Navigation Links
Study Links Blood Type and Pancreatic Cancer
Date:3/10/2009

Findings shed light on gene serving as marker for others involved in tumor development

TUESDAY, March 10 (HealthDay News) --- People with type O blood have a much lower risk of developing pancreatic cancer, a finding that might help explain the origins of the often fatal disease.

The study, by researchers at the Dana-Farber Cancer Institute in Boston, confirms a previously suggested tie between blood type and the disease, which is diagnosed in about 40,000 people each year in the United States.

The study found that the chances of developing pancreatic cancer were greater for people with a blood type other than O: 32 percent higher for those with type A blood, 51 percent greater for type AB and 72 percent higher for type B .

However, because only a little more than 1 percent of the general population is at risk for the disease, the researchers said that blood type would not serve as a helpful screening method in the future.

"Except for several rare familial syndromes, the genetic factors that raise or lower an individual's risk for pancreatic cancer are largely unknown," the study's lead author, Dr. Brian Wolpin, said in a news release from the cancer institute.

"The association between blood type and pancreatic cancer risk provides a new avenue for getting at the biological mechanisms that underlie the disease," he said. "Understanding the biology will put us in a better position to intervene so the cancer doesn't develop or progress."

Glycoproteins, compounds of sugar and protein found on the surface of red blood cells and other cells, including those in the pancreas, help define the four major blood types. A gene called ABO helps put these glycoproteins together by arranging sugar molecules on a protein "backbone" called the H antigen. In people with type O blood, the antigen has no sugars attached to it.

Previous studies have found that normal pancreas cells have blood-type antigen patterns that differ from those in pancreatic tumor cells, leading to speculation that the ABO gene might have a role in determining whether cells become cancerous.

The authors, whose study was published online in the Journal of the National Cancer Institute, wrote that their findings do not necessarily prove a direct link between blood-type antigens and pancreatic cancer development, but they may show that the ABO gene serves as a marker for other genes more directly involved in cancer development.

More information

The American Cancer Society has more about pancreatic cancer.

SOURCE: Dana-Farber Cancer Institute, news release, March 10, 2009



-- Kevin McKeever



SOURCE: Dana-Farber Cancer Institute, news release, March 10, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New study identifies risk factors in severity of flat head syndrome in babies
2. New Study Shows That One-Third of Shelter Youth Have Been Institutionalized; Almost One-Half Suffered Violence in the Home
3. Beaumont Launches 1st U.S. Adult Human Stem Cell Study for Stress Urinary Incontinence
4. Common Approaches to Member Retention by Health Insurance Plans are Ineffective, New Study Shows
5. Celator(R) Pharmaceuticals Enrolls First Patient in Its Phase 2 Study of CPX-351 in Acute Myeloid Leukemia in First Relapse
6. Study Shows 80% of Adults with Peripheral Arterial Disease Go Undiagnosed
7. Study finds pay for performance stimulates changes in medical practice
8. Study: Doctor-patient conversations at end of life associated with lower medical expenses
9. Study tests reliability of more accurate measure of patient pain
10. New published study demonstrates over-the-counter device lowers blood pressure in diabetic patients
11. Study prompts new mandate for N.C. high schools
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Links Blood Type and Pancreatic Cancer
(Date:6/23/2017)... VA (PRWEB) , ... June 23, 2017 , ... ... of what is needed and will ultimately do significant harm to people with ... to everyone. , "While it leaves in place the Affordable Care Act ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... plastic surgeon practicing in Newburgh, New York, has recently begun offering three new ... to offering the best cutting-edge procedures and reducing downtime, Dr. Rubinstein is excited ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... cooking is essential, and two new videos highlight the importance of correctly using ... Christine Bruhn, Ph.D., who has done extensive research on consumer food safety habits. ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ross Insurance ... With the Federal Emergency Management Agency’s (FEMA) recent update of flood zones, more ... 2012, the Biggert-Waters Act was enacted to reflect the actual risk in flood ...
(Date:6/23/2017)... ... June 23, 2017 , ... All-Star Insurance, a family managed agency that offers ... Texas, is announcing the launch of a new charity drive to benefit women in ... United States reveal that an estimated 252, 710 new cases of invasive or high ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... 1, 2017 Nutriceutical Holdings (NH), parent company ... (VRS), and KD Pharma Group have decided to join ... KD Pharma Group. KD Pharma Group will become the ... acquire the entire company. "We believe we ... committed to growing the NH companies by providing us ...
(Date:5/26/2017)... 26, 2017  Endo International plc (NASDAQ: ENDP ... CEO, will represent the Company in a fireside chat at ... Tuesday, June 13, 2017 at 10:40 a.m. PT / 1:40 ... in Rancho Palos Verdes, CA. ... will be available on the Company,s website at http://www.endo.com/investors/overview ...
(Date:5/22/2017)...  As the specialty pharmacy industry and the ... the revolutionary shift from volume-based to value-based care, ... patient outcomes and shaping the future of the ... from clinical trials and toward data that reveals ... therapy utilization in precise patient populations. Therigy ® ...
Breaking Medicine Technology: