Navigation Links
Study Finds Possible Explanation for the Link Between Infertility and Breast/Ovarian Cancer Risks
Date:12/11/2009

Westchester Medical Center Physician and Fertility Preservation Expert leads study examining the association of breast cancer genes, breast cancer and infertility

VALHALLA, N.Y., Dec. 11 /PRNewswire-USNewswire/ -- In a study published online this week in the leading cancer journal, Journal of Clinical Oncology, Westchester Medical Center Physician Dr. Kutluk Oktay, MD, Director, Division of Reproductive Medicine & Infertility concluded that mutations in the BRCA1 gene (gene associated with early onset breast cancer) are associated with early diminishment of egg reserve. This finding may, at least in part, explain the link between infertility and breast/ovarian cancer risks.

During the study, Dr. Oktay's team performed ovarian stimulation in 126 women with breast cancer for the purpose of fertility preservation by embryo or oocyte cryopreservation.

The results found that of the 82 women who met the inclusion criteria, 47 women (57%) had undergone BRCA testing, and 14 had a mutation in BRCA genes. In BRCA mutation-positive patients, low ovarian response rate was significantly higher compared with BRCA mutation-negative patients and with BRCA-untested women. All BRCA mutation-positive low responders had BRCA1 mutations, but low response was not encountered in women who were only BRCA2 mutation positive. Compared with controls, BRCA1 mutation -- but not BRCA2 mutation-positive women produced lower numbers of eggs.

It is estimated that, in the general population, one in every 1,000 women is BRCA mutation positive, and this incidence is as high as 2.5% in certain ethnic groups. Regardless of underlying mechanisms of early diminishment of egg reserve in BRCA1 mutation-positive women, the findings may have profound implications for the future fertility of a large number of women in the general population.


'/>"/>
SOURCE Westchester Medical Center
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... ... ... Google recently announced that it will be disclosing any incidents involving its ... 8, 2015 article published by Nasdaq , the powerful tech company maintains that ... cars, which such industry players as Tesla CEO Elon Musk believe may very well ...
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... ... its monthly Biz Report, which takes a look at small, medium, and large ... and a business expert, conducted the business review and shared with viewers how ...
(Date:7/30/2015)... ... July 30, 2015 , ... 24/7 Care At Home, a high-quality provider ... recently announced that the Centers for Medicare and Medicaid (CMS) have awarded its agency ... providers. 24/7 Care At Home’s agency is one of three top Orange County agencies ...
(Date:7/30/2015)... ... 2015 , ... The need for accessibility is never greater than when we ... as well as visiting friends and family during these critical moments, hospitals around the ... - powered by ChargeItSpot , a Philadelphia-based startup that recently secured a $4M ...
(Date:7/30/2015)... ... July 30, 2015 , ... ... as the company and UCLA’s Jonsson Comprehensive Cancer Center (JCCC) mutually ... With the new collaboration, OncLive’s editorial and marketing groups will help spread the ...
Breaking Medicine News(10 mins):Health News:New Google Policy on Reporting Driverless Auto Accidents Points Out Growing Complexity of Personal Injury Law in the 21st Century, Says Law Offices of Burg and Brock 2Health News:New Google Policy on Reporting Driverless Auto Accidents Points Out Growing Complexity of Personal Injury Law in the 21st Century, Says Law Offices of Burg and Brock 3Health News:Software to Develop High-Performance Data-Driven Apps was Featured on NewsWatch Television 2Health News:24/7 Care At Home Earns a 5-Star Rating from the Centers for Medicare and Medicaid (CMS) 2Health News:Hospitals Add Phone Charging Stations as an Amenity for Patients and Visitors 2Health News:UCLA Jonsson Comprehensive Cancer Center Teams with OncLive® as a Strategic Alliance Partner 2Health News:UCLA Jonsson Comprehensive Cancer Center Teams with OncLive® as a Strategic Alliance Partner 3Health News:UCLA Jonsson Comprehensive Cancer Center Teams with OncLive® as a Strategic Alliance Partner 4
... Elected 2008 President of the HBA, FAIRFIELD, ... at its,helm, Elizabeth M. Mutisya, MD, and a ... (HBA) continues to,mark its 30th Anniversary with an ... furthering the advancement of women leaders in,healthcare worldwide. ...
... should only,approve the proposed merger of Highmark and ... competition in,Pennsylvania, Capital BlueCross President and CEO Anita ... Smith was asked by Committee Chairman Sen. Don ... the lens of the uniquely competitive,health- insurance landscape ...
... Crowell & Moring LLP is,pleased to announce the ... office as a member of the firm,s Antitrust and ... she helped found and co-chair,the firm,s Healthcare Industry Group. ... Trade Commission (FTC), where she investigated and,prosecuted mergers, joint ...
... Prescription and ... Over-The-Counter Medications, LOS ANGELES, Jan. 30 ... aches, pains and debilitating,arthritis. Most often, pain sufferers reach for ... and how to treat it safely, effectively,and more holistically. In ...
... CAMBRIDGE, England, January 30 The next generation ... of IT and different,expectations regarding healthcare than their ... by Cambridge, UK-based Wireless Healthcare,will increase the take ... being used by the elderly., In the ...
... Michigan Chamber of,Commerce today released the following statement by ... the Michigan Chamber, in response to,Governor Granholm,s call in ... to make it easier for personal injury lawyers to ... stressed the need to work cooperatively,to move Michigan forward, ...
Cached Medicine News:Health News:Healthcare Businesswomen's Association Announces 2008 Board of Directors 2Health News:Healthcare Businesswomen's Association Announces 2008 Board of Directors 3Health News:Capital BlueCross CEO Says Meaningful Statewide Competition Must Be Key Criteria in Pennsylvania's Review of Proposed Highmark-IBC Merger 2Health News:Former FTC Attorney Christine White Joins Crowell & Moring's Health Care and Antitrust Groups 2Health News:Former FTC Attorney Christine White Joins Crowell & Moring's Health Care and Antitrust Groups 3Health News:Photos: Niavin Corporation Offers Pain Sufferers a New Way to Address Pain 2Health News:Increase in IT Skills Amongst the Elderly Will Boost Telecare Market 2
(Date:7/30/2015)... 30, 2015  Medimetriks Pharmaceuticals, Inc. announced today ... III clinical study for Ozenoxacin, a novel bactericidal ... the exclusive U.S. rights to Ozenoxacin 1% cream.  ... 44 centers with an emphasis on U.S. patients, ... months and older with a clinical diagnosis of ...
(Date:7/30/2015)... , July 30, 2015 ... is expected to reach USD 23.01 million in ... Research, Inc. Growing base of geriatric population, increasing prevalence ... and rising level of awareness among target customer base ... drivers over the forecast period. According to estimates published ...
(Date:7/30/2015)... , July 30, 2015  NanoSmart Pharmaceuticals, Inc., ... platforms, has received Orphan Drug Designation from the ... drug product that uses NanoSmart,s proprietary drug delivery ... dactinomycin for the treatment of Ewing,s sarcoma, a ... granted NanoSmart,s Orphan Drug Designation on the basis ...
Breaking Medicine Technology:Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 2Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 3ENT Devices Market Size to Reach $23.01 Billion by 2022: Grand View Research, Inc. 2ENT Devices Market Size to Reach $23.01 Billion by 2022: Grand View Research, Inc. 3ENT Devices Market Size to Reach $23.01 Billion by 2022: Grand View Research, Inc. 4ENT Devices Market Size to Reach $23.01 Billion by 2022: Grand View Research, Inc. 5NanoSmart Receives Second FDA Orphan Drug Designation for Treatment of Pediatric Cancer 2
... 4, 2010 Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN ... in Phoenix, Arizona on Thursday, November 11, 2010 at 5:30 ... Bradbury, president and chief executive officer of Amylin Pharmaceuticals, will ... webcast live through the "Investors" section of Amylin,s corporate website ...
... N.C., Nov. 4, 2010 Gentris Corporation ( ... pharmacogenomics, announced today that Howard McLeod, Pharm.D., from ... (UNC) has become the Company,s first Chief Scientific ... pharmacogenomics and personalized medicine, is the Fred N. ...
Cached Medicine Technology:Gentris Corporation Names New Chief Scientific Advisor 2Gentris Corporation Names New Chief Scientific Advisor 3
... enhances productivity in the laboratory with its ... methods clotting, chromogenic and immunological ... test results every time. With user ... random access, the CA-1500 will provide you ...
... Premier is our top-of-the-line device. ... attributes of the Qwik-Let® Elite, ... Lan-X feature. The Lan-X technology ... protection in the removal and ...
... the pain and hassle of testing. Unlike ... device is the only one with a ... testing, with less hassle and improved safety. ... and no side-to-side motion for less skin ...
... The new Finnpipette Focus from Thermo Labsystems ... uncompromising performance. Advanced features such as ... fine volume adjustment on microvolumes help to ... single channel pipettes. The new interchangeable handle ...
Medicine Products: