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Study Finds Ovarian Screening Tests Don't Improve Survival
Date:5/19/2011

esent their findings in June at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago.

Moreover, almost 3,300 women received false positive results from the screens. Almost 1,100 of these women went on to undergo surgical biopsies and 163 had some kind of serious complication, the study found.

Other screening techniques for ovarian cancer are being studied, including a trial led by Lu that looks at whether changes in CA-125 levels over time could pick up malignancies.

However, for the time being, successful screening for ovarian cancer remains elusive.

"This doesn't change anything in terms of standard of care," Lu said. "There is still no successful current effective method to screen for ovarian cancer."

"There's really nothing that's good at this point [for women at average risk]," Wakabayashi said. But, she pointed out that women at high risk for ovarian cancer, such as those carrying the malignancy-linked BRCA gene mutation, should still have their CA-125 checked and undergo ultrasounds.

More information

The U.S. National Cancer Institute has more on ovarian cancer.

SOURCES: Karen Lu, M.D., professor, gynecologic oncology, M.D. Anderson Cancer Center, University of Texas, Houston; Mark Wakabayashi, M.D., chief, gynecologic oncology, City of Hope Cancer Center, Duarte, Calif.


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