Navigation Links
Study Offers Clues to Why Some Don't Benefit From Asthma Drugs
Date:1/6/2012

By Kathleen Doheny
HealthDay Reporter

FRIDAY, Jan. 6 (HealthDay News) -- Almost half of patients with mild or moderate asthma may have a different type of disease than those with more severe symptoms, perhaps explaining why common treatments don't work well for them, new research suggests.

"We are beginning to understand that different 'flavors' of asthma probably have different molecular mechanisms," said Dr. John Fahy, director of the Airway Clinical Research Center at the University of California, San Francisco. He is the senior author of the new study, published online Friday in the American Journal of Respiratory and Critical Care Medicine.

Asthma is a chronic disease involving inflamed airways. As the airways become more swollen, the muscles around them can tighten when something triggers symptoms such as coughing, wheezing and shortness of breath.

Current anti-inflammatory treatments target a condition called eosinophilic airway inflammation, which is common in asthma. Eosinophils are a type of white blood cell that help fight off infection and play a role in the immune response.

However, the new research finds that nearly half of the 995 patients studied did not have this condition.

Fahy's team repeatedly measured these white blood cells in sputum samples of the volunteers with asthma who were enrolled in nine clinical trials.

Nearly half, or 47 percent, had no airway eosinophilia on any test of their sputum. Some had the condition intermittently and some had it on each test.

The investigators found that only 36 percent of those not taking an inhaled corticosteroid, an anti-inflammatory, had the condition, while 17 percent of those who used the inhaled steroids did.

After two weeks of giving the participants anti-inflammatories and bronchodilator therapy, Fahy found those with the airway eosinophilia responded and had better airflow. But those who didn't have the co
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Mice Exposed to Smoke Helped by Blood Pressure Drug: Study
2. Global Study Finds Drug Abuse Highest in Richer Nations
3. Diabetes Care Thwarted by Unstable Health Insurance: Study
4. Moderate red wine drinking may help cut womens breast cancer risk, Cedars-Sinai study shows
5. Mental Decline Can Start at 45, Study Finds
6. Study finds statin costs 400 percent higher in US compared to UK
7. Drug Eases Gout Flare-ups in Some Patients: Study
8. Study Reveals Whos More Prone to Be a Mean Drunk
9. Kaiser Permanente study finds continuous health coverage essential for patients managing diabetes
10. Safety-First Playgrounds Linked to Bored, Inactive Kids: Study
11. U-M study shows updated rotavirus vaccine not linked to increase in bowel obstruction
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Offers Clues to Why Some Don't Benefit From Asthma Drugs
(Date:4/18/2015)... More than 2000 styles of newly designed prom dresses ... store carrying celebrity inspired special occasion dresses. With the ... dresses for their prom. For those who are still ... would be an ideal choice. , "We have ... by the most loved styles seen at this years ...
(Date:4/18/2015)... “ ArcAngel ” was featured on NewsWatch as part of ... and coolest applications on the market for iOS, ... technology expert, conducted the app review and shared with viewers ... a turbulent world, people may find themselves in dangerous situations ... first move, but some situations can be avoided if there ...
(Date:4/17/2015)... Bradley, Illinois (PRWEB) April 18, 2015 ... community, will begin its Supportive Living Week Celebration on ... focus on having a healthy mind, body and soul. ... Marshall in McLeansboro, Illinois, serves older adults of all ... to maintain their independence. , Supportive Living Week is ...
(Date:4/17/2015)... ERGO-Pedic Products, LLC, which produces therapeutic memory foam ... help a broader range of people plagued by pain. ... most common visitors to doctors. , “The ERGO-Pedic Comfort ... relieve sitting pain. Then, only a couple months after ... later, we began getting questions from those customers, asking ...
(Date:4/17/2015)... Florida Hospital Wesley Chapel, Florida Hospital at Connerton ... all selected as Top Workplaces in Tampa Bay. ... ranked number one for large businesses according to the ... partnership with an independent research firm. Florida Hospital Wesley ... in October of 2012 with a vision of excellence ...
Breaking Medicine News(10 mins):Health News:Prom Dresses 2015 on Sale at TheCelebrityDresses.com 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Seat Cushion Company Credits Customer Driven Design For Two New Products 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4
... change how millions worldwide ... disease, DENVER, Oct. 21 Corgenix Medical Corporation,(OTC ... in Circulation confirm that elevated urinary levels of the,biomarker ... attack, stroke and cardiac death., The AspirinWorks(R) Test ...
... VANCOUVER, Oct. 21 /PRNewswire-FirstCall/ - CRH Medical ... few months it has trained,over 100 Gastroenterologists ... sell,the Company,s patented proprietary hemorrhoid banding technology ... approach complements,its core strategy of operating Centers ...
... Weight Watchers,International, Inc. (NYSE: WTW ) will ... NYSE close on Tuesday, November 4, 2008., The ... 4th at,5:00 p.m. ET. During the conference call, David ... Financial Officer, will,discuss third quarter results and answer questions ...
... score the title of Body By Milk MVP, ... fit has,become second nature to the superstar athletes at ... campaign announced today that the,Tigers Varsity football team has ... Players). The team was nominated to be part of ...
... 21 VIASPACE Inc. (OTC,Bulletin Board: VSPC) ... II contract for its proposal entitled "Miniature ... Aerial Vehicles (VTUAVs)" by the Navy,s,Small Business ... year contract will result in a field ...
... BOCA RATON, Fla., Oct. 21 The weight management ... the latest,addition to its Smart product line, the Smart ... a bagel on its head., The Smart Bagel ... the consumer full and satisfied for hours. Unique among,bagels, ...
Cached Medicine News:Health News:New CHARISMA Outcome Study Results Validate Aspirin Effect 2Health News:New CHARISMA Outcome Study Results Validate Aspirin Effect 3Health News:New CHARISMA Outcome Study Results Validate Aspirin Effect 4Health News:CRH Medical Corporation reaches milestone in partnership program 2Health News:CRH Medical Corporation reaches milestone in partnership program 3Health News:Weight Watchers Announces Third Quarter 2008 Earnings Conference Call 2Health News:North Carolina School Wins National got milk?(R) Refuel Your School Contest 2Health News:North Carolina School Wins National got milk?(R) Refuel Your School Contest 3Health News:VIASPACE Subsidiary Wins $786,000 U.S. Navy Contract 2Health News:Smart for Life(TM) Announces the New and Improved Bagel 2
(Date:4/16/2015)... , April 16, 2015 Mallinckrodt plc ... company, today announced that it has completed its ... of approximately $2.3 billion. The Ikaria acquisition extends ... its reach into neonatal critical care with INOMAX ... option for a highly vulnerable patient population. It ...
(Date:4/16/2015)... FLINT, Mich. , April 16, 2015  Diplomat ... of Shannon Beltrand to their senior leadership ... Beltrand will be responsible for securing and properly monitoring ... is secure both internally and externally. Additionally, she will ... planning. "We are very excited to ...
(Date:4/16/2015)... -- An IAVI -led team of scientists has ... major HIV subtypes A, B and C, with scalable ... vaccine candidates designed to elicit broadly neutralizing antibodies. The ... HIV for such antibodies. The new ... says Rich Wyatt , senior director, viral immunology, ...
Breaking Medicine Technology:Mallinckrodt Completes Acquisition Of Ikaria 2Mallinckrodt Completes Acquisition Of Ikaria 3Mallinckrodt Completes Acquisition Of Ikaria 4Mallinckrodt Completes Acquisition Of Ikaria 5Diplomat Names Shannon M. Beltrand as New CISO 2New Method Holds Promise for HIV Vaccine Development 2
... Inc. (NYSE: CRY ), a leading ... surgery, announced today that it has completed its ... and markets the HeRO (Hemodialysis Reliable Outflow) Graft, ... (ESRD) hemodialysis patients with limited access options and ...
... UBM Conferences , a division of UBM Plc (LSE: ... and Leachables Webinar to be hosted on May 17th, ... attend webinar will evaluate the considerations to be made ... in addition to highlighting how monomers and additives, such ...
Cached Medicine Technology:CryoLife Completes Acquisition of Hemosphere 2CryoLife Completes Acquisition of Hemosphere 3CryoLife Completes Acquisition of Hemosphere 4Global Webinar Focuses on Considerations for Extractables and Leachables 2
... multi-purpose topical gel contains 10% Povidone Iodine ... action. As a pre-operative prep, Povidone Iodine ... prepping solutions under the patient, thus reducing ... is also approved as a one step ...
... Iodine Prep Solution is appropriate for ... wet soak or spray); disinfecting of ... treatment of lacerations and abrasions. It ... agent in hospital and office procedures, ...
... Aplicare's Prep-Swab Ampule is ... a plastic tube that is ... has an absorbent applicator at ... tube is squeezed to break ...
... can be a valuable tool in standardizing ... items necessary for a procedure are supplied ... continuum of care are easier to be ... sequence of use, allowing the clinician to ...
Medicine Products: