Navigation Links
Study IDs benefit of donor SCT for adults with acute myeloid leukemia
Date:6/9/2009

BOSTON--A stem cell transplant (SCT) from a compatible donor early in the course of disease is the best approach for the majority of young and middle-aged adult patients with acute myeloid leukemia (AML), according to a new analysis of two dozen clinical studies.

The findings of the study, published in the June 10 issue of the Journal of the American Medical Association by researchers at Dana-Farber Cancer Institute and other institutions, provide new guidelines for treatment of the disease. For all AML patients other than the minority with "good-risk" disease, SCT from a compatible donor significantly improves survival, making it the preferred approach, the authors state.

The customary treatment for AML involves an initial "induction" phase that uses a combination of chemotherapy agents to put the disease into a first remission. The second stage of treatment, called "consolidation," is undertaken with the goal to cure the disease. Consolidation options include additional rounds of chemotherapy; autologous transplantation (which uses a patient's own blood stem cells); or allogeneic SCT (in which compatible donor cells are transplanted).

Traditionally, the treatment offered to patients has largely been based on a chromosome analysis of their AML cells. For AML with "good-risk" chromosome changes, additional chemotherapy or an autologous transplant is usually recommended. For AML with "poor-risk" changes, allogeneic SCT is usually recommended. For AML with "intermediate-risk" changes (the largest group), there has been no consensus on the best treatment.

In the new study, researchers confirmed that, consistent with current practice, patients with poor-risk AML benefited significantly from an allogeneic transplant performed in first remission, while those with good-risk disease did not benefit from the procedure. For patients with intermediate-risk disease, who account for nearly half of all adult AML patients, allogen
'/>"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Jazz Pharmaceuticals to Present Data From First Phase III Study of Sodium Oxybate in Patients With Fibromyalgia
2. New study indicates radiologists need standards to ensure optimal visual accuracy
3. Medifocus, Inc. receives Authorization Approval from Health Canada to launch its pivotal Phase III clinical study of focused microwave heating for treatment of breast cancer in Canada
4. Results From Phase 1 Clinical Study of PEG-PAL in PKU and Update on Phase 2 Clinical Study
5. Hospital Infection Prevention Resources Cut, Study Says
6. More Ontario children are getting diagnosed with diabetes: ICES study
7. Brain Imaging Study Confirms Cognizin(R) Citicoline Boosts Mental Function; to be Presented at International Society of Sports Nutrition Annual Conference
8. Women underrepresented in cancer research, U-M study finds
9. Women under-represented in cancer research, U-M study finds
10. NEJM study points to new era in hepatitis C treatment
11. Avandia Attorney Says Study Based on Useless Trick Science
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... ... the industry. , Worldwide Power Products is expanding its reach in Texas. Effective ... the Alpine Power Systems North Texas generator division. With the North Texas ...
(Date:8/4/2015)... ... August 04, 2015 , ... ... Food,” scheduled for Nov. 3 – 4, 2015, at UC San Diego, will ... new businesses, improve food access, and manage resources efficiently against the dueling backdrop ...
(Date:8/4/2015)... VEGAS, Nevada (PRWEB) , ... August 04, 2015 , ... ... of radio interviews to discuss his new book, The Pain Antidote , which ... Medical Director of Las Vegas Recovery Center’s Chronic Pain Treatment Program, wrote the book ...
(Date:8/4/2015)... ... 04, 2015 , ... Members receiving care from a doctor who participates in ... that is nine percent lower -- than those members at traditional doctor practices, according ... programs. , “The promise of patient-centered, or value-based, care to deliver better quality ...
(Date:8/4/2015)... , ... August 04, 2015 , ... They say a ... understand certain health conditions, pictures and medical art can be essential. StayWell, a health ... , Krames Patient Education solutions have been used by physicians and other health ...
Breaking Medicine News(10 mins):Health News:North Texas Acquisition Press Release 2Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 2Health News:Diversity of Urban and Hydroponic Farms of the Future to Highlight Seedstock Annual Conference Field Trip 3Health News:Medical Expert's New Book Offers Help for Chronic Pain Sufferers 2Health News:Medical Expert's New Book Offers Help for Chronic Pain Sufferers 3Health News:Horizon BCBSNJ: 2014 Results Show Patient-Centered Care Continues to Deliver on Promise of Better Quality Care at a Lower Cost 2Health News:Horizon BCBSNJ: 2014 Results Show Patient-Centered Care Continues to Deliver on Promise of Better Quality Care at a Lower Cost 3Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 2Health News:StayWell Offers Instant Downloads, Licensing of Medical Art to Improve Patient Education 3
... the oldest branch of the human immune system have ... both involving a central component of an enzyme important ... how this system fights invading microbes while avoiding problems ... pave the way to more efficient therapeutics for such ...
... TCT (Transcatheter Cardiovascular Therapeutics) 2009, the scientific symposium ... medical forum of updates and clinical trial data in ... cardiology. Media may now register to attend TCT ... September 21-25, 2009 Late-breaking clinical trials and ...
... ... panel discussing strategic measurement during a seminar co-sponsored by the American Association of Port ... June 23-25 in Detroit. , ... Livingston, NJ (PRWEB) June 17, 2009-- BurrellesLuce Vice President Johna ...
... ... ) announced today that IDG,s Computerworld has selected them as one ... Places to Work in IT is an annual list released by ... Medical, through a national network, offers produts and services to the ...
... method for scanning breast tissue may help find what traditional ... , , Listen to this report from Siemens (NYSE: ... , , Registered journalists can access video, ... at http://www.mediaseed.tv . , ...
... Brings Awareness Across Country; , Partnership with Depend Helps Raise ... Zero prostate cancer deaths. Zero prostate cancer cases and for those ... it all -- zero tolerance for prostate cancer. , ... is pleased to announce its partnership with Kimberly-Clark Corporation and the ...
Cached Medicine News:Health News:Structures from the human immune system's oldest branch shed light on a range of diseases 2Health News:Structures from the human immune system's oldest branch shed light on a range of diseases 3Health News:BurrellesLuce Executive to Speak on Measuring Communications Impact At Joint Seminar of Port-Industry Group and PRSA's Detroit Chapter 2Health News:BurrellesLuce Executive to Speak on Measuring Communications Impact At Joint Seminar of Port-Industry Group and PRSA's Detroit Chapter 3Health News:IDG's Computerworld Names Progressive Medical to Annual List of Best Places to Work in Information Technology 2Health News:IDG's Computerworld Names Progressive Medical to Annual List of Best Places to Work in Information Technology 3Health News:IDG's Computerworld Names Progressive Medical to Annual List of Best Places to Work in Information Technology 4Health News:Organization Announces End Prostate Cancer Tour 2Health News:Organization Announces End Prostate Cancer Tour 3
(Date:8/4/2015)... , Aug. 4, 2015 Governor Tom Wolf ... company that develops and markets implants in the spine and ... Hanover Township , Northampton County ... move that will create 25 new, full-time jobs. ... and create more than two dozen, high-paying jobs ...
(Date:8/4/2015)... Aug. 4, 2015  Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL ... and six months ended June 30, 2015. ... are progressing and we continue to expect results in ... president and chief executive officer of Rigel. "We are ... programs, including evaluating fostamatinib for new treatment indications, as ...
(Date:8/4/2015)... Calif., Aug. 4, 2015  Xencor, Inc. (NASDAQ: ... engineered monoclonal antibodies for the treatment of autoimmune ... reported financial results for the second quarter ended June ... business highlights. "Currently eight XmAb® antibody ... and two internal. The accelerating momentum of this ...
Breaking Medicine Technology:Wolf Administration Announces Tyber Medical to Establish Operations and Create New Jobs in Northampton County 2Wolf Administration Announces Tyber Medical to Establish Operations and Create New Jobs in Northampton County 3Rigel Announces Second Quarter 2015 Financial Results 2Rigel Announces Second Quarter 2015 Financial Results 3Rigel Announces Second Quarter 2015 Financial Results 4Rigel Announces Second Quarter 2015 Financial Results 5Rigel Announces Second Quarter 2015 Financial Results 6Xencor Reports Second Quarter 2015 Financial and Operating Results 2Xencor Reports Second Quarter 2015 Financial and Operating Results 3Xencor Reports Second Quarter 2015 Financial and Operating Results 4Xencor Reports Second Quarter 2015 Financial and Operating Results 5Xencor Reports Second Quarter 2015 Financial and Operating Results 6Xencor Reports Second Quarter 2015 Financial and Operating Results 7Xencor Reports Second Quarter 2015 Financial and Operating Results 8Xencor Reports Second Quarter 2015 Financial and Operating Results 9
... Cardinal Health today opened its first cyclotron facility ... capability to manufacture molecular imaging biomarkers that aid in ... disorders and heart disease. Cyclotrons are critical ... molecular imaging agents, one of the fastest-growing areas of ...
... 2011 Household relationships, gender preferences and population penetration aren,t ... as part of the Trojan® U.S. SEX CENSUS uncovers that ... and diverse as the population.  On a national level, the ... sex 120 times a year (2.3 times per week), and ...
Cached Medicine Technology:Cardinal Health Extends Radiopharmaceutical Manufacturing Network, Opening its First Cyclotron in Georgia 2Cardinal Health Extends Radiopharmaceutical Manufacturing Network, Opening its First Cyclotron in Georgia 3Trojan U.S. SEX CENSUS Finds Sexual Diversity and Satisfaction on Rise 2Trojan U.S. SEX CENSUS Finds Sexual Diversity and Satisfaction on Rise 3Trojan U.S. SEX CENSUS Finds Sexual Diversity and Satisfaction on Rise 4Trojan U.S. SEX CENSUS Finds Sexual Diversity and Satisfaction on Rise 5
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: