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Study Links Brain Molecule to Risk of Major Depression
Date:2/8/2011

ickey, an assistant professor of psychiatry at the University of Michigan Medical School.

Researchers then injected participants' jaw muscles with a saline solution that causes brief moderate pain. The level of pain was adjusted for each person until they rated it a 4 on a 10-point scale.

Participants were asked to describe how they felt before and after the injection. Participants in the low NPY group reported more negative emotions both before and after the injection, suggesting they were more emotionally affected while both anticipating and thinking about the painful experience later.

The finding may eventually help with early diagnosis and treatment for depression, including individualized therapies based on a patient's genetic profile, the researchers said.

More information

The U.S. National Institute of Mental Health has more about depression.

-- Robert Preidt

SOURCE: University of Michigan Health System, news release, Feb. 7, 2011


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