Navigation Links
Study Links 'Body Clock' to Sudden Cardiac Death
Date:2/23/2012

THURSDAY, Feb. 23 (HealthDay News) -- The first molecular evidence linking circadian rhythms -- the "body clock" -- to sudden cardiac death could lead to new methods of diagnosis and therapy to treat or prevent the fatal heart problem, a new study suggests.

Abnormal heart rhythms called ventricular arrhythmias are the most common cause of sudden cardiac death, which is the primary cause of death from heart disease. Experts have long noticed that ventricular arrhythmias occur most often in the morning waking hours, with a smaller peak in the evening hours.

Despite knowing about this increased risk in the morning and evening, scientists haven't been able to pinpoint the molecular basis for these daily patterns. This study in the March 1 issue of the journal Nature may provide new insight.

The researchers found that a genetic factor called Kruppel-like factor 15 (KLF15) connects the body's natural circadian rhythm to, and regulates, the heart's electrical activity.

Too little or too much KLF15 causes a loss or disruption in the heart's electrical cycle and greatly increases the risk of arrhythmias, according to the study. For example, patients with heart failure lack KLF15 while too much KLF15 causes electrocardiography changes such as those that occur in patients with a genetic heart rhythm disorder called Brugada syndrome.

The findings could reduce the number of cases of sudden cardiac death. For example, medications that increase KLF15 could be given to heart failure patients, particularly during the times of day when sudden cardiac death is more likely to occur.

"Our study identifies a hitherto unknown mechanism for electrical instability in the heart. It provides insights into day and night variation in arrhythmia susceptibility that has been known for many years," study author Dr. Darwin Jeyaraj, an assistant professor of medicine at Case Western Reserve University School of Medicine and a car
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. New study shows promise for analyzing bladder pain syndrome
2. Medicare and Medicaid CT scan measure is unreliable according to new BWH study
3. Mammograms Can Save Lives of Women in Their 40s: Study
4. Study finds some insulin production in long-term Type 1 diabetes
5. Stronger intestinal barrier may prevent cancer in the rest of the body, new study suggests
6. Aspirin as Good as Plavix for Poor Leg Circulation: Study
7. Study: No Significant Rise in Seizure Risk From Common Kids Vaccine
8. Study: Brain makes call on which ear is used for cell phone
9. Cedars-Sinai awarded $2.5 million to study potential new drug treatments for Alzheimers disease
10. Worries About Colonoscopy Unfounded: Study
11. Perception, work-life balance key factors in workplace safety, says UGA study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Links 'Body Clock' to Sudden Cardiac Death
(Date:1/22/2015)... NY (PRWEB) January 22, 2015 ... of Sports Medicine flagship journal Medicine & Science ... L-Citrulline before exercise may help reduce gastrointestinal (GI) ... 1 , Participants in the double-blind, placebo-controlled ...
(Date:1/22/2015)... Recently, Weddingshe.com has added many trendy ... its highest annual revenues in the past three years. Today, ... wedding dresses. , According to the sales manager of the ... for them in 2015. This point can be reflected on ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Four years since the ... – which coincided with the marriage of Avasa & Matthew Love ... ROAD, which is scheduled for release through White Swan Records on ... that there is a sacred path available to all of us ...
(Date:1/22/2015)... IPSWICH, Mass. (PRWEB) January 22, 2015 ... Association (AMA) are expanding their relationship in an effort ... journals around the world. While EBSCO has long made AMA ... as a sales agent for The JAMA Network. ...
(Date:1/22/2015)... January 22, 2015 JJsHouse.com is a famous ... Today, the business announces its latest collection of wedding ... “The most important issue is the wedding dress on your ... in a woman’s life. Every bride wants to find the ...
Breaking Medicine News(10 mins):Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... vaccine, which is under experiment, or even leaving it to die, or ... attacks America. ,About making tricky decisions, changes in conclusions ... in a new study. ... findings may help individuals who face tough health choices, and decision-makers who ...
... the air at Shilpa's stall at the 'Aravanis' talent village' ... for his marriage with hundreds of transvestites in an annual ... among nearly 300,000 transvestites who live in this South Indian ... They say transvestites are good cooks because mythological hero Arjuna ...
... of HIV/AIDS is declining in the western Indian state of ... Karnataka and Andhra Pradesh because of the proactive measures taken ... the country, especially in the north, it is rising, a ... Tuesday, said that overall two-thirds of the people living with ...
... of treatment. But to a benefit of all GPs in Scotland ... ,A resident artist much like resident doctors has been appointed at ... a graduate of the Edinburgh School of Art. ,A whooping ... ,It is one of 27 projects across Scotland awarded a ...
... to the recent outbreak of E-coli 0157, which is a ... with a lethal and even fatal food poisoning infection//. Three ... traced to a slaughtering outlet in South Lanarkshire, were confirmed ... to inform the public about its dangers. But this by ...
... study published contradicts the previous research that showed that ... The latest Study shows that a high fat intake ... non-melanoma skin cancer. ,Robert Granger and colleagues from ... from Murdoch Children's Research Institute in Melbourne studied 652 ...
Cached Medicine News:Health News:Insight Into The Risky Health Decisions On Bird Flu 2Health News:Insight Into The Risky Health Decisions On Bird Flu 3Health News:Insight Into The Risky Health Decisions On Bird Flu 4Health News:Drawing from Myth to Become Mistress of Spices 2Health News:Drawing from Myth to Become Mistress of Spices 3
(Date:1/22/2015)...  Bio-Techne Corporation (NASDAQ: TECH ) announced today ... the new Simple Plex platform through its Proteins Platform ... re-branding of the previously acquired CyPlex instrument platform from ... transformative immunoassay technology which integrates an innovatively designed microfluidic ...
(Date:1/22/2015)... DUBLIN , Jan. 22, 2015 Research and Markets ... of the "Infectious Disease Diagnostics Market by Product, ... report to their offering. , The ... CAGR of 7.9% to reach $18,156.2 million by 2019 ...
(Date:1/22/2015)... The Parenteral Drug Association (PDA) today announced the launch ... Pharmaceutical Manufacturing,s Future. The Manufacturing Science ... , Highlight the ongoing focus PDA has on pharmaceutical and ... filling known gaps in current manufacturing science as well as ...
Breaking Medicine Technology:Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 2Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 3PDA Launches Manufacturing Science Program(SM) 2PDA Launches Manufacturing Science Program(SM) 3
... MedImmune today announced,that it has initiated a Phase ... healthy children one month to 12 months of age ... is,the most common respiratory infection in infants and can ... is a serious respiratory disease that can have significant ...
... Meeting -, - Conference call to be hosted ... BRANFORD, Conn., Nov. 3 CuraGen Corporation,(Nasdaq: CRGN ... II,trial of CR011-vcMMAE, an antibody-drug conjugate that targets GPNMB, ... Stage IV melanoma.,Dr. Patrick Hwu, Co-Principal Investigator, and Professor ...
Cached Medicine Technology:MedImmune Advances Pediatric Disease Prevention Program With Start of Phase 1/2a Clinical Trial for Respiratory Syncytial Virus Vaccine 2CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma 2CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma 3CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma 4CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma 5CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma 6CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma 7
... images are transmitted through sorted ... picture and transmit it to ... flexoscopes are designed for rough, ... repaired at low cost if ...
Bipolar gingivoplasty loop. Individual sterile packs....
Electric high speed system....
The XK-PRO 100 High Speed Drill System is a compact, lightweight design that offers new technological and performance standards for a combination of surgical procedures....
Medicine Products: