Navigation Links
Study Probes Difference Between Embryonic, Adult Stem Cells
Date:10/10/2007

Each develops in unique ways, researchers say

WEDNESDAY, Oct. 10 (HealthDay News) -- Adult stem cells lack a protein called Oct4, which helps maintain embryonic stem cells in an undifferentiated state, U.S. researchers report.

The findings suggest that the ability of stem cells to change into any kind of cell is regulated differently in adult and embryonic stem cells, the researchers said. The study also challenges findings from more than 50 studies that concluded that Oct4 was present in adult stem cells.

Using three independent detection methods to analyze six types of tissue in which Oct4-positive adult stem cells have been reported, the authors of the new study concluded that Oct4 was not present, or was present at only statistically insignificant levels, in these tissues.

The researchers at the Whitehead Institute for Biomedical Research in Cambridge, Mass., also found that Oct4 is not required to maintain mouse adult stem cells in their undifferentiated state and that adult tissues functioned normally when the Oct4 gene was deleted.

The study was published online Oct. 10 in the journal Cell Stem Cells.

Earlier studies may have misapplied analytical techniques or worked with cell cultures that had spent too much time in an incubator, said author Christopher Lengner, a postdoctoral fellow at the Whitehead Institute.

He and his team are now studying the mechanisms used by adult stem cells to change into any kind of cell.

"Is there a common pathway that governs stemness in adult stem cells, or does each stem cell have its own pathway? We don't know yet," Lengner said in a prepared statement.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Whitehead Institute for Biomedical Research, news release, Oct. 10, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ProVest Insurance ... greater Dallas, Miami, and Raleigh regions, is organizing an extended charity drive to ... and deadly chromosome abnormality. , After struggling since birth with several health challenges, ...
(Date:10/13/2017)... Ky. (PRWEB) , ... October 13, 2017 , ... The ... MPH to become its next President and Chief Executive Officer, succeeding Dr. James C. ... CEO Elect beginning July 1, 2018 until Dr. Puffer’s retirement at the end of ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of ... ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership in ... It also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 12, 2017 AVACEN Medical , Inc. (AVACEN) ... their  2017 New Product Innovation Award for Its fibromyalgia ... and secondary medical device market research by Frost & Sullivan,s ... OTC, drug-free pain relief product, the AVACEN 100, offers a ... fibromyalgia widespread pain. ...
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
Breaking Medicine Technology: