Navigation Links
Study Links MS to Brain Chemical Deficiency
Date:2/15/2011

TUESDAY, Feb. 15 (HealthDay News) -- Multiple sclerosis is associated with reduced levels of an important neurotransmitter, noradrenaline -- a shortage caused by damage to an area of the brain called the locus coeruleus (LC), researchers have found.

Neurons in this part of the brain are a major source of noradrenaline, which plays an important role as an immunosuppressant in the brain, preventing inflammation and stress to neurons.

"There's a lot of evidence of damage to the LC in Alzheimer's and Parkinson's disease, but this is the first time that it has been demonstrated that there is stress involved to the neurons of the LC of MS patients, and that there is a reduction in brain noradrenaline levels," the study's first author, Paul Polak, a research specialist at the University of Illinois at Chicago, said in a university news release.

He and his colleagues found LC damage and reduced levels of noradrenaline in mice with MS and detected similar problems in the brains of people with the disease. The results suggest that LC damage and an accompanying reduction in noradrenaline levels may be common to many neurological diseases, they said.

The study was published online Feb. 4 in Brain.

"There are a number of FDA-approved drugs that have been shown to raise levels of noradrenaline in the brain, and we believe that this type of therapeutic intervention could benefit patients with MS and other neurodegenerative diseases, and should be investigated," Polak said.

More information

The American Academy of Family Physicians has more about multiple sclerosis.

-- Robert Preidt

SOURCE: University of Illinois at Chicago, news release, Feb. 11, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Kids Learn to Work Together Early, Study Finds
2. Study compares balanced propofol sedation with conventional sedation for therapeutic GI endoscopic procedures
3. Boston Medical Center critical care chief receives grant for lung injury study
4. Obesity Alone Raises Risk of Fatal Heart Attack, Study Finds
5. New study finds no cognitive impairment among ecstasy users
6. Obesity, Bum Knees Robbing Seniors of Good Years: Study
7. Playing Hard to Get May Get the Girl, Study Finds
8. Study Suggests Hearing Loss-Dementia Link
9. Energy Drinks May Hurt Kids: Study
10. Grant to study how to stop fumbled handoffs which can lead to medical errors
11. NIH study finds 2 pesticides associated with Parkinsons disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Links MS to Brain Chemical Deficiency
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released a ... books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture of ... have tossed it off as mere rubbish, but Yisrayl Hawkins says that is because ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... Francisco, CA (PRWEB) , ... October 12, 2017 ... ... Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent ... apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... IsoComforter, Inc. ... products, announced today the introduction of an innovative new design of the shoulder pad. ... so you get maximum comfort while controlling your pain while using cold therapy. By ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... drug delivery system that we intend to develop to enable prevention of a ... lead to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... -- AVACEN Medical , Inc. (AVACEN) announced that Frost ... Product Innovation Award for Its fibromyalgia pain management device. ... device market research by Frost & Sullivan,s industry experts. ... relief product, the AVACEN 100, offers a safe and effective ... ...
(Date:10/11/2017)... Texas , Oct. 11, 2017  True ... services, has amplified its effort during National Breast ... about hereditary cancer risks. ... of Clinical Oncology calculated that more than 10 ... have inherited mutations in BRCA1 or BRCA2 and have ...
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
Breaking Medicine Technology: