Navigation Links
Study Probes Difference Between Embryonic, Adult Stem Cells
Date:10/10/2007

Each develops in unique ways, researchers say

WEDNESDAY, Oct. 10 (HealthDay News) -- Adult stem cells lack a protein called Oct4, which helps maintain embryonic stem cells in an undifferentiated state, U.S. researchers report.

The findings suggest that the ability of stem cells to change into any kind of cell is regulated differently in adult and embryonic stem cells, the researchers said. The study also challenges findings from more than 50 studies that concluded that Oct4 was present in adult stem cells.

Using three independent detection methods to analyze six types of tissue in which Oct4-positive adult stem cells have been reported, the authors of the new study concluded that Oct4 was not present, or was present at only statistically insignificant levels, in these tissues.

The researchers at the Whitehead Institute for Biomedical Research in Cambridge, Mass., also found that Oct4 is not required to maintain mouse adult stem cells in their undifferentiated state and that adult tissues functioned normally when the Oct4 gene was deleted.

The study was published online Oct. 10 in the journal Cell Stem Cells.

Earlier studies may have misapplied analytical techniques or worked with cell cultures that had spent too much time in an incubator, said author Christopher Lengner, a postdoctoral fellow at the Whitehead Institute.

He and his team are now studying the mechanisms used by adult stem cells to change into any kind of cell.

"Is there a common pathway that governs stemness in adult stem cells, or does each stem cell have its own pathway? We don't know yet," Lengner said in a prepared statement.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... 05, 2015 On March 2, 2015, ... Labiaplasty on the Rise, Plastic Surgeons Say,” that comments ... Society for Aesthetic Plastic Surgery and the ... reported a year-over-year doubling of surgical butt augmentations performed ... in the article, this increase can be attributed to ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 ... in healthcare communications and education, announced today its ... (AMP), the nation’s only medical conference designed for ... ischemia and lower limb amputation due to vascular ... family of innovative, evidence-based publications and CME activities ...
(Date:3/5/2015)... March 05, 2015 Supply & Demand ... listing of “Pros to Know” in the supply chain ... members of MEBC’s leadership team were included on this ... and received this award due to their hard work, ... methods for meeting and resolving client needs and challenges. ...
(Date:3/5/2015)... 2015 Leading nutritional supplement provider ... Sports Festival and Arnold Fitness EXPO in ... will host a display booth featuring free samples of ... its highly-popular, class-leading fat burner Synedrex. The company will ... that utilize its top-of-the-line supplements and miniature action figures ...
(Date:3/5/2015)... OAK BROOK, Ill. (PRWEB) March 05, 2015 ... It may be even tougher to get them to brush ... more than 1,300 parents released today by Delta Dental(1) in ... half of parents (45 percent) say getting kids to brush ... get their kids to do. That’s slightly higher than getting ...
Breaking Medicine News(10 mins):Health News:The Kim Kardashian and Jennifer Lopez Effect: Butt Augmentations Double from 2013 to 2014 2Health News:HMP Holdings Acquires The Amputation Prevention Symposium (AMP) 2Health News:HMP Holdings Acquires The Amputation Prevention Symposium (AMP) 3Health News:MEBC Leaders Awarded Supply Demand Chain Executive Pros to Know Title For 2015 2Health News:Metabolic Nutrition Exhibiting at 2015 Arnold Sports Festival and Fitness EXPO This Week 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 3
... on XM Satellite Radio,and The United States Army ... new 13 week programming series designed to highlight ... internal,medicine, medical education and much more., This ... medical,professionals and those interested in a career in ...
... are a tremendous,hardship for everyone they affect, but ... can be even more catastrophic., Listen to ... Association of,Clinical Endocrinologists at:, http://media.medialink.com/WebNR.aspx?story=35281 , Registered ... for free and unrestricted use at http://www.mediaseed.tv ...
... Colonial Life & Accident,Insurance Company has set up dedicated phone lines ... Midwest to get support from the,company., (Logo: http://www.newscom.com/cgi-bin/prnh/20080109/CLW033LOGO ... free at these,numbers:, Policyholders: ... ...
... Increase Would Generate More Than $150 Million in New ... leaders,begin working next week to resolve a projected state ... $1 cigarette tax increase would,raise more than $150 million ... youth smoking, cause many smokers to quit, reduce,tobacco-related health ...
... in 8,000 deaths, 56,000 hospitalizations for those 65 and ... (HealthDay News) -- In 2005, traumatic brain injuries (TBIs) ... 56,000 hospitalizations among Americans age 65 and older, according ... study. , TBIs accounted for 50 percent ...
... determine the anti-inflammatory value of diets rich in some ... have found that a molecule produced by the body ... distress in laboratory mice. The research, supported by the ... the National Institutes of Health, was led by a ...
Cached Medicine News:Health News:The United States Army Medical Department Announces the Launch of an Innovative New Programming Series Called 'The Strength to Heal' That Will Run on ReachMD XM 157 - The Channel for Medical Professionals on XM Radio. 2Health News:The United States Army Medical Department Announces the Launch of an Innovative New Programming Series Called 'The Strength to Heal' That Will Run on ReachMD XM 157 - The Channel for Medical Professionals on XM Radio. 3Health News:Support Numbers for Colonial Life & Accident Insurance Company Customers Affected by Floods 2Health News:New Report: Increasing Mississippi's Cigarette Tax Will Reduce Smoking, Save Lives and Save Money 2Health News: Senior Falls Can Lead to Brain Injury 2
(Date:3/5/2015)... 05, 2015 Research and Markets ... the "Global Pharma US & EU Outlook ... Major Role In Shaping Up Business for Large ... Strategy Diversification Divested: Productivity measurements, ... position- Will accelerate Next wave of targeted acquisition ...
(Date:3/5/2015)... Research and Markets ( http://www.researchandmarkets.com/research/5sqnn3/global_rising ) ... Stars Outlook 2015" report to their offering. ... sought after with fresh vigor as new targets , ... poised to bring a paradigm change in the way ... Stem cell therapy/Regenerative Medicine space. The number ...
(Date:3/5/2015)... Ascendis Pharma A/S, a clinical stage ... to address significant unmet medical needs, today announced ... 2015 conference being held at the San Diego ... Thursday, March 5, 2015 during the Pediatric Endocrinology—Clinical/Translational ... and are titled: TransCon ...
Breaking Medicine Technology:Global Pharma US & EU Outlook 2015: First -In-Class Innovations and Cost Optimization Plays Major Role In Shaping Up Business for Large Cap Pharmaceutical Companies 2Global Pharma US & EU Outlook 2015: First -In-Class Innovations and Cost Optimization Plays Major Role In Shaping Up Business for Large Cap Pharmaceutical Companies 3Global Pharma Rising Stars Outlook 2015 2Ascendis Pharma to Present at ENDO 2015 2
... The Featured Products are ... Mediflex and are offered ... in regular or extra ... equipped with insulation, flush ...
... AEM Laparoscopic Instruments incorporate a layered design ... shielded and monitored to prevent stray electrosurgical ... caused by insulation failure or capacitive coupling; ... shield built into all AEM Instruments provides ...
... The 5mm AEM Laparoscopic Instruments incorporate a ... Instruments are shielded and monitored to prevent ... the instrument caused by insulation failure or ... The protective shield built into all AEM ...
... incorporate a layered design unique in the ... to prevent stray electrosurgical burns along the ... failure or capacitive coupling; a well-documented patient ... all AEM Instruments provides a neutral return ...
Medicine Products: