Navigation Links
Study Links Blood Type and Pancreatic Cancer
Date:3/10/2009

Findings shed light on gene serving as marker for others involved in tumor development

TUESDAY, March 10 (HealthDay News) --- People with type O blood have a much lower risk of developing pancreatic cancer, a finding that might help explain the origins of the often fatal disease.

The study, by researchers at the Dana-Farber Cancer Institute in Boston, confirms a previously suggested tie between blood type and the disease, which is diagnosed in about 40,000 people each year in the United States.

The study found that the chances of developing pancreatic cancer were greater for people with a blood type other than O: 32 percent higher for those with type A blood, 51 percent greater for type AB and 72 percent higher for type B .

However, because only a little more than 1 percent of the general population is at risk for the disease, the researchers said that blood type would not serve as a helpful screening method in the future.

"Except for several rare familial syndromes, the genetic factors that raise or lower an individual's risk for pancreatic cancer are largely unknown," the study's lead author, Dr. Brian Wolpin, said in a news release from the cancer institute.

"The association between blood type and pancreatic cancer risk provides a new avenue for getting at the biological mechanisms that underlie the disease," he said. "Understanding the biology will put us in a better position to intervene so the cancer doesn't develop or progress."

Glycoproteins, compounds of sugar and protein found on the surface of red blood cells and other cells, including those in the pancreas, help define the four major blood types. A gene called ABO helps put these glycoproteins together by arranging sugar molecules on a protein "backbone" called the H antigen. In people with type O blood, the antigen has no sugars attached to it.

Previous studies have found that normal pancreas cells have blood-type antigen patterns that differ from those in pancreatic tumor cells, leading to speculation that the ABO gene might have a role in determining whether cells become cancerous.

The authors, whose study was published online in the Journal of the National Cancer Institute, wrote that their findings do not necessarily prove a direct link between blood-type antigens and pancreatic cancer development, but they may show that the ABO gene serves as a marker for other genes more directly involved in cancer development.

More information

The American Cancer Society has more about pancreatic cancer.

SOURCE: Dana-Farber Cancer Institute, news release, March 10, 2009



-- Kevin McKeever



SOURCE: Dana-Farber Cancer Institute, news release, March 10, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New study identifies risk factors in severity of flat head syndrome in babies
2. New Study Shows That One-Third of Shelter Youth Have Been Institutionalized; Almost One-Half Suffered Violence in the Home
3. Beaumont Launches 1st U.S. Adult Human Stem Cell Study for Stress Urinary Incontinence
4. Common Approaches to Member Retention by Health Insurance Plans are Ineffective, New Study Shows
5. Celator(R) Pharmaceuticals Enrolls First Patient in Its Phase 2 Study of CPX-351 in Acute Myeloid Leukemia in First Relapse
6. Study Shows 80% of Adults with Peripheral Arterial Disease Go Undiagnosed
7. Study finds pay for performance stimulates changes in medical practice
8. Study: Doctor-patient conversations at end of life associated with lower medical expenses
9. Study tests reliability of more accurate measure of patient pain
10. New published study demonstrates over-the-counter device lowers blood pressure in diabetic patients
11. Study prompts new mandate for N.C. high schools
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Study Links Blood Type and Pancreatic Cancer
(Date:10/13/2017)... Rock, AR (PRWEB) , ... October 13, 2017 ... ... firm with locations throughout Arkansas that offers insurance and financial preparation services, is ... benefit the Rock City Rescue organization. , Rock City Rescue is a locally ...
(Date:10/13/2017)... , ... October 13, 2017 , ... PurhealthRX , ... Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize ... providing a CBD form that can be easily incorporated into liquid products, while reducing ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... The Visiting ... Day Market. Featuring a collection of specialty vendors and unique items from across the ... and quality-focused health and wellness services offered by the VNA. The boutique will ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of ... announced today its plans to open a flagship location in Covington, LA at 401 ... Rooms To Go store next to Office Depot in the Holiday Square shopping center. ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will host ... webcast on Friday, November 3, 2017, beginning at 7:00 ... approximately 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... performance and guidance for 2018, Hill-Rom executives will also ... performance, and long-range financial outlook through 2020. ...
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. ... big data solutions, today announced that its MyDario product is expected to ... TV listings for when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, ... ...
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
Breaking Medicine Technology: