, and the protective apron will ...
... coat apron, weight is distributed uniformly ... comfortable wear without fatigue. Made to ... front closing special procedure apron comes ... that make it a cinch to ...
... feature a 2 adjustable belt buckle. You adjust ... the Apron off your shoulders. And now theres ... the female anatomy. ,For additional back support try ... reduce pressure on the vertebrae and help lift ...
Medicine Products: