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Study Hints at Link Between Antidepressants and Heart Trouble
Date:4/3/2011

n the study, Dr. Dominique L. Musselman, an associate professor of clinical psychiatry at the University of Miami Miller School of Medicine, underscored that the findings show an association between antidepressant use and atherosclerosis, but not a cause-and-effect relationship.

"This finding is somewhat counterintuitive since it is well known that SSRIs enhance a tendency to bleed," she said, adding that more rigorous studies are needed to see if a cause-and-effect relationship exists.

Musselman also strongly advises patients not to stop taking antidepressants based on this study. Not treating depression can have serious consequences for quality of life, survival after a heart attack or other cardiovascular events, she said.

"This is an important finding that needs to be replicated," she added.

More information

For more on antidepressants, visit the U.S. National Library of Medicine.

SOURCES: Gregg C. Fonarow, M.D., professor, cardiology, University of California, Los Angeles; Dominique L. Musselman, M.D., associate professor of clinical psychiatry, University of Miami Miller School of Medicine; April 2, 2011, presentation, American College of Cardiology annual scientific session, New Orleans


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