Navigation Links
Study Points to Molecular Origins of Celiac Disease
Date:7/21/2010

By Melissa Lee Phillips
HealthDay Reporter

WEDNESDAY, July 21 (HealthDay News) -- Scientists believe they've identified the molecular triggers of celiac disease, a finding they say could lead to the first drugs to tame the chronic, painful gut disorder.

People with celiac disease are intolerant to the protein gluten, which is found in wheat, barley and rye. Consuming these foods triggers an immune reaction that damages the lining of the small intestine, which can prevent the body from absorbing essential vitamins and nutrients.

Currently, the only treatment for celiac disease is adoption of a gluten-free diet, which means avoiding many types of bread, pasta, cereal and other foods. But gluten contamination in many foods makes it difficult to avoid and leads to long-lasting intestinal damage in some patients, said study senior author Robert Anderson, head of the celiac disease research laboratory at the Walter and Eliza Hall Institute of Medical Research in Parkville, Australia.

Regulating the aberrant immune response to gluten with a drug "would be a much more efficient way of dealing with celiac disease," Anderson said, but an incomplete understanding of how the immune system responds to gluten has prevented researchers from developing such therapies.

Gluten actually consists of many different protein components, and it's been unclear which of these fragments induces the immune response seen in celiac disease.

"You can't design drugs for celiac disease until you know the parts of the gluten that are driving the condition," Anderson explained.

During their investigation, he and his colleagues analyzed immune responses in the blood of more than 200 celiac disease patients after they had consumed meals containing gluten.

The researchers screened the blood samples for responses to thousands of different protein fragments (peptides) found in gluten, and they found that the patients' immune
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. FDA Puts Partial Hold on Avandia Safety Study
2. Not Every ACL Tear Needs Early Surgery, Study Suggests
3. Most men in long-term study of HIV report low use of illicit drugs
4. Gladstone and Lundbeck collaborate to study neurovascular disease
5. New Study Finds HPV Vaccine Protects Against Genital Warts
6. Vaginal Gel Cuts Risk of HIV Infection, Study Shows
7. Research consortium at CHLA receives $410,000 to study leukemia and lymphoma
8. Concordia researcher leads study that finds kids reduce physical activity for heart patients
9. Study Suggests Higher Cancer Rate Among IVF Babies
10. HIV/AIDS treatment curbs spread of disease: UBC-BC CfE study
11. Anthony S. Fauci, M.D., on results from the CAPRISA 004 microbicide study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Points to Molecular Origins of Celiac Disease
(Date:5/20/2013)... News) -- A new Canadian study has uncovered an ... less likely than men to get trauma center care ... to health care services in general have been recognized ... disparities extend to the treatment of severe injuries in ... at Sunnybrook Health Sciences Centre and the University of ...
(Date:5/20/2013)... 2013 The International Distance Skateboard Association has ... for the best long distance skaters to attend and compete. ... a venue of raising money for our local Boys & ... IDSA is the authority on long distance races throughout the ... event is safe and organized for all who want to ...
(Date:5/20/2013)... 2013 CosmosID, a leading data mining solutions company for ... collaboration results on analysis of labeling claims for the ... , The Food and Drug Administration (FDA) and CosmosID ... probiotics, four of which have been reported at the ... tests was to compare the identity of species and ...
(Date:5/20/2013)... Dalton, Georgia (PRWEB) May 20, 2013 ... fields, has significantly expanded its presence in the Midwest ... office in Kansas City, Missouri. Sporturf Midwest is ... focus on Iowa, Nebraska, Missouri and Kansas. , ... Sporturf has not really been in before,” noted Shonk. ...
(Date:5/20/2013)... Online education provides the convenience, flexibility ... not offer. According to the American Heart Association, ... classroom learning to eLearning due to changing economic ... maximize training budgets, but it is also proven ... 25–60%. A higher retention of content is probable, ...
Breaking Medicine News(10 mins):Health News:Women Less Likely to Get Trauma Center Care After Injury: Study 2Health News:CosmosID unveils new tool for faster, specific and accurate testing of probiotics products 2Health News:Sporturf Expands into the Midwestern U.S. 2Health News:Swank HealthCare Announces New Offering of Additional American Heart Association’s Accredited Online Courses 2
... TORONTO, February 16, 2011 − One of the tough challenges ... how to parent the surviving children, and the task begins ... From the moment their child dies, parents are faced with ... loss of a child and the ongoing, daily demands from ...
... By Serena Gordon HealthDay Reporter , WEDNESDAY, ... Physicians has released new guidelines recommending that doctors not ... sugar levels in patients in medical or surgical intensive ... with diabetes and without the condition. The college recommends ...
... screening and treatment of genitourinary cancers were released today in ... February 17-19, 2011, at the Orlando World Center Marriott in ... in a media presscast (press briefing via live webcast): ... cancer death for men with low initial PSAs: A large ...
... with Alzheimer,s disease or other dementias, and their families, ... plan for the patient,s progressive loss of ability to ... physician at the San Francisco VA Medical Center and ... patient is diagnosed with Alzheimer,s disease or dementia, the ...
... Men with prostate cancer may be twice as likely to have ... 20 than those without prostate cancer, a new French study suggests. ... 40s do not appear to face a similar boost in prostate ... do not face a higher risk of developing the cancer at ...
... , TUESDAY, Feb. 15 (HealthDay News) -- A review of ... Americans pop at the first sign of a cold may, in ... conducted by a team in India and published in the ... people have to stay away from work or school. "This ...
Cached Medicine News:Health News:Parenting after the death of a child a difficult balancing act: York U study 2Health News:In-Hospital Blood Sugar Levels Should Be Higher: Report 2Health News:In-Hospital Blood Sugar Levels Should Be Higher: Report 3Health News:Research presented at 2011 GU Cancers Symposium highlights advances in treatment of prostate cancer 2Health News:Financial planning a key but neglected component of Alzheimer's care, say researchers 2Health News:Could Hair Loss at 20 Signal Higher Prostate Cancer Risk? 2Health News:Could Hair Loss at 20 Signal Higher Prostate Cancer Risk? 3Health News:Zinc May Help Ease Common Cold: Analysis 2
(Date:5/17/2013)... 17, 2013 Medical devices are any medical ... product. In light of their different mechanisms, actions and ... more complicated than drug trails due to their unique ... instead of evaluating both safety and efficacy (which is ... is the same as the SFDA) evaluate MDs for ...
(Date:5/17/2013)... DIEGO , May 17, 2013  Sorrento ... that its Fast-Track Advanced Technology Small Business Technology ... Institute of Allergy and Infectious Diseases (NIAID), a ... supporting the development of novel human antibody therapeutics ... aureus or Staph) infections, including methicillin-resistant ...
(Date:5/17/2013)... , May 17, 2013  Technology advances ... communicate internally. Faced with a constantly evolving communication ... and tactics for communicating with internal executives. It ... all the strategies, tactics and tools that are ... In a new study, Best Practices, LLC explores ...
Breaking Medicine Technology:Statistical Challenges in Medical Device Trail Evaluation 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 3Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 4Internal Communication Strategies and Tactics that Resonate with Key Stakeholders and Drive Organizational Effectiveness 2
... VANCOUVER, British Columbia, June 21, 2011 Enox Biopharma, Inc. ... East Investment in Innovation Conference on Wednesday, June 22 at ... Hyatt Regency Hotel in Boston. The IN3 ... and networking meeting. The meeting is designed to provide exposure ...
... Robbins & Myers, Inc. (NYSE: RBN ... approved its regular quarterly cash dividend payment of $0.045 ... 2011 to shareholders of record as of July 8, ... leading supplier of engineered equipment and systems for critical ...
Cached Medicine Technology:Enox Biopharma, Inc. Will Present at IN3 East Investment in Innovation Conference 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: