Navigation Links
Study Probes Potential Link Between Welding, Parkinson's Disease
Date:4/6/2011

WEDNESDAY, April 6 (HealthDay News) -- Manganese in welding fumes may affect welders' brains over time, according to a new, small study.

Previous research has found a link between manganese and neurological disorders, including Parkinson's disease-like symptoms.

This study included 20 welders with no symptoms of Parkinson's disease, 20 Parkinson's disease patients who were not welders, and 20 healthy people who were not welders. The welders worked at shipyards and a metal fabrication plant in the Midwest and had an average of 30,000 hours of lifetime welding exposure. Their average manganese levels were two times the upper limits of normal.

All 60 participants underwent brain PET and MRI scans and motor skills tests, and were examined by a movement disorder specialist.

Compared to non-welders, the welders had an average 11.7 percent reduction in a marker of the neurotransmitter dopamine in the same area of the brain affected by Parkinson's disease. Dopamine helps nerve cells communicate.

The researchers also found that welders had mild movement disorders. However, the results merely show an association, not cause and effect.

"There are over one million workers who perform welding as part of their job functions in the United States," study author Dr. Brad A. Racette of the Washington University School of Medicine in St. Louis said in a journal news release. "If a link between neurotoxic effects and these fumes were proven, it would have a substantial public health impact for the U.S. workforce and economy," he said.

But one expert said it's too early to draw firm conclusions from the study.

"The dopaminergic reductions [observed] were not as dramatic as those seen in Parkinson's disease patients nor was the nature of the reduction exactly like that typically seen in Parkinson's," said Dr. Michael Pourfar, director of the division of movement disorders at North Shore-LIJ Health System, Great Neck, NY. He agreed that right now, all the findings suggest is an association with dopamine function.

"That is to say, exposure to manganese may affect dopamine function and cause a parkinsonian syndrome but it does not clearly cause the same classic Parkinson's that most people are familiar with," Pourfar said. "The number of subjects in the study was relatively small and prior PET studies have not consistently demonstrated the same findings, so many questions remain about the nature of the association between manganese and parkinsonism," he added.

The study appears online April 6 in the journal Neurology.

More information

We Move has more about Parkinson's disease.

-- Robert Preidt

SOURCE: Michael Pourfar, MD, director, Division of Movement Disorders, North Shore-LIJ Health System, Great Neck, NY; Neurology, news release, April 6, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Refusal skills help minority youths combat smoking, study finds
2. Children relate to stepparents based on perceived financial, emotional benefits, study finds
3. New drug shrinks cancer in animals, U-M study shows
4. An international study in China finds strawberries may slow precancerous growth in the esophagus
5. Study: Socioeconomics playing reduced role in autism diagnoses
6. Babies Born to Obese Moms Face Higher Death Risk: Study
7. Elevated levels of sodium blunt response to stress, study shows
8. NIH, USU study maps hotspots of genetic rearrangement
9. Soy Foods OK After Breast Cancer: Study
10. Grant helps UT Southwestern researcher study causes of preterm birth
11. Penn study sheds light on end of life management of implanted defibrillators
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Probes Potential Link Between Welding, Parkinson's Disease
(Date:7/20/2017)... ... ... ChenMed , a leading provider of value-based care for seniors, today announced ... Chief Medical Officer. Dr. McCarter, formerly Associate Professor of Family Medicine at the ... for the UVA Health System, brings 30 years of highly relevant experience to his ...
(Date:7/20/2017)... ... July 20, 2017 , ... For individuals with extended ... The adjustable beds used in such facilities are specially designed to accommodate patients with ... support. , An inventor from Rochester, Ind., has invented the patent-pending PORTABLE ARM ...
(Date:7/20/2017)... ... July 20, 2017 , ... Vixiar Medical, Inc. , ... systems for monitoring cardiopulmonary diseases, announced today that it has raised seed round ... submissions and fund final engineering and initial production of the Company’s first product, ...
(Date:7/20/2017)... ... July 20, 2017 , ... TCGRx announced ... its existing adherence automation lines. The ATP® Mini and InspectRx® Mini ... TCG’s standard products, but at a size and price point that can help ...
(Date:7/20/2017)... ... July 20, 2017 , ... A budget proposal to switch ... of - living - adjustment (COLA) is a bad deal for older and disabled ... price index (CPI) would grow even more slowly than the conventional one that is ...
Breaking Medicine News(10 mins):
(Date:7/14/2017)... International plc (NASDAQ: ENDP ) will announce its second-quarter ... senior management team will host a conference call and webcast before ... The dial-in number to access the call is U.S./ ... is 45397076. Please dial in 10 minutes prior to the scheduled ... of the call will be available from August 8, 2017 at ...
(Date:7/12/2017)... 2017 CarpalAID is a revolutionary new product that relieves ... Carpal tunnel syndrome affects more than 8 million people a ... of men. The common methods of treating CTS are painful surgery, ... braces or gloves. ... CarpalAID is a clear patch worn on the palm ...
(Date:7/11/2017)... , July 11, 2017  Sysmex America, Inc., ... diagnostic testing equipment as well as middleware information ... way to make quality assurance easier and more ... is well known for the innovation that it ... Monitor elevates quality assurance processes to a new ...
Breaking Medicine Technology: