Navigation Links
Study Links MS to Brain Chemical Deficiency
Date:2/15/2011

TUESDAY, Feb. 15 (HealthDay News) -- Multiple sclerosis is associated with reduced levels of an important neurotransmitter, noradrenaline -- a shortage caused by damage to an area of the brain called the locus coeruleus (LC), researchers have found.

Neurons in this part of the brain are a major source of noradrenaline, which plays an important role as an immunosuppressant in the brain, preventing inflammation and stress to neurons.

"There's a lot of evidence of damage to the LC in Alzheimer's and Parkinson's disease, but this is the first time that it has been demonstrated that there is stress involved to the neurons of the LC of MS patients, and that there is a reduction in brain noradrenaline levels," the study's first author, Paul Polak, a research specialist at the University of Illinois at Chicago, said in a university news release.

He and his colleagues found LC damage and reduced levels of noradrenaline in mice with MS and detected similar problems in the brains of people with the disease. The results suggest that LC damage and an accompanying reduction in noradrenaline levels may be common to many neurological diseases, they said.

The study was published online Feb. 4 in Brain.

"There are a number of FDA-approved drugs that have been shown to raise levels of noradrenaline in the brain, and we believe that this type of therapeutic intervention could benefit patients with MS and other neurodegenerative diseases, and should be investigated," Polak said.

More information

The American Academy of Family Physicians has more about multiple sclerosis.

-- Robert Preidt

SOURCE: University of Illinois at Chicago, news release, Feb. 11, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Kids Learn to Work Together Early, Study Finds
2. Study compares balanced propofol sedation with conventional sedation for therapeutic GI endoscopic procedures
3. Boston Medical Center critical care chief receives grant for lung injury study
4. Obesity Alone Raises Risk of Fatal Heart Attack, Study Finds
5. New study finds no cognitive impairment among ecstasy users
6. Obesity, Bum Knees Robbing Seniors of Good Years: Study
7. Playing Hard to Get May Get the Girl, Study Finds
8. Study Suggests Hearing Loss-Dementia Link
9. Energy Drinks May Hurt Kids: Study
10. Grant to study how to stop fumbled handoffs which can lead to medical errors
11. NIH study finds 2 pesticides associated with Parkinsons disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Links MS to Brain Chemical Deficiency
(Date:12/2/2016)... ... ... Rijuven Corp launches rejiva ( http://www.rejiva.com ), a unique wearable technology that measures ... on the market can deliver all that rejiva can. , “Rejiva promotes relaxation and ... than the usual heart rate and steps taken”, adds Evens Augustin, CEO of Rijuven. ...
(Date:12/2/2016)... ... December 02, 2016 , ... "Pro3rd Accents Volume 2 is a ... versatile lower third titles with just a few clicks of the mouse," said Christina ... 30 lower third animations. Choose from various styles with accented animations, rigid boxes, simplistic ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... needy individuals and families from eight different sites throughout Miami-Dade and Broward counties. ... 1,000 volunteers worked very hard on Thanksgiving morning by putting together individual meals ...
(Date:12/2/2016)... ... December 02, 2016 , ... Date aired: ... of Type 2 Diabetes: The Owner’s Manual, http://realtimepressrelease.com/press-releases-tagged-with/daryl-wein , Sharon ... of Water, Global Climate Change and Your Health radio program syndicated on Voice ...
(Date:11/30/2016)... ... November 30, 2016 , ... ... that we have been designated as a Cigna Infertility Center of Excellence. The ... performance standards. , “It’s an honor to be designated a Cigna Infertility ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2, 2016  The Addiction Treatment Advisory Group ... Managed Care Pharmacy (AMCP), has released detailed findings ... the opioid addiction crisis, including through improved access ... ATAG,s newly released paper, "The Role of ... addresses many issues around gaps and barriers to ...
(Date:12/2/2016)... 2, 2016 Boston Scientific Corporation (NYSE: ... acquire certain manufacturing assets and capabilities of the Neovasc, ... biological tissue business, as well as a 15% equity ... in cash. The Neovasc advanced biological tissue business makes ... Scientific Lotus™ Valve System. * Upon completion of ...
(Date:12/2/2016)... On Thursday, the NASDAQ Composite ended ... Industrial Average edged 0.36% higher, to finish at 19,191.93; and ... broad based as six out of nine sectors ended the ... the following Services equities: Myriad Genetics Inc. (NASDAQ: ... Research Holdings Inc. (NASDAQ: INCR ), and La ...
Breaking Medicine Technology: