Navigation Links
Study Probes Difference Between Embryonic, Adult Stem Cells
Date:10/10/2007

Each develops in unique ways, researchers say

WEDNESDAY, Oct. 10 (HealthDay News) -- Adult stem cells lack a protein called Oct4, which helps maintain embryonic stem cells in an undifferentiated state, U.S. researchers report.

The findings suggest that the ability of stem cells to change into any kind of cell is regulated differently in adult and embryonic stem cells, the researchers said. The study also challenges findings from more than 50 studies that concluded that Oct4 was present in adult stem cells.

Using three independent detection methods to analyze six types of tissue in which Oct4-positive adult stem cells have been reported, the authors of the new study concluded that Oct4 was not present, or was present at only statistically insignificant levels, in these tissues.

The researchers at the Whitehead Institute for Biomedical Research in Cambridge, Mass., also found that Oct4 is not required to maintain mouse adult stem cells in their undifferentiated state and that adult tissues functioned normally when the Oct4 gene was deleted.

The study was published online Oct. 10 in the journal Cell Stem Cells.

Earlier studies may have misapplied analytical techniques or worked with cell cultures that had spent too much time in an incubator, said author Christopher Lengner, a postdoctoral fellow at the Whitehead Institute.

He and his team are now studying the mechanisms used by adult stem cells to change into any kind of cell.

"Is there a common pathway that governs stemness in adult stem cells, or does each stem cell have its own pathway? We don't know yet," Lengner said in a prepared statement.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Whitehead Institute for Biomedical Research, news release, Oct. 10, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... ... has struggled to quit smoking, a man who has struggled with hair loss – Craig ... problems – and he did. Now Nabat, a serial entrepreneur featured as the October 2015 ... the world and better people's lives. His own experience with nicotine addiction led to the ...
(Date:2/8/2016)... ... February 08, 2016 , ... Tingley ... into Canada to provide its range of unique and advantaged protective solutions ... City that will provide bilingual customer service and marketing support. A new distribution ...
(Date:2/8/2016)... ... February 08, 2016 , ... Local insurance agency Dennis Fuller ... area, has initiated a fundraiser for a two year old little girl named ... Christmas. To support this beautiful child who is facing life’s journey without her ...
(Date:2/8/2016)... ... February 08, 2016 , ... Remember the old saying ... , According to Perry A~, author of “Calcium Bentonite Clay” the health benefits of ... in balancing and detoxifying the body. , A former motivational speaker, Perry A~ has ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... Discover the ... visit over 1,400 booths and 700 companies. Attendees also get to see the ... Colorado Garden & Home Show , at the Colorado Convention Center - 700 ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... Feb.8, 2016 Alzheimer Diagnostic Tests - ... Medical Devices sector report , "Alzheimer Diagnostic ... an overview of Alzheimer Diagnostic Tests currently in ... on the pipeline products with comparative analysis of ... report reviews major players involved in the pipeline ...
(Date:2/8/2016)... Feb. 8, 2016 CBG Technologies, a ... Series Solvent Recycling Systems, specifically designed for precision ... with new and existing vapor degreasers, parts washers ... solvent through continuous recycling and recovers 100% of ... --> Precision parts manufacturers benefit ...
(Date:2/8/2016)... February 8, 2016 --> ... research report "Ablation Technologies Market by Product (Radiofrequency, Ultrasound, ... Management, Cosmetic Surgery, Ophthalmology, Gynecology) - Global Forecasts to ... market over the forecast period of 2015 to 2020. ... 2020, at CAGR of 10.5% from 2015 to 2020. ...
Breaking Medicine Technology: