Navigation Links
Study Links MS to Brain Chemical Deficiency
Date:2/15/2011

TUESDAY, Feb. 15 (HealthDay News) -- Multiple sclerosis is associated with reduced levels of an important neurotransmitter, noradrenaline -- a shortage caused by damage to an area of the brain called the locus coeruleus (LC), researchers have found.

Neurons in this part of the brain are a major source of noradrenaline, which plays an important role as an immunosuppressant in the brain, preventing inflammation and stress to neurons.

"There's a lot of evidence of damage to the LC in Alzheimer's and Parkinson's disease, but this is the first time that it has been demonstrated that there is stress involved to the neurons of the LC of MS patients, and that there is a reduction in brain noradrenaline levels," the study's first author, Paul Polak, a research specialist at the University of Illinois at Chicago, said in a university news release.

He and his colleagues found LC damage and reduced levels of noradrenaline in mice with MS and detected similar problems in the brains of people with the disease. The results suggest that LC damage and an accompanying reduction in noradrenaline levels may be common to many neurological diseases, they said.

The study was published online Feb. 4 in Brain.

"There are a number of FDA-approved drugs that have been shown to raise levels of noradrenaline in the brain, and we believe that this type of therapeutic intervention could benefit patients with MS and other neurodegenerative diseases, and should be investigated," Polak said.

More information

The American Academy of Family Physicians has more about multiple sclerosis.

-- Robert Preidt

SOURCE: University of Illinois at Chicago, news release, Feb. 11, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Kids Learn to Work Together Early, Study Finds
2. Study compares balanced propofol sedation with conventional sedation for therapeutic GI endoscopic procedures
3. Boston Medical Center critical care chief receives grant for lung injury study
4. Obesity Alone Raises Risk of Fatal Heart Attack, Study Finds
5. New study finds no cognitive impairment among ecstasy users
6. Obesity, Bum Knees Robbing Seniors of Good Years: Study
7. Playing Hard to Get May Get the Girl, Study Finds
8. Study Suggests Hearing Loss-Dementia Link
9. Energy Drinks May Hurt Kids: Study
10. Grant to study how to stop fumbled handoffs which can lead to medical errors
11. NIH study finds 2 pesticides associated with Parkinsons disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Links MS to Brain Chemical Deficiency
(Date:2/5/2016)... ... February 05, 2016 , ... Stuart Bentkover, MD, FACS ... Designed to provide the most effective tattoo removal today, Dr. Bentkover is the only ... Developed by Cynosure, the PicoSure has been approved by the Food and Drug Administration ...
(Date:2/5/2016)... ... 05, 2016 , ... Colorize is a web theme package created ... next using Colorize's dynamic moving camera. Colorize is perfect for personal and web related ... environment with 1 to 5 focus points per scene, stage floor scene presets that ...
(Date:2/5/2016)... ... ... Health and wellness is a topic that should concern all Americans; however, ... an illness. Migraines are a severe form of a headache and often are accompanied ... the pain on their worst enemy, the feeling can last for many hours and ...
(Date:2/5/2016)... Ramsey, NJ (PRWEB) , ... February 05, 2016 ... ... Optimizing Primary Care for Patients with Rare Diseases, a continuing medical education (CME) ... conference is the first of its kind—and a first for ACCORD, whose mission ...
(Date:2/5/2016)... ... February 05, 2016 , ... KICVentures ( http://www.kicventures.com ) announced ... in New York City on Thursday, January 21, 2016. Kingsley R. Chin, ... alumnus of the varsity Columbia soccer program) spoke at the event, offering professional ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)...  The Senior Care Pharmacy Coalition (SCPC) today ... Jason Chaffetz (R-UT) and Ranking Member ... , "Developments in the Prescription Drug Market," to ... about abusive pharmacy benefit manager (PBM) pricing practices. ... Member Elijah Cummings (D-MD) are diligent, serious lawmakers ...
(Date:2/4/2016)... , Feb. 4, 2016  Montoya Love is ... in the field of Pharmaceuticals. Montoya is the Regulatory ... Manufacturing and ... Becton Dickinson provides healthcare institutions, clinical laboratories ... throughout fifty countries across the globe. ...
(Date:2/4/2016)... Mettler-Toledo International Inc. (NYSE: MTD ) today announced ... highlights: , Sales in local currency increased ... Reported sales decreased 3% as currency reduced sales growth ... per diluted share as reported (EPS) were $4.44, compared ... was $4.65, an increase of 10% over the prior-year ...
Breaking Medicine Technology: